HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$105+ Cheap flights from Indiana to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel.
IND — DSM
Jul 13 — Jul 201
Mon 7/13
Mon 7/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indiana to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indiana to Des Moines

Cheapest flights from Indiana to Des Moines
Explore the most affordable flight options available from Indiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.

This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:00 pm
IND
-
DSM
1 stop6h 10m
Southwest
Wed 8/266:10 am
DSM
-
IND
1 stop5h 10m
Southwest
Deal found 6/8$251
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:57 pm
ORD
-
DSM
1 stop15h 37m
Multiple Airlines
Mon 8/1010:06 pm
DSM
-
ORD
1 stop31h 31m
Multiple Airlines
Deal found 6/12$255
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:05 am
MDW
-
DSM
Nonstop1h 20m
Southwest
Mon 8/103:50 pm
DSM
-
MDW
Nonstop1h 20m
Southwest
Deal found 6/11$255
This Booking.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/219:57 pm
ORD
-
DSM
1 stop15h 37m
Frontier
Mon 7/272:19 pm
DSM
-
ORD
1 stop6h 33m
Frontier
Deal found 6/8$261
This Frontier deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:57 pm
ORD
-
DSM
1 stop15h 37m
Frontier
Mon 8/102:19 pm
DSM
-
ORD
1 stop6h 33m
Frontier
Deal found 6/11$264
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2812:59 pm
ORD
-
DSM
Nonstop1h 28m
United Airlines
Wed 7/293:24 pm
DSM
-
ORD
Nonstop1h 39m
United Airlines
Deal found 6/10$269
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:10 am
MDW
-
DSM
Nonstop1h 20m
Southwest
Wed 7/295:20 am
DSM
-
MDW
Nonstop1h 20m
Southwest
Deal found 6/10$269
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:57 pm
ORD
-
DSM
1 stop15h 37m
Frontier
Mon 8/172:19 pm
DSM
-
ORD
1 stop6h 33m
Frontier
Deal found 6/12$271
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:54 am
ORD
-
DSM
Nonstop1h 31m
American Airlines
Mon 8/106:55 am
DSM
-
ORD
Nonstop1h 50m
American Airlines
Deal found 6/12$273
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:52 pm
ORD
-
DSM
1 stop25h 55m
Multiple Airlines
Mon 8/1010:06 pm
DSM
-
ORD
1 stop31h 31m
Multiple Airlines
Deal found 6/11$274
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:55 pm
ORD
-
DSM
Nonstop1h 28m
United Airlines
Mon 9/73:20 pm
DSM
-
ORD
Nonstop1h 43m
United Airlines
Deal found 6/10$277
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:50 pm
MDW
-
DSM
Nonstop1h 20m
Southwest
Fri 8/143:50 pm
DSM
-
MDW
Nonstop1h 20m
Southwest
Deal found 6/8$277

Find flight deals from Indiana to Des Moines

Keep the following information in mind while searching for Indiana to Des Moines flight deals. Data was last updated June 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$251
(Southwest)

One-way from

$105
(American Airlines)

Popular in

April

Cheapest in

December

Average price

$426
Provider with most accurate pricing for Indianapolis-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Des Moines flights.
Search Deals
From Indiana to Des Moines
Search Deals
One-way flight from Indiana to Des Moines
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
Use the filters below to find and compare flights from Indiana to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Tue 7/28

10:10 am-11:30 am

Nonstop1h 20m

Des Moines

Wed 7/29

3:45 pm-5:05 pm

Nonstop1h 20m

$269

KalamazooDes Moines

AZO - DSM

AZODSM

Kalamazoo Intl

Fri 9/4

4:20 pm-7:19 pm

1 stop3h 59m

Des Moines

Sun 9/6

7:56 pm-12:41 am

1 stop3h 45m

$278

KalamazooDes Moines

AZO - DSM

AZODSM

Kalamazoo Intl

Wed 7/8

3:00 pm-8:49 pm

1 stop6h 49m

Des Moines

Wed 7/15

6:00 am-11:00 am

1 stop4h 00m

$278

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Tue 7/21

10:10 am-11:30 am

Nonstop1h 20m

Des Moines

Mon 7/27

4:40 pm-6:00 pm

Nonstop1h 20m

$291

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Fri 7/3

6:03 pm-9:43 pm

1 stop28h 40m

Des Moines

Thu 7/9

5:08 pm-11:31 pm

1 stop29h 23m

$296

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 8/18

5:15 am-10:26 am

1 stop6h 11m

Des Moines

Wed 8/19

3:20 pm-8:36 pm

1 stop4h 16m

$297

IndianapolisDes Moines

IND - DSM

INDDSM

Indianapolis

Tue 10/6

1:38 pm-5:33 pm

1 stop4h 55m

Des Moines

Wed 10/7

11:27 am-4:34 pm

1 stop4h 07m

$299

IndianapolisDes Moines

IND - DSM

INDDSM

Indianapolis

Thu 7/30

4:05 pm-11:35 pm

2 stops8h 30m

Des Moines

Wed 8/5

2:40 pm-10:45 pm

1 stop7h 05m

$299

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sat 9/26

12:50 pm-2:15 pm

Nonstop1h 25m

Des Moines

Wed 9/30

6:55 pm-8:33 pm

Nonstop1h 38m

$302

IndianapolisDes Moines

IND - DSM

INDDSM

Indianapolis

Wed 10/7

1:50 pm-9:50 pm

2 stops9h 00m

Des Moines

Fri 10/9

5:35 am-12:00 pm

1 stop5h 25m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Indiana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Des Moines

What is the cheapest month to book a flight from Indiana to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Indiana to Des Moines (average of $164). Flying from Indiana to Des Moines in June is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Indiana to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from Indiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Indiana?

    For a flight from Indiana to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Indiana to Des Moines?

    Airlines like Southwest, American Airlines, and Delta fly from Indiana to Des Moines in about 1h 20m. The time it takes to get you to your destination can typically vary by up to 5h 29m. The distance from Indiana to Des Moines is about 305 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Indiana to Des Moines?

    Most travelers choose Chicago O'Hare Intl - Des Moines, Chicago Midway - Des Moines or Cincinnati Cinci./N. Kentucky - Des Moines when deciding on the best route from Indiana to Des Moines.

  • Can I find deals for flights from Indiana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Indiana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Des Moines.

  • Can I find deals for business class flights from Indiana to Des Moines?

    Yes. Cheapflights offers flight deals from Indiana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Indiana to Des Moines (average of $164). Flying from Indiana to Des Moines in June is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Clive
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indiana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Atlanta to Omaha flights
Dallas/Fort Worth to Omaha flights
Hobby to Des Moines flights
George Bush Intcntl to Des Moines flights
Reagan-National to Omaha flights
LaGuardia to Omaha flights
Denver to Omaha flights
O'Hare Intl to Omaha flights
Denver to Des Moines flights
Seattle to Omaha flights
Denver to Cedar Rapids flights
Reagan-National to Des Moines flights
Newark to Omaha flights
John F Kennedy Intl to Omaha flights
Dulles Intl to Omaha flights
Baltimore to Omaha flights
Philadelphia to Omaha flights
Charlotte to Omaha flights
Dulles Intl to Des Moines flights
Sky Harbor Intl to Des Moines flights
Los Angeles to Omaha flights
Hobby to Omaha flights
Nashville to Omaha flights
George Bush Intcntl to Omaha flights
Baltimore to Des Moines flights
San Francisco to Omaha flights
Pittsburgh to Omaha flights
Dallas/Fort Worth to Des Moines flights
Charleston to Omaha flights
LaGuardia to Des Moines flights
Sky Harbor Intl to Omaha flights
Raleigh to Omaha flights
Salt Lake City to Omaha flights
Los Angeles to Des Moines flights
Birmingham to Omaha flights
Portland to Omaha flights
Dallas/Fort Worth to Cedar Rapids flights
Orlando to Omaha flights
Baltimore to Cedar Rapids flights
Atlanta to Des Moines flights
O'Hare Intl to Des Moines flights
San Francisco to Des Moines flights
Newark to Cedar Rapids flights
Boston to Omaha flights
John F Kennedy Intl to Des Moines flights
New Orleans to Omaha flights
Newark to Moline flights
Columbus to Omaha flights

Top 3 airlines flying from Indiana to Des Moines

Discover the top 3 airlines that operate flights from Indiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$200Average$353FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$350FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$228Average$348FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.