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Lucerne

$396+ Cheap flights from Des Moines (DSM) to Lucerne, Switzerland

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ZRH
Jul 9 — Jul 161
Thu 7/9
Thu 7/16
1 adult, Economy
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Cheap flight deals from Des Moines to Lucerne

Cheapest flights from Des Moines to Lucerne
Explore the most affordable flight options available from Des Moines to Lucerne. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.

This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:30 am
DSM
-
ZRH
2 stops17h 25m
United Airlines
Fri 11/201:20 pm
ZRH
-
DSM
2 stops33h 54m
United Airlines
Deal found 6/4$826
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:00 am
DSM
-
ZRH
1 stop19h 55m
United Airlines
Thu 12/101:20 pm
ZRH
-
DSM
2 stops31h 51m
United Airlines
Deal found 6/8$879
This United deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:00 am
DSM
-
ZRH
2 stops19h 25m
Multiple Airlines
Wed 8/2612:40 pm
ZRH
-
DSM
2 stops30h 38m
Multiple Airlines
Deal found 6/4$928
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:23 am
DSM
-
ZRH
2 stops20h 27m
United Airlines
Fri 8/141:25 pm
ZRH
-
DSM
2 stops35h 03m
United Airlines
Deal found 6/7$929
This Gotogate deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
DSM
-
ZRH
2 stops17h 10m
Air Canada
Wed 8/1912:40 pm
ZRH
-
DSM
2 stops42h 04m
Air Canada
Deal found 6/4$931
This United deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:00 am
DSM
-
ZRH
2 stops17h 05m
Multiple Airlines
Fri 8/211:25 pm
ZRH
-
DSM
2 stops29h 53m
Multiple Airlines
Deal found 6/4$933

Find flight deals from Des Moines to Lucerne

Keep the following information in mind while searching for Des Moines to Lucerne flight deals. Data was last updated June 9, 2026.

Round-trip from

$826
(United Airlines)

One-way from

$396
(Kiwi.com)

Popular in

December

Cheapest in

February
From Des Moines to Lucerne
Search Deals
One-way flight from Des Moines to Lucerne
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($75 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($39 potential savings vs. average RT price).
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Lucerne that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Des Moines to Lucerne that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Tue 11/17

3:15 pm-2:45 pm

2 stops16h 30m

Zurich

Fri 11/20

1:20 pm-4:14 pm

2 stops33h 54m

$826

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Thu 12/3

11:30 am-7:55 am

1 stop13h 25m

Zurich

Thu 12/10

1:20 pm-2:11 pm

2 stops31h 51m

$879

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Wed 8/19

8:00 am-10:25 am

2 stops19h 25m

Zurich

Wed 8/26

12:40 pm-12:18 pm

2 stops30h 38m

$928
Quickest round-trip

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Wed 8/26

11:32 am-7:45 am

1 stop13h 13m

Zurich

Tue 9/8

1:25 pm-10:26 am

2 stops28h 01m

$932

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Sun 8/23

1:10 pm-7:45 am

1 stop11h 35m

Zurich

Sat 9/5

1:25 pm-12:18 pm

2 stops29h 53m

$993
Cheapest one-way

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Mon 8/17

7:35 am-9:20 pm

2 stops30h 45m

$400

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Mon 8/17

5:21 pm-4:35 pm

2 stops16h 14m

$460
Quickest one-way

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Mon 8/17

11:28 am-8:05 am

1 stop13h 37m

$463

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Wed 8/26

8:00 am-10:00 am

3 stops19h 00m

$471

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/5

Sorted by cheapest first

Best time to book a flight from Des Moines to Lucerne

Have a flexible travel schedule? Discover the best time to fly to Lucerne from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Lucerne
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Lucerne

Get insights into the airlines that provide service to Lucerne. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lucerne. Reviews last updated June 9, 2026.
See what other customers who have flown with Delta and United Airlines from Des Moines to Lucerne have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,394 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,394 reviews
Delta
7.9
Good
8,394 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
9,796 reviews
Delta
7.9
Good
8,394 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Lucerne. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Lucerne?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Lucerne from Des Moines. Booking flights from Des Moines (DSM) to Lucerne should be relatively easy as there are 0 daily outbound flights to Lucerne from 2 different airlines.

  • How long is the flight from Des Moines to Lucerne?

    Airlines like United Airlines fly from Des Moines to Lucerne in about 16h 30m. The time it takes to get you to your destination can typically vary by up to . The distance from Des Moines to Lucerne is about 4666 mi.

  • Can I find deals for flights from Des Moines to Lucerne that include hotel bookings?

    Yes. In addition to deals on Des Moines to Lucerne flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Lucerne?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Lucerne.

  • Can I find deals for business class flights from Des Moines to Lucerne?

    Yes. Cheapflights offers flight deals from Des Moines to Lucerne by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Des Moines to Lucerne

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Top 2 airlines flying from Des Moines to Lucerne

Discover the top 2 airlines that operate flights from Des Moines to Lucerne. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$533Average$899FlexibilityNo cancel feeOn-time69%
DeltaCheapest$802Average$885FlexibilityNo cancel feeOn-timeN/A

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