Flights from Chicago (CHI) to South Carolina (South Carolina)

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We compare hundreds of flights from Chicago to South Carolina from a range of airlines and travel agents to get you the best deals. Find cheap flights along this route.
Chicago (ORD) to Florence (FLO)
 Depart 26 Aug 15
 Return 23 Sep 15

Flying with American Airlines

Price subject to availability

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  • Dep date
  2 more OneTravel.com flights available on this route
$232   Dep 24 Aug 15 - Rtn 08 Sep 15
Chicago to Greenville-Spartanburg International
ORD to GSP OneTravel.com
$285   Dep 15 Sep 15 - Rtn 17 Sep 15
Chicago to Charleston
CHI to CHS OneTravel.com
Chicago (MDW) to Greenville-Spartanburg International (GSP)
 Depart 03 Sep 15
 Return 10 Sep 15

Price subject to availability

 
 
Chicago (ORD) to Myrtle Beach (MYR)
 Depart 17 Sep 15
 Return 23 Sep 15

Flying with Spirit Airlines

Price subject to availability

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  • Price
  • Dep date
  15 more CheapOair.com flights available on this route
$207   Dep 31 Aug 15 - Rtn 05 Sep 15
Chicago to Myrtle Beach
CHI to MYR CheapOair.com
$212   Dep 18 Sep 15 - Rtn 22 Sep 15
Chicago to Myrtle Beach
CHI to MYR CheapOair.com
$233   Dep 15 Sep 15 - Rtn 24 Sep 15
Chicago to Greenville-Spartanburg International
CHI to GSP CheapOair.com
$234   Dep 14 Oct 15 - Rtn 20 Oct 15
Chicago to Greenville-Spartanburg International
ORD to GSP CheapOair.com
$234   Dep 14 Oct 15 - Rtn 21 Oct 15
Chicago to Greenville-Spartanburg International
ORD to GSP CheapOair.com
$234   Dep 17 Oct 15 - Rtn 22 Oct 15
Chicago to Greenville-Spartanburg International
ORD to GSP CheapOair.com
$242   Dep 05 Oct 15 - Rtn 12 Oct 15
Chicago to Myrtle Beach
CHI to MYR CheapOair.com
$260   Dep 13 Aug 15 - Rtn 17 Aug 15
Chicago to Myrtle Beach
CHI to MYR CheapOair.com
$277   Dep 22 Oct 15 - Rtn 28 Oct 15
Chicago to Charleston
ORD to CHS CheapOair.com
$278   Dep 20 Oct 15 - Rtn 26 Oct 15
Chicago to Charleston
ORD to CHS CheapOair.com
$278   Dep 16 Oct 15 - Rtn 19 Oct 15
Chicago to Greenville-Spartanburg International
CHI to GSP CheapOair.com
$284   Dep 22 Oct 15 - Rtn 25 Oct 15
Chicago to Greenville-Spartanburg International
CHI to GSP CheapOair.com
$288   Dep 21 Oct 15 - Rtn 28 Oct 15
Chicago to Charleston
ORD to CHS CheapOair.com
$295   Dep 28 Aug 15 - Rtn 07 Sep 15
Chicago to Myrtle Beach
CHI to MYR CheapOair.com
$298   Dep 06 Oct 15 - Rtn 13 Oct 15
Chicago to Charleston
CHI to CHS CheapOair.com
Chicago (ORD) to Charleston (CHS)
 Depart 28 Oct 15
 Return 04 Nov 15

Flying with JetBlue Airways

Price subject to availability

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  • Price
  • Dep date
  15 more momondo.com flights available on this route
$309   Dep 21 Oct 15 - Rtn 28 Oct 15
Chicago to Charleston
ORD to CHS momondo.com
$382   Dep 14 Oct 15 - Rtn 21 Oct 15
Chicago to Charleston
ORD to CHS momondo.com
$391   Dep 07 Oct 15 - Rtn 14 Oct 15
Chicago to Charleston
ORD to CHS momondo.com
$396   Dep 04 Nov 15 - Rtn 11 Nov 15
Chicago to Charleston
ORD to CHS momondo.com
$399   Dep 30 Sep 15 - Rtn 07 Oct 15
Chicago to Charleston
ORD to CHS momondo.com
$433   Dep 23 Sep 15 - Rtn 30 Sep 15
Chicago to Charleston
ORD to CHS momondo.com
$565   Dep 23 Sep 15 - Rtn 30 Sep 15
Chicago to Charleston
ORD to CHS momondo.com
$570   Dep 07 Oct 15 - Rtn 14 Oct 15
Chicago to Charleston
ORD to CHS momondo.com
$571   Dep 14 Oct 15 - Rtn 21 Oct 15
Chicago to Charleston
ORD to CHS momondo.com
$573   Dep 30 Sep 15 - Rtn 07 Oct 15
Chicago to Charleston
ORD to CHS momondo.com
$586   Dep 04 Nov 15 - Rtn 11 Nov 15
Chicago to Charleston
ORD to CHS momondo.com
$590   Dep 14 Oct 15 - Rtn 21 Oct 15
Chicago to Charleston
MDW to CHS momondo.com
$596   Dep 07 Oct 15 - Rtn 14 Oct 15
Chicago to Charleston
MDW to CHS momondo.com
$598   Dep 04 Nov 15 - Rtn 11 Nov 15
Chicago to Charleston
MDW to CHS momondo.com
$602   Dep 23 Sep 15 - Rtn 30 Sep 15
Chicago to Charleston
MDW to CHS momondo.com
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