HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Medellín

$262+ Cheap flights from Greenville (GSP) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — MDE
Jul 10 — Jul 171
Fri 7/10
Fri 7/17
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to Medellín with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greenville to Medellín

Cheapest flights from Greenville to Medellín
Explore the most affordable flight options available from Greenville to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1012:06 pm
GSP
-
MDE
1 stop10h 19m
Multiple Airlines
Sun 8/169:50 pm
MDE
-
GSP
2 stops17h 17m
Multiple Airlines
Deal found 6/8$485
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:05 pm
GSP
-
MDE
2 stops18h 43m
American Airlines
Sat 8/226:00 am
MDE
-
GSP
1 stop15h 58m
American Airlines
Deal found 6/6$575
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:42 pm
GSP
-
MDE
2 stops16h 53m
American Airlines
Sun 11/11:30 am
MDE
-
GSP
2 stops16h 39m
American Airlines
Deal found 6/9$595
This LATAM Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:45 am
GSP
-
MDE
2 stops18h 00m
LATAM Airlines
Wed 8/1211:10 pm
MDE
-
GSP
2 stops18h 54m
LATAM Airlines
Deal found 6/6$606
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:35 am
GSP
-
MDE
2 stops14h 41m
American Airlines
Tue 8/46:00 am
MDE
-
GSP
1 stop12h 30m
American Airlines
Deal found 6/8$616
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:28 pm
GSP
-
MDE
2 stops11h 11m
American Airlines
Fri 3/121:20 am
MDE
-
GSP
1 stop17h 22m
American Airlines
Deal found 6/8$625
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:50 am
GSP
-
MDE
2 stops40h 20m
United Airlines
Mon 9/219:45 am
MDE
-
GSP
2 stops27h 35m
United Airlines
Deal found 6/7$634
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:35 am
GSP
-
MDE
2 stops14h 41m
American Airlines
Tue 8/46:00 am
MDE
-
GSP
1 stop12h 30m
American Airlines
Deal found 6/8$636
This Travelocity deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:55 am
GSP
-
MDE
2 stops16h 40m
LATAM Airlines
Tue 8/185:05 am
MDE
-
GSP
2 stops12h 40m
LATAM Airlines
Deal found 6/9$637

Find flight deals from Greenville to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 10, 2026.

Round-trip from

$485
(Kiwi.com)

One-way from

$262
(Kiwi.com)

Popular in

September

Cheapest in

August

Average price

$893
From Greenville to Medellín
Search Deals
One-way flight from Greenville to Medellín
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Greenville to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 8/12

6:55 am-9:05 pm

2 stops15h 10m

Medellín Jose Maria Cordova Intl

Tue 8/18

5:05 am-6:45 pm

2 stops12h 40m

$606

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 8/12

6:40 pm-8:15 pm

1 stop26h 35m

Medellín Jose Maria Cordova Intl

Tue 8/18

1:50 pm-6:10 pm

1 stop27h 20m

$647

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 8/10

6:55 am-4:40 pm

2 stops10h 45m

Medellín Jose Maria Cordova Intl

Sun 8/16

7:45 am-9:18 am

2 stops24h 33m

$677

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 8/10

5:43 pm-9:10 pm

2 stops28h 27m

Medellín Jose Maria Cordova Intl

Sun 8/16

9:45 am-9:36 am

2 stops22h 51m

$678

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 7/12

8:00 pm-12:49 pm

1 stop17h 49m

Medellín Jose Maria Cordova Intl

Sat 7/18

12:30 am-2:04 pm

2 stops12h 34m

$687

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 7/13

8:00 pm-12:49 pm

1 stop17h 49m

Medellín Jose Maria Cordova Intl

Thu 7/16

6:00 am-7:49 pm

2 stops12h 49m

$692

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 7/30

8:00 pm-12:49 pm

1 stop17h 49m

Medellín Jose Maria Cordova Intl

Mon 8/17

6:00 am-6:10 pm

1 stop11h 10m

$704

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 7/30

6:10 am-9:10 pm

2 stops40h 00m

Medellín Jose Maria Cordova Intl

Mon 8/17

9:45 am-5:20 pm

1 stop30h 35m

$724
Cheapest one-way

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 6/15

9:43 pm-8:15 am

3 stops35h 32m

$262

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 7/26

8:37 am-11:35 pm

3 stops15h 58m

$336

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Greenville to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Medellín

What is the cheapest month to book a flight from Greenville to Medellín?

Currently, April is the cheapest month in which you can book a flight from Greenville to Medellín (average of $81). Flying from Greenville to Medellín in January is currently the most expensive (average of $660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Medellín?

How far ahead should I book a flight from Greenville to Medellín?

The best time to book flights from Greenville to Medellín is 42 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated June 10, 2026.
Get a feel of what it's like to fly with American Airlines from Greenville to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,635 reviews

Comfort

7.2

Food

6.4

Boarding

7.5

Entertainment

6.9

Crew

7.9

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,635 reviews
American Airlines
7.1
Good
11,635 reviews

Comfort

7.2

Food

6.4

Boarding

7.5

Entertainment

6.9

Crew

7.9

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Greenville to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Medellín?

    If you book a flight to Medellín from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville. There are 0 flights from Greenville to Medellín per day from 1 airline.

  • How long is the flight from Greenville to Medellín?

    LATAM Airlines and American Airlines can get you from Greenville to Medellín in just under 15h 10m. Your travel time can differ by up to 11h 25m. Airlines will cover a distance of 2030 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Greenville to Medellín round-trip?

    American Airlines, at $515, was found to be the cheapest airline from Greenville to Medellín.. Users have found that American Airlines is 33% cheaper than the other options available to this destination.

  • Can I find deals for flights from Greenville to Medellín that include hotel bookings?

    Yes. In addition to deals on Greenville to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Medellín.

  • Can I find deals for business class flights from Greenville to Medellín?

    Yes. Cheapflights offers flight deals from Greenville to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Medellín?

    Currently, April is the cheapest month in which you can book a flight from Greenville to Medellín (average of $81). Flying from Greenville to Medellín in January is currently the most expensive (average of $660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Greenville to Medellín

Discover the top airline that operate flights from Greenville to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$515Average$773FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.