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$591+ Cheap flights from Myrtle Beach (MYR) to Madrid, Spain (MAD)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — MAD
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$591
(Mytrip)
From Myrtle Beach Intl to Madrid Barajas
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Cheapest flights from Myrtle Beach to Madrid
Explore the most affordable flight options available from Myrtle Beach to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2812:06 pmMYR - MAD
2 stops24h 04mMultiple Airlines
Tue 11/47:40 amMAD - MYR
2 stops19h 15mMultiple Airlines
Deal found 9/13$591
This Virgin Atlantic deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/282:35 pmMYR - MAD
1 stop12h 30mVirgin Atlantic
Tue 11/411:15 amMAD - MYR
1 stop12h 48mVirgin Atlantic
Deal found 9/13$592
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/42:35 pmMYR - MAD
2 stops21h 05mDelta
Tue 12/21:05 pmMAD - MYR
2 stops26h 43mDelta
Deal found 9/14$595
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:14 amMYR - MAD
1 stop16h 16mAmerican Airlines
Thu 11/2712:30 pmMAD - MYR
2 stops28h 03mAmerican Airlines
Deal found 9/14$602
This Orbitz deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/47:41 pmMYR - MAD
1 stop28h 04mBritish Airways
Tue 12/27:40 amMAD - MYR
2 stops20h 56mBritish Airways
Deal found 9/14$646
This Orbitz deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/277:36 pmMYR - MAD
1 stop27h 54mMultiple Airlines
Sat 10/47:10 pmMAD - MYR
2 stops28h 10mMultiple Airlines
Deal found 9/14$657
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1411:29 amMYR - MAD
2 stops21h 51mDelta
Tue 11/1812:35 pmMAD - MYR
2 stops27h 59mDelta
Deal found 9/14$676
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:23 amMYR - MAD
1 stop17h 22mAmerican Airlines
Tue 11/187:20 amMAD - MYR
2 stops16h 52mAmerican Airlines
Deal found 9/13$746
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2711:32 amMYR - MAD
2 stops16h 03mDelta
Sat 10/410:25 amMAD - MYR
2 stops30h 48mDelta
Deal found 9/14$765

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Madrid that are best for you.

Fly from

Myrtle Beach

Fly to

Madrid

Route

Depart

Return

Price

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Tue 11/4

2:35 pm-5:40 pm

2 stops21h 05m

Madrid Barajas

Tue 12/2

1:05 pm-9:48 am

2 stops26h 43m

$595

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Tue 10/28

10:36 am-8:05 am

1 stop16h 29m

Madrid Barajas

Tue 11/4

10:00 am-11:57 pm

2 stops19h 57m

$597

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Thu 9/25

7:14 am-5:30 am

1 stop16h 16m

Madrid Barajas

Thu 11/27

12:30 pm-10:33 am

2 stops28h 03m

$602

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Tue 11/4

7:41 pm-5:45 am

1 stop28h 04m

Madrid Barajas

Tue 12/2

7:40 am-10:36 pm

2 stops20h 56m

$646

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Fri 11/14

11:29 am-5:40 pm

2 stops24h 11m

Madrid Barajas

Tue 11/18

12:35 pm-10:34 am

2 stops27h 59m

$676

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Tue 12/23

7:46 pm-5:45 am

1 stop27h 59m

Madrid Barajas

Mon 1/12

3:50 pm-7:14 pm

2 stops33h 24m

$788

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Thu 9/25

6:55 pm-9:35 am

1 stop32h 40m

Madrid Barajas

Thu 11/27

11:15 am-11:44 pm

1 stop18h 29m

$790

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Fri 11/14

10:31 am-9:10 pm

2 stops28h 39m

Madrid Barajas

Mon 11/17

12:55 am-4:41 pm

1 stop21h 46m

$835

Myrtle BeachMadrid

MYR - MAD

MYRMAD

Myrtle Beach Intl

Thu 9/25

2:11 pm-9:35 am

1 stop13h 24m

Madrid Barajas

Wed 11/26

12:55 am-5:00 pm

1 stop22h 05m

$843

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Myrtle Beach to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Madrid

What is the cheapest month to book a flight from Myrtle Beach to Madrid?

Currently, November is the cheapest month in which you can book a flight from Myrtle Beach to Madrid (average of $543). Flying from Myrtle Beach to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated September 15, 2025.
See what other customers who have flown with American Airlines from Myrtle Beach to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Food

6.4

Overall

7.2

Boarding

7.5

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Food

6.4

Overall

7.2

Boarding

7.5

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Madrid?

    There are many flights that can get you from Myrtle Beach to Madrid in 16h 16m. Fly via Delta, Virgin Atlantic, or American Airlines to get the fastest option. The distance between Myrtle Beach and Madrid is about 4050 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Myrtle Beach to Madrid round-trip?

    Our cheapest airline available from Myrtle Beach to Madrid is American Airlines. Our recent data shows that you can find tickets from as low as $594 on this airline.

  • Can I find deals for flights from Myrtle Beach to Madrid that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Madrid.

  • Can I find deals for business class flights from Myrtle Beach to Madrid?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Myrtle Beach to Madrid (average of $543). Flying from Myrtle Beach to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Fuenlabrada
Getafe

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Myrtle Beach to Madrid

Discover the top airline that operate flights from Myrtle Beach to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$594Average$748FlexibilityNo cancel feeOn-time71%

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