HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Manzanillo

$235+ Cheap flights from Key Largo, FL to Manzanillo (ZLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — ZLO
Mar 2 — Mar 91
Mon 3/2
Mon 3/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Key Largo to Manzanillo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Key Largo to Manzanillo

Cheapest flights from Key Largo to Manzanillo
Explore the most affordable flight options available from Key Largo to Manzanillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 31, 2026.

This Aeromexico deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:30 am
MIA
-
ZLO
1 stop13h 25m
Aeromexico
Wed 4/226:50 pm
ZLO
-
MIA
1 stop15h 20m
Aeromexico
Deal found 1/30$494
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
MIA
-
ZLO
2 stops13h 23m
Delta
Mon 3/1611:42 am
ZLO
-
MIA
1 stop10h 38m
Delta
Deal found 1/30$535
This Aeromexico deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:18 pm
MIA
-
ZLO
1 stop17h 17m
Aeromexico
Thu 3/1210:17 am
ZLO
-
MIA
1 stop12h 03m
Aeromexico
Deal found 1/29$567
This Aeromexico deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/128:03 am
MIA
-
ZLO
1 stop9h 45m
Aeromexico
Mon 3/166:25 pm
ZLO
-
MIA
2 stops28h 27m
Aeromexico
Deal found 1/29$704
This Aeromexico deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:49 am
MIA
-
ZLO
1 stop11h 37m
Aeromexico
Sat 6/275:28 pm
ZLO
-
MIA
1 stop16h 52m
Aeromexico
Deal found 1/31$910
This Aeromexico deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:05 am
MIA
-
ZLO
2 stops12h 18m
Aeromexico
Mon 3/166:25 pm
ZLO
-
MIA
2 stops28h 27m
Aeromexico
Deal found 1/29$926

Find flight deals from Key Largo to Manzanillo

Keep the following information in mind while searching for Key Largo to Manzanillo flight deals. Data was last updated January 31, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$494
(Delta)

One-way from

$235
(Delta)

Popular in

October

Cheapest in

July

Average price

$552
Provider with most accurate pricing for Miami-Manzanillo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Miami-Manzanillo flights.
Search Deals
From Key Largo to Manzanillo
Search Deals
One-way flight from Key Largo to Manzanillo
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Manzanillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 31, 2026.
Use the filters below to find and compare flights from Key Largo to Manzanillo that are best for you.

Fly from

Key Largo

Fly to

Manzanillo

Route

Depart

Return

Price

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Thu 3/12

8:03 am-3:48 pm

1 stop9h 45m

Manzanillo

Mon 3/16

11:42 am-12:20 am

1 stop10h 38m

$494

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Tue 4/21

6:30 am-5:55 pm

1 stop13h 25m

Manzanillo

Wed 4/22

12:20 pm-12:35 am

1 stop10h 15m

$494

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Wed 3/11

8:03 am-5:23 pm

1 stop11h 20m

Manzanillo

Mon 3/16

11:42 am-12:20 am

1 stop10h 38m

$494

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Mon 3/9

8:03 am-5:38 pm

1 stop11h 35m

Manzanillo

Thu 3/12

10:17 am-12:52 am

2 stops12h 35m

$667

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Sat 2/28

7:03 am-5:50 pm

1 stop11h 47m

$235

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Sat 2/28

7:20 pm-5:39 pm

2 stops23h 19m

$240

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Best time to book a flight from Key Largo to Manzanillo

Have a flexible travel schedule? Discover the best time to fly to Manzanillo from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Manzanillo

How much does it cost to fly round-trip from Key Largo to Manzanillo?

Reviews of airlines servicing Manzanillo

Get insights into the airlines that provide service to Manzanillo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manzanillo. Reviews last updated January 31, 2026.
Peruse reviews from past customers who have flown with Delta and Aeromexico from Key Largo to Manzanillo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,130 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,130 reviews
Delta
7.9
Good
8,130 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Aeromexico
7.4
Good
1,583 reviews
Delta
7.9
Good
8,130 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Manzanillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manzanillo from Key Largo?

    For a flight from Key Largo to Manzanillo, you will be flying into Manzanillo. Manzanillo (ZLO) is just 14.3 mi from the center of the city. Manzanillo is the only Manzanillo airport and it handles 0 inbound flights from Key Largo per day. 2 airlines have flights to Manzanillo from Key Largo on a regular basis.

  • How long is the flight from Key Largo to Manzanillo?

    Delta and Aeromexico can get you from Key Largo to Manzanillo in just under 9h 45m. Your travel time can differ by up to 3h 40m. The distance between Key Largo and Manzanillo is about 1612 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Key Largo to Manzanillo that include hotel bookings?

    Yes. In addition to deals on Key Largo to Manzanillo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Manzanillo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Manzanillo.

  • Can I find deals for business class flights from Key Largo to Manzanillo?

    Yes. Cheapflights offers flight deals from Key Largo to Manzanillo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Key Largo to Manzanillo

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Manzanillo flights
Fort Lauderdale to Manzanillo flights
Miami to Colima flights
West Palm Beach to Manzanillo flights

Top 2 airlines flying from Key Largo to Manzanillo

Discover the top 2 airlines that operate flights from Key Largo to Manzanillo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 31, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$256Average$515FlexibilityNo cancel feeOn-timeN/A
AeromexicoCheapest$396Average$538FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.