Flights from Chicago (CHI) to South Carolina (South Carolina)

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We compare hundreds of flights from Chicago to South Carolina from a range of airlines and travel agents to get you the best deals. Find cheap flights along this route.
Chicago (ORD) to Charleston (CHS)
 Depart 24 Feb 17
 Return 02 Mar 17

Price subject to availability

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  • Price
  • Dep date
  8 more Smartfares.com flights available on this route
$375   Dep 18 Nov 16 - Rtn 20 Nov 16
Chicago to Charleston
ORD to CHS Smartfares.com
$435   Dep 11 Nov 16 - Rtn 14 Nov 16
Chicago to Charleston
ORD to CHS Smartfares.com
$514   Dep 14 Oct 16 - Rtn 17 Oct 16
Chicago to Charleston
ORD to CHS Smartfares.com
$575   Dep 11 Nov 16 - Rtn 13 Nov 16
Chicago to Charleston
ORD to CHS Smartfares.com
$654   Dep 14 Oct 16 - Rtn 16 Oct 16
Chicago to Charleston
ORD to CHS Smartfares.com
$671   Dep 24 Nov 16 - Rtn 27 Nov 16
Chicago to Charleston
ORD to CHS Smartfares.com
$816   Dep 07 Oct 16 - Rtn 09 Oct 16
Chicago to Charleston
ORD to CHS Smartfares.com
$1,003   Dep 10 Nov 16 - Rtn 13 Nov 16
Chicago to Myrtle Beach
ORD to MYR Smartfares.com
Chicago (CHI) to Myrtle Beach (MYR)
 Depart 26 Oct 16
 Return 31 Oct 16

Flying with Spirit Airlines

Price subject to availability

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  • Price
  • Dep date
  10 more CheapOair.com flights available on this route
$136   Dep 28 Oct 16 - Rtn 02 Nov 16
Chicago to Myrtle Beach
ORD to MYR CheapOair.com
$219   Dep 12 Nov 16 - Rtn 15 Nov 16
Chicago to Columbia
ORD to CAE CheapOair.com
$222   Dep 12 Oct 16 - Rtn 15 Oct 16
Chicago to Florence
ORD to FLO CheapOair.com
$251   Dep 03 Jun 17 - Rtn 10 Jun 17
Chicago to Charleston
ORD to CHS CheapOair.com
$260   Dep 15 Oct 16 - Rtn 19 Oct 16
Chicago to Charleston
CHI to CHS CheapOair.com
$264   Dep 28 Oct 16 - Rtn 29 Oct 16
Chicago to Greenville-Spartanburg International
CHI to GSP CheapOair.com
$264   Dep 02 Dec 16 - Rtn 07 Dec 16
Chicago to Greenville-Spartanburg International
ORD to GSP CheapOair.com
$267   Dep 12 Jan 17 - Rtn 15 Jan 17
Chicago to Hilton Head Island
ORD to HHH CheapOair.com
$302   Dep 05 Dec 16 - Rtn 07 Dec 16
Chicago to Hilton Head Island
CHI to HHH CheapOair.com
$346   Dep 11 Feb 17 - Rtn 18 Feb 17
Chicago to Columbia
CHI to CAE CheapOair.com
Chicago (ORD) to Florence (FLO)
 Depart 18 Oct 16
 Return 15 Nov 16

Flying with American Airlines

Price subject to availability

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  • Price
  • Dep date
  8 more OneTravel.com flights available on this route
$230   Dep 14 Oct 16 - Rtn 19 Oct 16
Chicago to Columbia
ORD to CAE OneTravel.com
$251   Dep 08 Apr 17 - Rtn 10 Apr 17
Chicago to Charleston
ORD to CHS OneTravel.com
$251   Dep 03 Jun 17 - Rtn 10 Jun 17
Chicago to Charleston
CHI to CHS OneTravel.com
$264   Dep 02 Dec 16 - Rtn 07 Dec 16
Chicago to Greenville-Spartanburg International
ORD to GSP OneTravel.com
$272   Dep 16 Nov 16 - Rtn 15 Dec 16
Chicago to Greenville-Spartanburg International
CHI to GSP OneTravel.com
$362   Dep 13 Aug 17 - Rtn 19 Aug 17
Chicago to Hilton Head Island
CHI to HHH OneTravel.com
$375   Dep 26 Oct 16 - Rtn 27 Oct 16
Chicago to Columbia
CHI to CAE OneTravel.com
$377   Dep 04 Jun 17 - Rtn 11 Jun 17
Chicago to Hilton Head Island
ORD to HHH OneTravel.com
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