San Antonio

$124+ Cheap flights from Iowa to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Jul 9 — Jul 161
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Cheap flight deals from Iowa to San Antonio

Cheapest flights from Iowa to San Antonio
Explore the most affordable flight options available from Iowa to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
-
SAT
1 stop23h 16m
Multiple Airlines
Tue 8/117:49 pm
SAT
-
DSM
1 stop17h 45m
Multiple Airlines
Deal found 6/4$236
This Mytrip deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
OMA
-
SAT
1 stop22h 44m
Frontier
Wed 7/157:39 pm
SAT
-
OMA
1 stop23h 36m
Frontier
Deal found 6/8$239
This Booking.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:19 pm
OMA
-
SAT
1 stop22h 37m
Frontier
Tue 8/257:51 pm
SAT
-
OMA
1 stop23h 43m
Frontier
Deal found 6/6$242
This Trip.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:15 pm
OMA
-
SAT
1 stop22h 29m
Frontier
Tue 7/147:39 pm
SAT
-
OMA
1 stop23h 36m
Frontier
Deal found 6/9$253
This Booking.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:00 pm
OMA
-
SAT
1 stop22h 44m
Frontier
Tue 8/117:49 pm
SAT
-
OMA
1 stop23h 26m
Frontier
Deal found 6/8$256
This Mytrip deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:15 pm
OMA
-
SAT
1 stop22h 29m
Frontier
Fri 7/317:39 pm
SAT
-
OMA
1 stop23h 36m
Frontier
Deal found 6/7$259
This Booking.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:15 pm
OMA
-
SAT
1 stop22h 41m
Frontier
Wed 7/87:39 pm
SAT
-
OMA
1 stop23h 36m
Frontier
Deal found 6/6$261
This Booking.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:15 pm
OMA
-
SAT
1 stop22h 41m
Frontier
Sun 7/127:39 pm
SAT
-
OMA
1 stop23h 36m
Frontier
Deal found 6/4$262
This Booking.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:29 pm
OMA
-
SAT
1 stop22h 27m
Frontier
Sun 8/307:51 pm
SAT
-
OMA
1 stop23h 43m
Frontier
Deal found 6/7$263
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:30 pm
DSM
-
SAT
1 stop5h 58m
Delta
Wed 11/1810:45 am
SAT
-
DSM
1 stop6h 57m
Delta
Deal found 6/8$263
This CheapOair deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:31 pm
DSM
-
SAT
1 stop19h 41m
Frontier
Thu 10/2911:08 am
SAT
-
DSM
1 stop26h 48m
Frontier
Deal found 6/4$268
This Booking.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:15 pm
OMA
-
SAT
1 stop22h 39m
Frontier
Sat 8/157:49 pm
SAT
-
OMA
1 stop23h 26m
Frontier
Deal found 6/4$270

Find flight deals from Iowa to San Antonio

Keep the following information in mind while searching for Iowa to San Antonio flight deals. Data was last updated June 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$239
(Mytrip)

One-way from

$124
(Trip.com)

Popular in

March

Cheapest in

August

Average price

$537
Provider with most accurate pricing for Des Moines-San Antonio flight deals.
Provider most trusted by Cheapflights users for Des Moines-San Antonio flights.
From Iowa to San Antonio
One-way flight from Iowa to San Antonio
Highest demand for flights based on searches. 11% potential increase in price ($53 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Average for round-trip flights in June 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Iowa to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OmahaSan Antonio

OMA - SAT

OMASAT

Omaha Eppley Airfield

Fri 8/21

11:30 am-4:55 pm

1 stop5h 25m

San Antonio

Mon 8/24

4:12 pm-11:42 pm

2 stops7h 30m

$307

OmahaSan Antonio

OMA - SAT

OMASAT

Omaha Eppley Airfield

Wed 10/14

12:30 pm-11:10 pm

2 stops10h 40m

San Antonio

Fri 10/16

11:40 am-8:15 pm

1 stop8h 35m

$308

MolineSan Antonio

MLI - SAT

MLISAT

Moline Quad-City

Sat 10/10

6:32 am-3:53 pm

2 stops9h 21m

San Antonio

Sat 10/17

6:35 am-12:37 pm

1 stop6h 02m

$308

MolineSan Antonio

MLI - SAT

MLISAT

Moline Quad-City

Thu 9/10

5:00 pm-12:15 am

1 stop7h 15m

San Antonio

Tue 9/15

10:59 am-4:29 pm

1 stop5h 30m

$311

MolineSan Antonio

MLI - SAT

MLISAT

Moline Quad-City

Wed 9/9

8:13 am-3:43 pm

2 stops7h 30m

San Antonio

Mon 9/14

5:30 pm-10:34 pm

1 stop5h 04m

$316

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Sat 10/10

6:00 am-10:43 am

1 stop4h 43m

San Antonio

Sat 10/17

2:00 pm-9:23 pm

1 stop7h 23m

$317

Cedar RapidsSan Antonio

CID - SAT

CIDSAT

Cedar Rapids

Fri 8/7

6:30 am-12:12 pm

1 stop5h 42m

San Antonio

Tue 8/11

1:45 pm-8:53 pm

1 stop7h 08m

$319

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Thu 10/22

1:50 pm-8:00 pm

1 stop6h 10m

San Antonio

Mon 10/26

2:20 pm-11:30 pm

1 stop9h 10m

$323

Cedar RapidsSan Antonio

CID - SAT

CIDSAT

Cedar Rapids

Sat 7/4

2:42 pm-10:57 pm

1 stop8h 15m

San Antonio

Sat 7/11

1:25 pm-8:58 pm

1 stop7h 33m

$323

Cedar RapidsSan Antonio

CID - SAT

CIDSAT

Cedar Rapids

Thu 10/29

6:45 am-12:10 pm

1 stop5h 25m

San Antonio

Sat 10/31

10:45 am-10:56 pm

2 stops12h 11m

$324

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/6

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Iowa to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to San Antonio

What is the cheapest month to book a flight from Iowa to San Antonio?

Currently, February is the cheapest month in which you can book a flight from Iowa to San Antonio (average of $86). Flying from Iowa to San Antonio in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Iowa to San Antonio?

How far ahead should I book a flight from Iowa to San Antonio?

The price you pay for your flight from Iowa to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 61 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Related info for your journey

Find useful and relevant information for your journey from Iowa to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Antonio from Iowa?

    If you book a flight to San Antonio from Iowa, you will be flying to San Antonio, which is the city’s only airport. San Antonio (SAT) is located 7.6 mi from the center of San Antonio.

  • How long is the flight from Iowa to San Antonio?

    For as low as $307, United Airlines can have you in San Antonio from Iowa in 5h 25m. The distance between Iowa and San Antonio is about 826 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Iowa to San Antonio one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $92. Delta flights start at $118 while deals on American Airlines start at $132 one-way.

  • What are the most popular routes from Iowa to San Antonio?

  • Can I find deals for flights from Iowa to San Antonio that include hotel bookings?

    Yes. In addition to deals on Iowa to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to San Antonio.

  • Can I find deals for business class flights from Iowa to San Antonio?

    Yes. Cheapflights offers flight deals from Iowa to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to San Antonio?

    Currently, February is the cheapest month in which you can book a flight from Iowa to San Antonio (average of $86). Flying from Iowa to San Antonio in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

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Alternative routes for Iowa to San Antonio

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Iowa to San Antonio

Discover the top 4 airlines that operate flights from Iowa to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$213Average$362FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$234Average$374FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$375FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$359Average$421FlexibilityNo cancel feeOn-time63%

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