$165+ Cheap flights from Odessa, TX to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — SAN
Jul 10 — Jul 171
Round-trip
1 adult, Economy
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Cheapest flights from Odessa to San DiegoExplore the most affordable flight options available from Odessa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
Explore the most affordable flight options available from Odessa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:00 am
MAF
- SAN
1 stop7h 25m
Southwest
Tue 9/228:35 am
SAN
- MAF
1 stop5h 40m
Southwest
Deal found 6/9![Southwest logo]()
$318
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:00 am
MAF
- SAN
1 stop5h 12m
American Airlines
Fri 8/217:15 am
SAN
- MAF
1 stop7h 46m
American Airlines
Deal found 6/9![American Airlines logo]()
$335
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:55 pm
MAF
- SAN
1 stop5h 30m
Southwest
Tue 7/76:40 am
SAN
- MAF
1 stop7h 35m
Southwest
Deal found 6/5![Southwest logo]()
$341
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am
MAF
- SAN
1 stop8h 17m
United Airlines
Wed 10/213:00 pm
SAN
- MAF
1 stop6h 24m
United Airlines
Deal found 6/9![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:35 pm
MAF
- SAN
1 stop6h 20m
Southwest
Mon 9/212:30 pm
SAN
- MAF
2 stops7h 05m
Southwest
Deal found 6/10![Southwest logo]()
$350
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:23 pm
MAF
- SAN
1 stop5h 36m
American Airlines
Tue 7/74:23 pm
SAN
- MAF
1 stop4h 25m
American Airlines
Deal found 6/8![American Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:55 pm
MAF
- SAN
1 stop7h 10m
Southwest
Fri 8/213:20 pm
SAN
- MAF
2 stops6h 15m
Southwest
Deal found 6/9![Southwest logo]()
$377
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:30 am
MAF
- SAN
1 stop4h 17m
American Airlines
Sat 11/144:25 pm
SAN
- MAF
1 stop4h 31m
American Airlines
Deal found 6/9![American Airlines logo]()
$379
Best flights from Odessa to San DiegoDiscover carefully curated flight deals from Odessa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
Discover carefully curated flight deals from Odessa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:55 am
MAF
- SAN
1 stop5h 30m
Southwest
Tue 9/2211:10 am
SAN
- MAF
2 stops7h 20m
Southwest
Deal found 6/9![Southwest logo]()
$323
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:23 pm
MAF
- SAN
1 stop5h 36m
American Airlines
Tue 7/74:23 pm
SAN
- MAF
1 stop4h 25m
American Airlines
Deal found 6/8![American Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:10 pm
MAF
- SAN
1 stop5h 35m
Southwest
Mon 9/214:50 pm
SAN
- MAF
1 stop4h 45m
Southwest
Deal found 6/10![Southwest logo]()
$345
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:55 pm
MAF
- SAN
1 stop5h 30m
Southwest
Tue 7/79:55 pm
SAN
- MAF
2 stops12h 40m
Southwest
Deal found 6/5![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:05 pm
MAF
- SAN
1 stop5h 50m
Southwest
Sun 11/155:20 pm
SAN
- MAF
1 stop4h 45m
Southwest
Deal found 6/9![Southwest logo]()
$399
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:05 pm
MAF
- SAN
1 stop5h 50m
Southwest
Mon 8/36:35 am
SAN
- MAF
1 stop5h 25m
Southwest
Deal found 6/8![Southwest logo]()
$407
Last-minute flights from Odessa to San DiegoDiscover last-minute flight deals from Odessa to San Diego. Data last updated June 10, 2026 and is based on user searches.
Discover last-minute flight deals from Odessa to San Diego. Data last updated June 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:00 am
MAF
- SAN
1 stop5h 51m
United Airlines
Sun 6/216:30 am
SAN
- MAF
1 stop8h 06m
United Airlines
Deal found 6/5![United Airlines logo]()
$726
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/249:32 am
MAF
- SAN
1 stop4h 18m
American Airlines
Mon 6/294:23 pm
SAN
- MAF
1 stop4h 46m
American Airlines
Deal found 6/7![American Airlines logo]()
$557
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:55 pm
MAF
- SAN
1 stop5h 30m
Southwest
Tue 7/76:40 am
SAN
- MAF
1 stop7h 35m
Southwest
Deal found 6/5![Southwest logo]()
$341
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:23 pm
MAF
- SAN
1 stop5h 36m
American Airlines
Tue 7/74:23 pm
SAN
- MAF
1 stop4h 25m
American Airlines
Deal found 6/8![American Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:05 pm
MAF
- SAN
1 stop5h 50m
Southwest
Mon 8/36:35 am
SAN
- MAF
1 stop5h 25m
Southwest
Deal found 6/8![Southwest logo]()
$407
One-way flights from Odessa to San DiegoSearch for one-way flight options from Odessa to San Diego. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
Search for one-way flight options from Odessa to San Diego. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:23 pm
MAF
- SAN
1 stop5h 36m
American Airlines
Deal found 6/7![American Airlines logo]()
$165
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:35 pm
MAF
- SAN
2 stops7h 10m
Southwest
Deal found 6/7![Southwest logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:45 am
MAF
- SAN
3 stops28h 25m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$945
Find flight deals from Odessa to San Diego
Keep the following information in mind while searching for Odessa to San Diego flight deals. Data was last updated June 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $318 (Southwest) |
One-way from | $165 (American Airlines) |
Popular in | December |
Cheapest in | March |
Average price | $419 |
Cheapflights Fare Finder
Customize your flight search to find flights from Odessa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Odessa to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Fri 9/18
9:55 am-1:25 pm
1 stop5h 30m
San Diego
Tue 9/22
11:10 am-8:30 pm
2 stops7h 20m
$323
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Fri 9/18
3:10 pm-6:45 pm
1 stop5h 35m
San Diego
Mon 9/21
4:50 pm-11:35 pm
1 stop4h 45m
$345
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Wed 7/1
4:55 pm-8:25 pm
1 stop5h 30m
San Diego
Tue 7/7
9:55 pm-12:35 pm
2 stops12h 40m
$360
Quickest round-trip
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Wed 7/1
8:23 pm-11:59 pm
1 stop5h 36m
San Diego
Tue 7/7
4:23 pm-10:48 pm
1 stop4h 25m
$363
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Fri 11/13
3:05 pm-6:55 pm
1 stop5h 50m
San Diego
Sun 11/15
5:20 pm-12:05 am
1 stop4h 45m
$399
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Fri 7/31
6:05 pm-9:55 pm
1 stop5h 50m
San Diego
Mon 8/3
6:35 am-2:00 pm
1 stop5h 25m
$407
Cheapest one-way
Quickest one-way
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Wed 7/8
8:23 pm-11:59 pm
1 stop5h 36m
$165
MidlandSan Diego
MAF - SAN
MAFSAN
Midland Intl
Wed 7/8
5:35 pm-10:45 pm
2 stops7h 10m
$209
Sorted by cheapest first
Best time to book a flight from Odessa to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Odessa with our price prediction graph.
MAF-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Odessa to San Diego
OD3-SAN
MAF-SAN
How much does it cost to fly round-trip from Odessa to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 10, 2026.
Read through reviews of airlines operating flights from Odessa to San Diego, such as Southwest and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Comfort
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
7.9
Comfort
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
7.9
Comfort
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Odessa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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Odessa and San Diego flights
Browse other Odessa and San Diego flight options. Last updated on June 10, 2026.
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Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 10, 2026.
Odessa to San Diego flights
Consider these flights traveling from Odessa to San Diego.
Top 2 airlines flying from Odessa to San Diego
Discover the top 2 airlines that operate flights from Odessa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$379 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$316 | Average$416 | FlexibilityNo cancel fee | On-time63% |