Flights from Houston (Houston) to South America (South America)

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We compare hundreds of flights from Houston to South America from a range of airlines and travel agents to get you the best deals. Find cheap flights along this route.
Houston (IAH) to Sao Paulo (GRU)
 Depart 25 Apr 16
 Return 09 May 16

Price subject to availability

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Houston (HOU) to Quito (UIO)
 Depart 19 Feb 16
 Return 29 Feb 16

Flying with Aeromexico

Price subject to availability

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  • Price
  • Dep date
  7 more OneTravel.com flights available on this route
$631   Dep 03 Mar 16 - Rtn 05 Apr 16
Houston to Sao Paulo
IAH to SAO OneTravel.com
$648   Dep 01 Apr 16 - Rtn 09 Apr 16
Houston to Cali
IAH to CLO OneTravel.com
$654   Dep 16 Mar 16 - Rtn 31 Mar 16
Houston to Rio de Janeiro
IAH to GIG OneTravel.com
$709   Dep 12 Feb 16 - Rtn 29 Feb 16
Houston to Cali
HOU to CLO OneTravel.com
$775   Dep 08 Jun 16 - Rtn 23 Jun 16
Houston to Santiago
HOU to SCL OneTravel.com
$885   Dep 30 May 16 - Rtn 13 Jun 16
Houston to Buenos Aires
IAH to EZE OneTravel.com
$1,010   Dep 09 Mar 16 - Rtn 23 Mar 16
Houston to Santa Cruz
HOU to VVI OneTravel.com
Houston (IAH) to Quito (UIO)
 Depart 22 Apr 16
 Return 02 May 16

Flying with Aeromexico

Price subject to availability

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  • Price
  • Dep date
  15 more CheapOair.com flights available on this route
$535   Dep 15 Feb 16 - Rtn 08 Mar 16
Houston to Quito
HOU to UIO CheapOair.com
$617   Dep 20 Feb 16 - Rtn 15 Mar 16
Houston to Cali
IAH to CLO CheapOair.com
$631   Dep 19 May 16 - Rtn 05 Jun 16
Houston to Sao Paulo
IAH to SAO CheapOair.com
$634   Dep 15 Apr 16 - Rtn 30 Apr 16
Houston to Sao Paulo
IAH to GRU CheapOair.com
$637   Dep 31 Mar 16 - Rtn 04 Apr 16
Houston to Rio de Janeiro
HOU to RIO CheapOair.com
$651   Dep 05 May 16 - Rtn 09 May 16
Houston to Rio de Janeiro
IAH to GIG CheapOair.com
$666   Dep 29 Mar 16 - Rtn 03 Apr 16
Houston to Rio de Janeiro
IAH to RIO CheapOair.com
$690   Dep 01 Mar 16 - Rtn 22 May 16
Houston to Cali
HOU to CLO CheapOair.com
$708   Dep 24 May 16 - Rtn 31 May 16
Houston to Santiago
IAH to SCL CheapOair.com
$757   Dep 16 Feb 16 - Rtn 08 Mar 16
Houston to Rio de Janeiro
HOU to GIG CheapOair.com
$784   Dep 18 Apr 16 - Rtn 26 Apr 16
Houston to Buenos Aires
IAH to BUE CheapOair.com
$784   Dep 06 Jun 16 - Rtn 20 Jun 16
Houston to Buenos Aires
IAH to EZE CheapOair.com
$787   Dep 17 May 16 - Rtn 14 Jun 16
Houston to Guayaquil
HOU to GYE CheapOair.com
$791   Dep 11 Apr 16 - Rtn 02 May 16
Houston to Guayaquil
IAH to GYE CheapOair.com
$844   Dep 08 Mar 16 - Rtn 15 Mar 16
Houston to Santiago
HOU to SCL CheapOair.com
Houston (HOU) to Medellin (MDE)
 Depart 22 Feb 16
 Return 01 Mar 16

Flying with Delta Air Lines

Price subject to availability

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Houston (IAH) to Cali (CLO)
 Depart 13 Apr 16
 Return 20 Apr 16

Flying with Avianca

Price subject to availability

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  • Price
  • Dep date
  15 more momondo.com flights available on this route
$525   Dep 18 Apr 16 - Rtn 25 Apr 16
Houston to Cali
IAH to CLO momondo.com
$525   Dep 23 Apr 16 - Rtn 30 Apr 16
Houston to Cali
IAH to CLO momondo.com
$597   Dep 13 Apr 16 - Rtn 20 Apr 16
Houston to Guayaquil
IAH to GYE momondo.com
$597   Dep 18 Apr 16 - Rtn 25 Apr 16
Houston to Guayaquil
IAH to GYE momondo.com
$597   Dep 23 Apr 16 - Rtn 30 Apr 16
Houston to Guayaquil
IAH to GYE momondo.com
$597   Dep 28 Apr 16 - Rtn 05 May 16
Houston to Guayaquil
IAH to GYE momondo.com
$598   Dep 08 Apr 16 - Rtn 15 Apr 16
Houston to Sao Paulo
IAH to GRU momondo.com
$613   Dep 12 Apr 16 - Rtn 19 Apr 16
Houston to Sao Paulo
IAH to GRU momondo.com
$615   Dep 28 Apr 16 - Rtn 05 May 16
Houston to Cali
IAH to CLO momondo.com
$634   Dep 03 May 16 - Rtn 10 May 16
Houston to Sao Paulo
IAH to GRU momondo.com
$640   Dep 28 Apr 16 - Rtn 05 May 16
Houston to Cali
IAH to CLO momondo.com
$680   Dep 28 Apr 16 - Rtn 05 May 16
Houston to Cali
HOU to CLO momondo.com
$704   Dep 28 Apr 16 - Rtn 05 May 16
Houston to Guayaquil
HOU to GYE momondo.com
$711   Dep 18 Apr 16 - Rtn 25 Apr 16
Houston to Sao Paulo
IAH to GRU momondo.com
$711   Dep 03 May 16 - Rtn 10 May 16
Houston to Sao Paulo
IAH to GRU momondo.com
Houston (HOU) to Quito (UIO)
 Depart 20 Feb 16
 Return 27 Feb 16

Price subject to availability

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