$138+ Cheap flights from Buffalo (BUF) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — BOG
juuli 6 — juuli 131
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to South America
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Cheapest flights from Buffalo to South AmericaExplore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juuni 6, 2026.
Explore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juuni 6, 2026.
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/166:04 pm
BUF
- MDE
2 stops28h 06m
United Airlines
L 7/49:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 6/206:09 am
BUF
- MDE
2 stops40h 01m
United Airlines
L 7/49:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/4![United Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 6/176:00 am
BUF
- MDE
2 stops16h 10m
United Airlines
R 7/39:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$440
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 6/157:52 pm
BUF
- MDE
2 stops26h 18m
United Airlines
R 7/109:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/4![United Airlines logo]()
$456
This KAYAK deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 11/27:12 pm
BUF
- MDE
2 stops18h 54m
GOL
R 11/63:10 pm
MDE
- BUF
2 stops19h 27m
GOL
Deal found 6/3![GOL logo]()
$485
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
P 11/15:26 pm
BUF
- CTG
2 stops21h 48m
American Airlines
N 11/52:34 pm
CTG
- BUF
2 stops20h 28m
American Airlines
Deal found 6/3![American Airlines logo]()
$490
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/166:00 am
BUF
- CTG
1 stop8h 15m
Delta
T 7/72:30 pm
CTG
- BUF
1 stop8h 29m
Delta
Deal found 6/4![Delta logo]()
$494
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 6/156:10 pm
BUF
- CTG
2 stops20h 05m
Delta
T 7/72:30 pm
CTG
- BUF
1 stop8h 29m
Delta
Deal found 6/4![Delta logo]()
$499
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 7/297:40 pm
BUF
- CTG
2 stops19h 37m
American Airlines
E 8/103:15 pm
CTG
- BUF
2 stops20h 23m
American Airlines
Deal found 6/2![American Airlines logo]()
$513
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
P 6/147:57 pm
BUF
- CTG
2 stops42h 18m
Delta
N 7/92:30 pm
CTG
- BUF
2 stops16h 44m
Delta
Deal found 6/4![Delta logo]()
$514
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/166:04 pm
BUF
- MDE
2 stops28h 06m
United Airlines
R 7/109:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$518
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 6/206:00 am
BUF
- CTG
1 stop8h 15m
Delta
T 7/72:30 pm
CTG
- BUF
1 stop8h 29m
Delta
Deal found 6/4![Delta logo]()
$525
Best flights from Buffalo to South AmericaDiscover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated juuni 6, 2026.
Discover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated juuni 6, 2026.
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 6/176:00 am
BUF
- MDE
2 stops16h 10m
United Airlines
L 7/49:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 11/27:12 pm
BUF
- CTG
2 stops20h 02m
American Airlines
R 11/64:15 pm
CTG
- BUF
2 stops17h 22m
American Airlines
Deal found 6/3![American Airlines logo]()
$490
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 6/206:00 am
BUF
- CTG
1 stop8h 15m
Delta
T 7/72:30 pm
CTG
- BUF
2 stops16h 44m
Delta
Deal found 6/4![Delta logo]()
$530
This Expedia deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 9/218:00 pm
BUF
- MDE
1 stop16h 20m
Multiple Airlines
K 9/3010:40 pm
MDE
- BUF
1 stop15h 55m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$629
This Expedia deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 7/298:37 pm
BUF
- CTG
1 stop15h 58m
JetBlue
E 8/102:52 pm
CTG
- BUF
1 stop15h 58m
JetBlue
Deal found 6/2![JetBlue logo]()
$659
This KAYAK deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/165:00 am
BUF
- CTG
2 stops10h 13m
GOL
L 7/41:35 pm
CTG
- BUF
2 stops19h 41m
GOL
Deal found 6/6![GOL logo]()
$659
This Orbitz deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
N 12/37:40 pm
BUF
- UIO
2 stops33h 18m
LATAM Airlines
N 12/101:29 pm
UIO
- BUF
2 stops23h 04m
LATAM Airlines
Deal found 6/5![LATAM Airlines logo]()
$746
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 6/176:00 am
BUF
- MDE
2 stops16h 10m
United Airlines
R 7/39:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 7/297:40 pm
BUF
- CTG
2 stops19h 37m
American Airlines
E 8/103:15 pm
CTG
- BUF
2 stops20h 23m
American Airlines
Deal found 6/2![American Airlines logo]()
$513
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 6/206:00 am
BUF
- CTG
1 stop8h 15m
Delta
L 7/42:30 pm
CTG
- BUF
1 stop8h 14m
Delta
Deal found 6/4![Delta logo]()
$545
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/166:04 pm
BUF
- MDE
2 stops28h 06m
United Airlines
N 7/29:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$518
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/166:04 pm
BUF
- MDE
2 stops28h 06m
United Airlines
T 7/79:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$518
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/166:00 am
BUF
- CTG
1 stop8h 15m
Delta
P 7/59:25 am
CTG
- BUF
2 stops37h 34m
Delta
Deal found 6/4![Delta logo]()
$578
This KAYAK deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 10/2110:40 am
BUF
- EZE
2 stops38h 50m
Copa Airlines
T 11/38:56 am
EZE
- BUF
2 stops26h 53m
Copa Airlines
Deal found 6/6![Copa Airlines logo]()
$1,274
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/163:00 pm
BUF
- MDE
2 stops31h 10m
United Airlines
K 7/89:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/4![United Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 6/177:27 pm
BUF
- CTG
1 stop18h 48m
Delta
T 7/72:30 pm
CTG
- BUF
2 stops16h 44m
Delta
Deal found 6/6![Delta logo]()
$616
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/163:00 pm
BUF
- MDE
2 stops31h 10m
United Airlines
E 7/69:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/4![United Airlines logo]()
$539
This Ovago deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 9/263:30 pm
BUF
- LIM
1 stop16h 25m
Multiple Airlines
K 10/712:25 pm
LIM
- BUF
1 stop18h 59m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$806
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
R 6/268:07 pm
BUF
- CTG
1 stop18h 16m
JetBlue
P 7/52:55 pm
CTG
- BUF
1 stop16h 00m
JetBlue
Deal found 6/3![JetBlue logo]()
$810
This FlightHub deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 9/307:40 am
BUF
- SDU
2 stops24h 30m
Azul
T 10/136:50 pm
SDU
- BUF
2 stops30h 08m
Azul
Deal found 6/3![Azul logo]()
$1,645
This LATAM Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 9/286:05 am
BUF
- LIM
2 stops15h 15m
LATAM Airlines
R 10/912:25 pm
LIM
- BUF
1 stop21h 09m
LATAM Airlines
Deal found 6/2![LATAM Airlines logo]()
$825
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 6/176:29 am
BUF
- CTG
2 stops31h 46m
Delta
L 7/42:30 pm
CTG
- BUF
1 stop8h 14m
Delta
Deal found 6/6![Delta logo]()
$622
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 6/206:09 am
BUF
- MDE
2 stops40h 01m
United Airlines
E 7/69:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/4![United Airlines logo]()
$539
This BusinessClass deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 9/299:15 pm
BUF
- LIM
2 stops24h 45m
Multiple Airlines
R 10/912:25 pm
LIM
- BUF
2 stops21h 49m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$813
This LATAM Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 11/147:15 pm
BUF
- LIM
1 stop11h 40m
LATAM Airlines
T 11/1712:05 am
LIM
- BUF
2 stops23h 50m
LATAM Airlines
Deal found 6/4![LATAM Airlines logo]()
$843
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 9/296:10 am
BUF
- LIM
2 stops15h 20m
American Airlines
R 10/911:59 pm
LIM
- BUF
2 stops16h 04m
American Airlines
Deal found 6/4![American Airlines logo]()
$848
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/163:00 pm
BUF
- MDE
2 stops31h 10m
United Airlines
N 7/99:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/4![United Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 9/285:30 am
BUF
- LIM
2 stops16h 00m
American Airlines
R 10/911:59 pm
LIM
- BUF
2 stops14h 53m
American Airlines
Deal found 6/2![American Airlines logo]()
$848
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 8/196:00 am
BUF
- UIO
1 stop13h 59m
Delta
E 8/246:50 pm
UIO
- BUF
2 stops19h 16m
Delta
Deal found 6/4![Delta logo]()
$708
This Trip.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 7/297:57 pm
BUF
- CTG
2 stops26h 18m
Multiple Airlines
E 8/105:35 am
CTG
- BUF
3 stops37h 39m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$896
Last-minute flights from Buffalo to South AmericaDiscover last-minute flight deals from Buffalo to South America. Data last updated juuni 6, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to South America. Data last updated juuni 6, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
P 6/147:57 pm
BUF
- CTG
2 stops42h 18m
Delta
N 7/92:30 pm
CTG
- BUF
2 stops16h 44m
Delta
Deal found 6/4![Delta logo]()
$514
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 6/157:52 pm
BUF
- MDE
2 stops26h 18m
United Airlines
L 7/49:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/4![United Airlines logo]()
$456
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 6/156:10 pm
BUF
- CTG
2 stops20h 05m
Delta
T 7/72:30 pm
CTG
- BUF
1 stop8h 29m
Delta
Deal found 6/4![Delta logo]()
$499
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/166:04 pm
BUF
- MDE
2 stops28h 06m
United Airlines
L 7/49:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/166:00 am
BUF
- CTG
1 stop8h 15m
Delta
T 7/72:30 pm
CTG
- BUF
1 stop8h 29m
Delta
Deal found 6/4![Delta logo]()
$494
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 6/166:04 pm
BUF
- MDE
2 stops28h 06m
United Airlines
R 7/109:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$518
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 6/176:00 am
BUF
- MDE
2 stops16h 10m
United Airlines
R 7/39:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$440
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
R 6/197:57 pm
BUF
- CTG
2 stops18h 18m
Delta
N 7/92:30 pm
CTG
- BUF
2 stops16h 44m
Delta
Deal found 6/4![Delta logo]()
$530
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 6/206:09 am
BUF
- MDE
2 stops40h 01m
United Airlines
L 7/49:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/4![United Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 6/206:00 am
BUF
- CTG
1 stop8h 15m
Delta
T 7/72:30 pm
CTG
- BUF
1 stop8h 29m
Delta
Deal found 6/4![Delta logo]()
$525
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 6/206:09 am
BUF
- MDE
2 stops40h 01m
United Airlines
T 7/79:45 am
MDE
- BUF
2 stops23h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 7/297:40 pm
BUF
- CTG
2 stops19h 37m
American Airlines
E 8/103:15 pm
CTG
- BUF
2 stops20h 23m
American Airlines
Deal found 6/2![American Airlines logo]()
$513
One-way flights from Buffalo to South AmericaSearch for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated juuni 6, 2026.
Search for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated juuni 6, 2026.
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 8/2210:30 am
BUF
- MDE
2 stops11h 40m
United Airlines
Deal found 6/6![United Airlines logo]()
$138
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
R 8/145:58 pm
BUF
- MDE
2 stops28h 12m
United Airlines
Deal found 6/3![United Airlines logo]()
$139
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 8/155:58 pm
BUF
- MDE
2 stops28h 12m
United Airlines
Deal found 6/3![United Airlines logo]()
$152
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
P 8/164:50 pm
BUF
- MDE
2 stops20h 58m
American Airlines
Deal found 6/3![American Airlines logo]()
$208
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
T 8/186:09 pm
BUF
- MDE
2 stops19h 39m
American Airlines
Deal found 6/3![American Airlines logo]()
$214
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 9/147:00 am
BUF
- MDE
2 stops14h 15m
American Airlines
Deal found 6/2![American Airlines logo]()
$217
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 10/213:31 pm
BUF
- CTG
2 stops21h 34m
American Airlines
Deal found 6/1![American Airlines logo]()
$222
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
K 10/217:40 pm
BUF
- CTG
1 stop18h 35m
Delta
Deal found 6/1![Delta logo]()
$227
This SmartFares deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
E 9/148:00 am
BUF
- MDE
1 stop29h 20m
JetBlue
Deal found 6/2![JetBlue logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
R 7/172:48 pm
BUF
- MDE
2 stops42h 27m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$273
This Avianca deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
P 8/168:02 pm
BUF
- MDE
1 stop10h 23m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
L 8/2210:05 pm
BUF
- MDE
3 stops30h 46m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$297
Find flight deals from Buffalo to South America
Keep the following information in mind while searching for Buffalo to South America flight deals. Data was last updated juuni 6, 2026.
Round-trip from | $345 (United Airlines) |
|---|---|
One-way from | $139 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juuni 6, 2026.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
K 6/17
6:00 am-9:10 pm
2 stops16h 10m
Medellín Jose Maria Cordova Intl
L 7/4
9:45 am-10:00 am
2 stops23h 15m
$332
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
K 6/17
6:00 am-9:10 pm
2 stops16h 10m
Medellín Jose Maria Cordova Intl
R 7/3
9:45 am-10:00 am
2 stops23h 15m
$440
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
E 11/2
7:12 pm-3:14 pm
2 stops20h 02m
Cartagena Rafael Nunez
R 11/6
4:15 pm-9:37 am
2 stops17h 22m
$490
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
K 7/29
7:40 pm-2:17 pm
2 stops19h 37m
Cartagena Rafael Nunez
E 8/10
3:15 pm-12:38 pm
2 stops20h 23m
$513
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
T 6/16
6:04 pm-9:10 pm
2 stops28h 06m
Medellín Jose Maria Cordova Intl
N 7/2
9:45 am-10:00 am
2 stops23h 15m
$518
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
T 6/16
6:04 pm-9:10 pm
2 stops28h 06m
Medellín Jose Maria Cordova Intl
T 7/7
9:45 am-10:00 am
2 stops23h 15m
$518
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
L 6/20
6:00 am-1:15 pm
1 stop8h 15m
Cartagena Rafael Nunez
T 7/7
2:30 pm-8:14 am
2 stops16h 44m
$530
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
T 6/16
3:00 pm-9:10 pm
2 stops31h 10m
Medellín Jose Maria Cordova Intl
K 7/8
9:45 am-10:00 am
2 stops23h 15m
$539
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
T 6/16
3:00 pm-9:10 pm
2 stops31h 10m
Medellín Jose Maria Cordova Intl
E 7/6
9:45 am-10:00 am
2 stops23h 15m
$539
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
L 6/20
6:09 am-9:10 pm
2 stops40h 01m
Medellín Jose Maria Cordova Intl
E 7/6
9:45 am-10:00 am
2 stops23h 15m
$539
Showing 1-10 of 59 resultsSorted by cheapest first
Best time to book a flight from Buffalo to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Buffalo with our price prediction graph.
BUF-MDE
BUF-CTG
BUF-UIO
BUF-EZE
BUF-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to South America
BUF-0SA
BUF-MDE
BUF-CTG
BUF-UIO
BUF-EZE
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated juuni 6, 2026.
Get a feel of what it's like to fly with Delta and LATAM Airlines from Buffalo to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to South America by cabin class
Find flights from Buffalo to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and South America flights
Browse other Buffalo and South America flight options. Last updated on juuni 6, 2026.
Popular flight searches
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Fly to South America countries
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Buffalo to South America flights
Consider these flights traveling from Buffalo to South America.
Top 2 airlines flying from Buffalo to South America
Discover the top 2 airlines that operate flights from Buffalo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juuni 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$320 | Average$694 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$587 | Average$806 | FlexibilityNo cancel fee | On-time81% |