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Cheap flights from Myrtle Beach to Knoxville (MYR - TYS) from $155

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
MYR — TYS
May 18 — May 251
From?
To?
Sat 5/18
Sat 5/25
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 13, 2024.

Popular in

July

Cheapest in

January

Round-trip from

$302

One-way from

$163
High demand for flights, 49% potential price rise
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Best time to find cheap flights, 38% potential price drop
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From Myrtle Beach Intl to Knoxville McGhee Tyson
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One-way flight from Myrtle Beach Intl to Knoxville McGhee Tyson
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What is the cheapest day to fly round-trip from Myrtle Beach to Knoxville?

Saturday flights are generally found to be more expensive for flights from Myrtle Beach to Knoxville. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Knoxville.

What is the cheapest month to fly from Myrtle Beach to Knoxville?

January can be a great time to fly to Knoxville from Myrtle Beach with a flight ticket averaging about $459. Cheapflights users have found deals in the month of January for as cheap as $241. The most expensive prices can be found in the month of July.

When is the cheapest time to fly from Myrtle Beach to Knoxville (MYR - TYS)?

Unlike at noon, when flights are generally more expensive, you can save up to 29% on flights from Myrtle Beach to Knoxville by exploring options for tickets in the morning.

Cheap American Airlines flights from Myrtle Beach to Knoxville

Explore cheap flight options specifically provided by American Airlines for the route between Myrtle Beach and Knoxville. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,633,403 searches. Data last updated May 13, 2024.
Check out some of the cheapest American Airlines flights we've come across from Myrtle Beach to Knoxville. Deals update often to give you more flight options matching your criteria
Fri 6/76:45 amMYR - TYS
1 stop5h 29mAmerican Airlines
Fri 6/147:40 pmTYS - MYR
1 stop4h 09mAmerican Airlines
Deal found 5/12$285
Sat 6/225:01 amMYR - TYS
1 stop3h 35mAmerican Airlines
Sun 6/236:11 pmTYS - MYR
1 stop3h 49mAmerican Airlines
Deal found 5/11$410
Tue 6/49:04 amMYR - TYS
1 stop3h 04mAmerican Airlines
Wed 6/57:40 pmTYS - MYR
1 stop4h 22mAmerican Airlines
Deal found 5/10$507
Fri 6/76:45 amMYR - TYS
2 stops9h 37mAmerican Airlines
Fri 6/146:11 pmTYS - MYR
1 stop5h 38mAmerican Airlines
Deal found 5/12$727
Sat 6/2210:37 amMYR - TYS
2 stops8h 40mAmerican Airlines
Sun 6/236:45 amTYS - MYR
2 stops6h 19mAmerican Airlines
Deal found 5/11$900

Cheap Delta flights from Myrtle Beach to Knoxville

Explore cheap flight options specifically provided by Delta for the route between Myrtle Beach and Knoxville. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,633,403 searches. Data last updated May 13, 2024.
Browse through some of the cheapest Delta flights traveling from Myrtle Beach to Knoxville. Deals frequently update to provide users with more options.
Tue 6/45:26 pmMYR - TYS
1 stop4h 27mDelta
Wed 6/57:46 amTYS - MYR
2 stops15h 27mDelta
Deal found 5/10$651
Tue 6/41:07 pmMYR - TYS
2 stops9h 04mDelta
Wed 6/57:46 amTYS - MYR
2 stops8h 48mDelta
Deal found 5/10$729

Cheap Myrtle Beach to Knoxville flights in May & June 2024

Find cheap flight options from Myrtle Beach to Knoxville specifically for the months of May and June 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,633,403 searches. Prices were last updated on May 13, 2024.
Check out some of the best flight deals from Myrtle Beach to Knoxville in 2024. More deals are always being added, so be sure to check back regularly.
Fri 6/78:12 pmMYR - TYS
1 stop15h 43mMultiple Airlines
Fri 6/148:10 amTYS - MYR
1 stop11h 11mMultiple Airlines
Deal found 5/10$244
Fri 6/72:32 pmMYR - TYS
2 stops21h 23mMultiple Airlines
Fri 6/148:10 amTYS - MYR
1 stop11h 11mMultiple Airlines
Deal found 5/10$279
Fri 6/78:30 amMYR - TYS
3 stops27h 25mMultiple Airlines
Fri 6/148:10 amTYS - MYR
1 stop11h 11mMultiple Airlines
Deal found 5/10$281
Fri 6/76:45 amMYR - TYS
1 stop5h 29mAmerican Airlines
Fri 6/147:40 pmTYS - MYR
1 stop4h 09mAmerican Airlines
Deal found 5/12$285
Fri 6/78:30 amMYR - TYS
3 stops27h 25mMultiple Airlines
Fri 6/146:30 amTYS - MYR
2 stops17h 58mMultiple Airlines
Deal found 5/10$324
Sat 6/225:01 amMYR - TYS
1 stop3h 35mAmerican Airlines
Sun 6/236:11 pmTYS - MYR
1 stop3h 49mAmerican Airlines
Deal found 5/11$410
Tue 6/49:04 amMYR - TYS
1 stop3h 04mAmerican Airlines
Wed 6/57:40 pmTYS - MYR
1 stop4h 22mAmerican Airlines
Deal found 5/10$507
Tue 6/45:26 pmMYR - TYS
1 stop4h 27mDelta
Wed 6/57:46 amTYS - MYR
2 stops15h 27mDelta
Deal found 5/10$651
Fri 6/76:45 amMYR - TYS
2 stops9h 37mAmerican Airlines
Fri 6/146:11 pmTYS - MYR
1 stop5h 38mAmerican Airlines
Deal found 5/12$727

Myrtle Beach to Knoxville 2024 flight deals

Discover exclusive flight deals for travel between Myrtle Beach and Knoxville in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,633,403 searches. Data last updated May 13, 2024.
Check out some of the best flight deals from Myrtle Beach to Knoxville in 2024. More deals are always being added, so be sure to check back regularly.
Fri 6/78:12 pmMYR - TYS
1 stop15h 43mMultiple Airlines
Fri 6/148:10 amTYS - MYR
1 stop11h 11mMultiple Airlines
Deal found 5/10$244
Fri 6/72:32 pmMYR - TYS
2 stops21h 23mMultiple Airlines
Fri 6/148:10 amTYS - MYR
1 stop11h 11mMultiple Airlines
Deal found 5/10$279
Fri 6/78:30 amMYR - TYS
3 stops27h 25mMultiple Airlines
Fri 6/148:10 amTYS - MYR
1 stop11h 11mMultiple Airlines
Deal found 5/10$281
Fri 6/76:45 amMYR - TYS
1 stop5h 29mAmerican Airlines
Fri 6/147:40 pmTYS - MYR
1 stop4h 09mAmerican Airlines
Deal found 5/12$285
Fri 6/78:30 amMYR - TYS
3 stops27h 25mMultiple Airlines
Fri 6/146:30 amTYS - MYR
2 stops17h 58mMultiple Airlines
Deal found 5/10$324
Sat 6/225:01 amMYR - TYS
1 stop3h 35mAmerican Airlines
Sun 6/236:11 pmTYS - MYR
1 stop3h 49mAmerican Airlines
Deal found 5/11$410
Tue 6/49:04 amMYR - TYS
1 stop3h 04mAmerican Airlines
Wed 6/57:40 pmTYS - MYR
1 stop4h 22mAmerican Airlines
Deal found 5/10$507
Tue 6/45:26 pmMYR - TYS
1 stop4h 27mDelta
Wed 6/57:46 amTYS - MYR
2 stops15h 27mDelta
Deal found 5/10$651
Fri 6/76:45 amMYR - TYS
2 stops9h 37mAmerican Airlines
Fri 6/146:11 pmTYS - MYR
1 stop5h 38mAmerican Airlines
Deal found 5/12$727

One-way flights to Knoxville from Myrtle Beach

Search for one-way flight options from Myrtle Beach to Knoxville. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 2,633,403 searches. Data last updated May 13, 2024.
Users in need of a one-way flight from Myrtle Beach to Knoxville can choose from these deals. Users can also find round-trip Myrtle Beach to Knoxville flights by using the search form above.
Wed 5/221:00 pmMYR - TYS
1 stop4h 30mAmerican Airlines
Deal found 5/12$155
Wed 7/32:32 pmMYR - TYS
1 stop5h 00mMultiple Airlines
Deal found 5/12$157
Sun 7/72:58 pmMYR - TYS
1 stop8h 13mAllegiant Air
Deal found 5/12$163
Wed 7/33:36 pmMYR - TYS
2 stops26h 55mMultiple Airlines
Deal found 5/12$196
Wed 5/221:00 pmMYR - TYS
1 stop7h 31mAmerican Airlines
Deal found 5/11$205
Sun 7/76:56 pmMYR - TYS
2 stops20h 57mMultiple Airlines
Deal found 5/12$221
Wed 7/35:47 pmMYR - TYS
3 stops24h 44mMultiple Airlines
Deal found 5/12$224
Sun 7/710:21 amMYR - TYS
3 stops29h 32mMultiple Airlines
Deal found 5/12$307
Thu 5/239:04 amMYR - TYS
1 stop5h 09mAmerican Airlines
Deal found 5/11$373

Find flights from Myrtle Beach to Knoxville within your budget

Customize your flight search to find flights from Myrtle Beach to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,633,403 searches. Data last updated May 13, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$244 - $729

Route

Depart

Return

Price

Myrtle Beach IntlKnoxville McGhee Tyson

MYR - TYS

MYRTYS

Myrtle Beach Intl

Fri 6/7

1 stop15h 43m

Knoxville McGhee Tyson

Fri 6/14

1 stop11h 11m

$244

Myrtle Beach IntlKnoxville McGhee Tyson

MYR - TYS

MYRTYS

Myrtle Beach Intl

Fri 6/7

2 stops21h 23m

Knoxville McGhee Tyson

Fri 6/14

1 stop11h 11m

$279

Myrtle Beach IntlKnoxville McGhee Tyson

MYR - TYS

MYRTYS

Myrtle Beach Intl

Fri 6/7

3 stops27h 25m

Knoxville McGhee Tyson

Fri 6/14

1 stop11h 11m

$281

Myrtle Beach IntlKnoxville McGhee Tyson

MYR - TYS

MYRTYS

Myrtle Beach Intl

Fri 6/7

1 stop5h 29m

Knoxville McGhee Tyson

Fri 6/14

1 stop4h 09m

$285

Myrtle Beach IntlKnoxville McGhee Tyson

MYR - TYS

MYRTYS

Myrtle Beach Intl

Fri 6/7

3 stops27h 25m

Knoxville McGhee Tyson

Fri 6/14

2 stops17h 58m

$324

Myrtle Beach IntlKnoxville McGhee Tyson

MYR - TYS

MYRTYS

Myrtle Beach Intl

Sat 6/22

1 stop3h 35m

Knoxville McGhee Tyson

Sun 6/23

1 stop3h 49m

$410

Myrtle Beach IntlKnoxville McGhee Tyson

MYR - TYS

MYRTYS

Myrtle Beach Intl

Tue 6/4

1 stop3h 04m

Knoxville McGhee Tyson

Wed 6/5

1 stop4h 22m

$507

Myrtle Beach IntlKnoxville McGhee Tyson

MYR - TYS

MYRTYS

Myrtle Beach Intl

Tue 6/4

1 stop4h 27m

Knoxville McGhee Tyson

Wed 6/5

2 stops15h 27m

$651

Myrtle Beach IntlKnoxville McGhee Tyson

MYR - TYS

MYRTYS

Myrtle Beach Intl

Tue 6/4

2 stops9h 04m

Knoxville McGhee Tyson

Wed 6/5

2 stops8h 48m

$729

Flights are sorted by cheapest first

Deals found on 5/10

When is the cheapest time to fly from Myrtle Beach to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Knoxville. Price data was last updated on May 5, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their Myrtle Beach to Knoxville flight should consider departing on Saturday mornings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Average price of flights to Knoxville by month

Plan your trip from Myrtle Beach to Knoxville by taking into account the cheapest months to travel. The average price of a one-way flight from Myrtle Beach to Knoxville is currently $222 while a round-trip flight costs $412. Price data was last updated on May 5, 2024.

Currently, February is the cheapest month in which you can book a flight from Myrtle Beach to Knoxville (average of $302). Flying from Myrtle Beach to Knoxville in May is currently the most expensive (average of $379). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

January

$304

February

$302

March

$370

April

$376

May

$379

June

$377

July

$346

August

$319

September

$327

October

$332

November

$373

December

$304

Temperature and rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature and rainfall totals by month.

TYS

Temperature

39.2 - 78.8 °F

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 13, 2024.
Read reviews from past customers who have flown American Airlines and Delta from Myrtle Beach to Knoxville. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
10,745 reviews
Check prices

Food

7.4

Crew

8.6

Entertainment

8.0

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Delta
8.0
Very good
10,745 reviews
Delta
8.0
Very good
10,745 reviews
Check prices

Food

7.4

Crew

8.6

Entertainment

8.0

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Allegiant Air
7.5
Good
1,020 reviews
Delta
8.0
Very good
10,745 reviews
Check prices

Food

7.4

Crew

8.6

Entertainment

8.0

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

United Airlines
7.4
Good
10,981 reviews
Delta
8.0
Very good
10,745 reviews
Check prices

Food

7.4

Crew

8.6

Entertainment

8.0

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

American Airlines
7.3
Good
14,608 reviews
Delta
8.0
Very good
10,745 reviews
Check prices

Food

7.4

Crew

8.6

Entertainment

8.0

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find flights from Myrtle Beach to Knoxville for under $300 on Cheapflights?

    Yes, there are multiple flights from Myrtle Beach to Knoxville for under $300. The cheapest flight booked recently is on Multiple Airlines for just $244, but on average you can expect to pay $485.

  • What are the cheapest airlines flying from Myrtle Beach to Knoxville round-trip?

    According to our current data, American Airlines ($285), and Delta ($651) offers the cheapest pricing from Myrtle Beach to Knoxville. American Airlines is priced at 37% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Myrtle Beach to Knoxville one-way?

    One-way options have recently been found by users for as low as $155 on American Airlines. Other airlines that offer cheap prices include Allegiant Air from $163 and United Airlines from $379 one-way.

  • What does MYR to TYS mean?

    MYR stands for Myrtle Beach Intl Airport, while TYS stands for Knoxville McGhee Tyson Airport. These codes are often called IATA codes, a set of identifiers established by IATA (International Air Transport Association) that is widely used by airlines and the aviation industry.

  • Can I find deals for flights from Myrtle Beach to Knoxville that include extra baggage allowance?

    The amount of baggage you can bring on your Myrtle Beach to Knoxville flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Myrtle Beach to Knoxville with specific airlines?

    Yes, Cheapflights allows you to browse and filter Myrtle Beach to Knoxville flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Myrtle Beach to Knoxville that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Knoxville.

  • Can I find deals for business class flights from Myrtle Beach to Knoxville?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Myrtle Beach to Knoxville that allow pets onboard?

    Many airlines flying from Myrtle Beach to Knoxville offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Myrtle Beach to Knoxville?

    Yes, you can often find last-minute deals on Myrtle Beach to Knoxville flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Myrtle Beach to Knoxville flight deals updated?

    The Myrtle Beach to Knoxville flight deals you see on this page were last updated on 5/12.

See more FAQs

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Top 2 airlines flying from Myrtle Beach to Knoxville

Discover the top 2 airlines that operate flights from Myrtle Beach to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,633,403 searches. Data last updated May 13, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$226Average$427FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapest$228Average$376FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
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Search flights from Myrtle Beach to Knoxville by cabin class

Find flights from Myrtle Beach to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
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Not ready to book yet? You can track prices for flights from Myrtle Beach to Knoxville on Cheapflights with our Price Alert feature and get notified when better prices are available.

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