HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$295+ Cheap flights from Charleston (CHS) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Jul 9 — Jul 161
Thu 7/9
Thu 7/16
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Panama

Cheapest flights from Charleston to Panama
Explore the most affordable flight options available from Charleston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.

This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:30 am
CHS
-
PTY
1 stop7h 35m
Delta
Wed 11/253:30 pm
PTY
-
CHS
1 stop17h 10m
Delta
Deal found 6/8$527
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:19 am
CHS
-
PTY
2 stops10h 12m
United Airlines
Mon 9/1410:00 am
PTY
-
CHS
1 stop11h 11m
United Airlines
Deal found 6/5$531
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:55 pm
CHS
-
PTY
1 stop20h 10m
Delta
Thu 11/263:30 pm
PTY
-
CHS
1 stop17h 10m
Delta
Deal found 6/8$534
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:50 am
CHS
-
PTY
1 stop12h 47m
United Airlines
Wed 7/2910:55 pm
PTY
-
CHS
1 stop8h 56m
United Airlines
Deal found 6/8$539
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:34 pm
CHS
-
PTY
1 stop13h 30m
United Airlines
Tue 7/1410:55 pm
PTY
-
CHS
1 stop9h 11m
United Airlines
Deal found 6/8$551
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:10 am
CHS
-
PTY
1 stop8h 45m
Delta
Sat 9/52:30 pm
PTY
-
CHS
1 stop8h 29m
Delta
Deal found 6/6$559
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:30 am
CHS
-
PTY
2 stops13h 07m
United Airlines
Sat 9/510:55 pm
PTY
-
CHS
2 stops14h 03m
United Airlines
Deal found 6/6$563
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:30 am
CHS
-
PTY
1 stop27h 35m
Delta
Wed 11/253:30 pm
PTY
-
CHS
1 stop17h 10m
Delta
Deal found 6/8$564
This Orbitz deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:05 am
CHS
-
PTY
2 stops24h 25m
Multiple Airlines
Sun 10/113:50 pm
PTY
-
CHS
2 stops26h 40m
Multiple Airlines
Deal found 6/4$578
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:00 am
CHS
-
PTY
1 stop8h 14m
United Airlines
Sun 9/610:55 pm
PTY
-
CHS
1 stop14h 18m
United Airlines
Deal found 6/4$585

Find flight deals from Charleston to Panama

Keep the following information in mind while searching for Charleston to Panama flight deals. Data was last updated June 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$527
(Delta)

One-way from

$295
(United Airlines)

Popular in

April

Cheapest in

September

Average price

$543
Provider with most accurate pricing for Charleston-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Panama City Tocumen Intl flights.
Search Deals
From Charleston to Panama
Search Deals
One-way flight from Charleston to Panama
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Charleston to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 12/2

10:59 am-8:02 pm

1 stop9h 03m

Panama City Tocumen Intl

Mon 12/7

8:55 am-9:54 pm

1 stop12h 59m

$527

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 9/29

11:05 am-7:31 pm

1 stop9h 26m

Panama City Tocumen Intl

Mon 10/12

3:30 pm-10:40 am

2 stops18h 10m

$531

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 9/10

10:19 am-7:31 pm

2 stops10h 12m

Panama City Tocumen Intl

Mon 9/14

10:00 am-10:11 pm

1 stop11h 11m

$531

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 7/23

10:00 am-4:04 am

2 stops19h 04m

Panama City Tocumen Intl

Wed 7/29

10:55 pm-8:51 am

1 stop8h 56m

$543

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 7/9

3:34 pm-4:04 am

1 stop13h 30m

Panama City Tocumen Intl

Thu 7/16

10:55 pm-8:51 am

1 stop8h 56m

$551

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 7/13

6:50 am-4:12 pm

1 stop10h 22m

Panama City Tocumen Intl

Mon 7/20

10:00 am-10:15 pm

1 stop11h 15m

$551

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 7/8

2:47 pm-4:04 am

2 stops14h 17m

Panama City Tocumen Intl

Tue 7/14

9:45 am-11:52 pm

1 stop13h 07m

$555
Quickest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 8/27

5:10 am-12:55 pm

1 stop8h 45m

Panama City Tocumen Intl

Sat 9/5

2:30 pm-11:59 pm

1 stop8h 29m

$559
Cheapest one-way

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 6/22

7:47 pm-2:14 pm

2 stops19h 27m

$295
Quickest one-way

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 6/23

10:00 am-7:31 pm

2 stops10h 31m

$295

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/6

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Charleston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama

What is the cheapest month to book a flight from Charleston to Panama?

Currently, July is the cheapest month in which you can book a flight from Charleston to Panama (average of $172). Flying from Charleston to Panama in April is currently the most expensive (average of $580). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated June 9, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charleston to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,394 reviews

Comfort

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,394 reviews
Delta
7.9
Good
8,394 reviews

Comfort

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
9,796 reviews
Delta
7.9
Good
8,394 reviews

Comfort

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,640 reviews
Delta
7.9
Good
8,394 reviews

Comfort

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Panama?

    For a flight from Charleston to Panama, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to Panama?

    United Airlines can get you from Charleston to Panama in just under 9h 03m. Your travel time can differ by up to . Airlines will cover a distance of 1645 mi.

  • Can I find deals for flights from Charleston to Panama that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama.

  • Can I find deals for business class flights from Charleston to Panama?

    Yes. Cheapflights offers flight deals from Charleston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama?

    Currently, July is the cheapest month in which you can book a flight from Charleston to Panama (average of $172). Flying from Charleston to Panama in April is currently the most expensive (average of $580). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Charleston to Panama

Discover the top 3 airlines that operate flights from Charleston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$309Average$474FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$389Average$551FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$389Average$536FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.