$290+ Cheap flights from Detroit (DTT) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PTY
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Panama with Cheapflights
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Cheapest flights from Detroit to PanamaExplore the most affordable flight options available from Detroit to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from Detroit to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 pm
DTW
- PTY
2 stops18h 00m
Multiple Airlines
Sun 10/43:50 pm
PTY
- DTW
2 stops23h 42m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$609
This FlightHub deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Sun 9/273:50 pm
PTY
- DTW
2 stops23h 42m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$617
This FlightHub deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am
DTW
- PTY
2 stops36h 55m
Multiple Airlines
Fri 12/113:50 pm
PTY
- DTW
2 stops31h 07m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$625
This Expedia deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:30 pm
DTW
- PTY
2 stops18h 00m
Multiple Airlines
Wed 10/2811:25 am
PTY
- DTW
3 stops27h 25m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$634
This Travelocity deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Thu 8/203:50 pm
PTY
- DTW
2 stops31h 08m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$644
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 pm
DTW
- PTY
2 stops18h 00m
Multiple Airlines
Tue 9/293:50 pm
PTY
- DTW
2 stops23h 42m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$665
This FlightHub deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Wed 9/303:50 pm
PTY
- DTW
2 stops23h 42m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$673
This Travelocity deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:10 am
DTW
- PTY
2 stops26h 20m
Multiple Airlines
Sat 11/143:50 pm
PTY
- DTW
2 stops24h 00m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$688
Best flights from Detroit to PanamaDiscover carefully curated flight deals from Detroit to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from Detroit to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This Justfly.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Tue 8/183:50 pm
PTY
- DTW
2 stops31h 08m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$625
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:20 am
DTW
- PTY
1 stop8h 36m
Delta
Tue 9/292:21 pm
PTY
- DTW
1 stop9h 33m
Delta
Deal found 6/6![Delta logo]()
$733
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:25 am
DTW
- PTY
2 stops14h 12m
United Airlines
Wed 9/309:45 am
PTY
- DTW
1 stop9h 54m
United Airlines
Deal found 6/9![United Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:20 am
DTW
- PTY
1 stop8h 36m
Delta
Wed 9/302:21 pm
PTY
- DTW
1 stop9h 33m
Delta
Deal found 6/8![Delta logo]()
$733
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:15 am
DTW
- PTY
1 stop11h 23m
United Airlines
Fri 11/1310:00 am
PTY
- DTW
1 stop13h 04m
United Airlines
Deal found 6/4![United Airlines logo]()
$780
Last-minute flights from Detroit to PanamaDiscover last-minute flight deals from Detroit to Panama. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Panama. Data last updated June 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/302:02 pm
DTW
- PTY
1 stop31h 32m
Multiple Airlines
Wed 7/810:25 am
PTY
- DTW
2 stops13h 15m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$785
This Priceline deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Mon 7/133:50 pm
PTY
- DTW
2 stops31h 09m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$801
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:13 pm
DTW
- PTY
1 stop28h 21m
Multiple Airlines
Wed 7/1510:26 am
PTY
- DTW
1 stop13h 14m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$796
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- PTY
1 stop12h 07m
Multiple Airlines
Tue 7/288:25 am
PTY
- DTW
2 stops26h 07m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$726
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/234:17 pm
DTW
- PTY
2 stops20h 57m
American Airlines
Fri 7/311:14 pm
PTY
- DTW
1 stop9h 42m
American Airlines
Deal found 6/9![American Airlines logo]()
$844
This Justfly.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Mon 7/273:50 pm
PTY
- DTW
2 stops31h 09m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$755
This Priceline deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Sun 7/263:50 pm
PTY
- DTW
2 stops31h 09m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$774
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:10 am
DTW
- PTY
1 stop15h 24m
Multiple Airlines
Tue 8/410:25 am
PTY
- DTW
2 stops13h 15m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$760
One-way flights from Detroit to PanamaSearch for one-way flight options from Detroit to Panama. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from Detroit to Panama. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:30 pm
DTW
- PTY
2 stops18h 00m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$290
This Expedia deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am
DTW
- PTY
2 stops37h 55m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$298
This Travelocity deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:00 am
DTW
- PTY
2 stops29h 30m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:20 am
DTW
- PTY
1 stop8h 36m
Delta
Deal found 6/8![Delta logo]()
$392
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:12 pm
DTW
- PTY
2 stops22h 50m
United Airlines
Deal found 6/8![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:20 am
DTW
- PTY
1 stop8h 36m
Delta
Deal found 6/9![Delta logo]()
$400
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:17 am
DTW
- PTY
1 stop8h 43m
American Airlines
Deal found 6/5![American Airlines logo]()
$410
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:45 am
DTW
- PTY
2 stops14h 17m
United Airlines
Deal found 6/8![United Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:12 pm
DTW
- PTY
2 stops22h 50m
United Airlines
Deal found 6/8![United Airlines logo]()
$424
This Justfly.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:00 am
DTW
- PTY
2 stops44h 55m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:20 am
DTW
- PTY
1 stop7h 35m
Delta
Deal found 6/7![Delta logo]()
$443
This oojo deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:48 pm
DTW
- PTY
3 stops20h 07m
Avianca
Deal found 6/9![Avianca logo]()
$452
Find flight deals from Detroit to Panama
Keep the following information in mind while searching for Detroit to Panama flight deals. Data was last updated June 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $609 (FlightHub) |
One-way from | $290 (FlightHub) |
Popular in | April |
Cheapest in | January |
Average price | $905 |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Detroit to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Fri 8/14
6:00 am-10:30 am
2 stops29h 30m
Panama City Tocumen Intl
Tue 8/18
3:50 pm-11:58 pm
2 stops31h 08m
$625
Quickest round-trip
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Tue 9/15
5:20 am-12:56 pm
1 stop8h 36m
Panama City Tocumen Intl
Tue 9/29
2:21 pm-12:54 am
1 stop9h 33m
$733
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Wed 9/16
5:20 am-12:56 pm
1 stop8h 36m
Panama City Tocumen Intl
Wed 9/30
2:21 pm-12:54 am
1 stop9h 33m
$733
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Wed 9/16
5:25 am-6:37 pm
2 stops14h 12m
Panama City Tocumen Intl
Wed 9/30
9:45 am-8:39 pm
1 stop9h 54m
$737
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Thu 11/5
8:15 am-7:38 pm
1 stop11h 23m
Panama City Tocumen Intl
Fri 11/13
10:00 am-11:04 pm
1 stop13h 04m
$780
Cheapest one-way
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Wed 10/28
5:45 am-7:02 pm
2 stops14h 17m
$392
Quickest one-way
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Tue 10/27
5:20 am-12:56 pm
1 stop8h 36m
$392
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Wed 10/28
5:20 am-12:56 pm
1 stop8h 36m
$400
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Tue 10/6
5:20 am-12:56 pm
1 stop8h 36m
$400
DetroitPanama City
DTW - PTY
DTWPTY
Detroit Metropolitan Wayne County
Sat 8/8
6:00 am-10:30 am
2 stops29h 30m
$461
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Detroit to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Detroit with our price prediction graph.
DTW-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Panama
DTT-PA0
DTW-PTY
What is the cheapest month to book a flight from Detroit to Panama?
Currently, March is the cheapest month in which you can book a flight from Detroit to Panama (average of $514). Flying from Detroit to Panama in November is currently the most expensive (average of $697). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Detroit to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Detroit to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to Panama by cabin class
Find flights from Detroit to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and Panama flights
Browse other Detroit and Panama flight options. Last updated on June 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Detroit to Panama
Discover the top 4 airlines that operate flights from Detroit to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$611 | Average$934 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$673 | Average$823 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$708 | Average$839 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$709 | Average$962 | FlexibilityNo cancel fee | On-timeN/A |