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Manzanillo

$297+ Cheap flights from Key Largo, FL to Manzanillo (ZLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — ZLO
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Key Largo to Manzanillo

Keep the following information in mind while searching for Key Largo to Manzanillo flight deals. Data was last updated October 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$459
(Delta)

One-way from

$297
(Delta)

Popular in

December

Cheapest in

February

Average price

$557
Provider with most accurate pricing for Miami-Manzanillo flight deals.
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Provider most trusted by Cheapflights users for Miami-Manzanillo flights.
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From Key Largo to Manzanillo
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One-way flight from Key Largo to Manzanillo
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Highest demand for flights based on searches. 30% potential increase in price ($254 potential increase over avg. RT price).
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Cheapest flight prices on average. 20% potential price decrease ($100 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Key Largo to Manzanillo

Cheapest flights from Key Largo to Manzanillo
Explore the most affordable flight options available from Key Largo to Manzanillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/297:02 amMIA - ZLO
1 stop11h 07mDelta
Sat 12/611:16 amZLO - MIA
1 stop10h 23mDelta
Deal found 10/30$459
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:02 amMIA - ZLO
1 stop11h 22mDelta
Wed 11/2611:26 amZLO - MIA
1 stop10h 13mDelta
Deal found 10/28$539
This Aeromexico deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:33 pmMIA - ZLO
1 stop17h 18mAeromexico
Sat 1/1011:20 amZLO - MIA
1 stop11h 04mAeromexico
Deal found 10/28$657
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:30 amMIA - ZLO
1 stop7h 27mUnited Airlines
Sat 12/61:57 pmZLO - MIA
3 stops25h 53mUnited Airlines
Deal found 10/30$676
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:01 pmMIA - ZLO
1 stop19h 27mMultiple Airlines
Fri 12/1911:33 amZLO - MIA
2 stops28h 52mMultiple Airlines
Deal found 10/28$806
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1510:03 pmMIA - ZLO
2 stops40h 51mAmerican Airlines
Sat 1/102:24 pmZLO - MIA
1 stop14h 40mAmerican Airlines
Deal found 10/28$943
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:02 amMIA - ZLO
1 stop11h 22mDelta
Fri 12/1911:33 amZLO - MIA
1 stop11h 26mDelta
Deal found 10/28$1,021
This Alaska Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:00 pmMIA - ZLO
2 stops23h 41mAlaska Airlines
Fri 12/194:49 pmZLO - MIA
2 stops46h 02mAlaska Airlines
Deal found 10/28$1,166

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Manzanillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Key Largo to Manzanillo that are best for you.

Fly from

Key Largo

Fly to

Manzanillo

Route

Depart

Return

Price

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Sat 11/29

7:02 am-5:09 pm

1 stop11h 07m

Manzanillo

Sat 12/6

11:16 am-10:39 pm

1 stop10h 23m

$459

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Fri 1/16

7:55 pm-9:31 am

1 stop14h 36m

Manzanillo

Mon 1/19

6:40 pm-11:21 am

1 stop15h 41m

$464

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Fri 11/21

7:02 am-5:24 pm

1 stop11h 22m

Manzanillo

Wed 11/26

11:26 am-10:39 pm

1 stop10h 13m

$539

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Mon 12/15

5:33 pm-9:51 am

1 stop17h 18m

Manzanillo

Sat 1/10

11:20 am-11:24 pm

1 stop11h 04m

$657

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Sat 11/29

6:30 am-12:57 pm

1 stop7h 27m

Manzanillo

Sat 12/6

1:57 pm-4:50 pm

3 stops25h 53m

$676

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Fri 12/12

4:01 pm-10:28 am

1 stop19h 27m

Manzanillo

Fri 12/19

11:33 am-5:25 pm

2 stops28h 52m

$806

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Mon 12/15

10:03 pm-1:54 pm

2 stops40h 51m

Manzanillo

Sat 1/10

2:24 pm-6:04 am

1 stop14h 40m

$943

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Fri 12/12

7:02 am-5:24 pm

1 stop11h 22m

Manzanillo

Fri 12/19

11:33 am-11:59 pm

1 stop11h 26m

$1,021

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Fri 11/7

7:02 am-5:24 pm

1 stop11h 22m

$297

MiamiManzanillo

MIA - ZLO

MIAZLO

Miami

Fri 11/7

6:50 pm-1:38 pm

2 stops19h 48m

$307

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 17 results
1
2

Best time to book a flight from Key Largo to Manzanillo

Have a flexible travel schedule? Discover the best time to fly to Manzanillo from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Manzanillo
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Manzanillo

Get insights into the airlines that provide service to Manzanillo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manzanillo. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Delta and Aeromexico from Key Largo to Manzanillo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,993 reviews

Overall

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
7,993 reviews
Delta
7.9
Good
7,993 reviews

Overall

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Aeromexico
7.4
Good
1,674 reviews
Delta
7.9
Good
7,993 reviews

Overall

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Manzanillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manzanillo from Key Largo?

    For a flight from Key Largo to Manzanillo, you will be flying into Manzanillo. Manzanillo (ZLO) is just 14.3 mi from the center of the city. Manzanillo is the only Manzanillo airport and it handles 0 inbound flights from Key Largo per day. 2 airlines have flights to Manzanillo from Key Largo on a regular basis.

  • How long is the flight from Key Largo to Manzanillo?

    Delta and Aeromexico can get you from Key Largo to Manzanillo in just under 11h 07m. Your travel time can differ by up to 3h 29m. The distance between Key Largo and Manzanillo is about 1612 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Key Largo to Manzanillo one-way?

    One-way options have recently been found by users for as low as $297 on Delta. Other airlines that offer cheap prices include American Airlines from $307 and United Airlines from $344 one-way.

  • Can I find deals for flights from Key Largo to Manzanillo that include hotel bookings?

    Yes. In addition to deals on Key Largo to Manzanillo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Manzanillo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Manzanillo.

  • Can I find deals for business class flights from Key Largo to Manzanillo?

    Yes. Cheapflights offers flight deals from Key Largo to Manzanillo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Alternative routes for Key Largo to Manzanillo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Key Largo to Manzanillo

Discover the top 2 airlines that operate flights from Key Largo to Manzanillo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$329Average$468FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$396Average$467FlexibilityNo cancel feeOn-timeN/A

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