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Des Moines

$167+ Cheap flights from Fort Myers to Des Moines (RSW - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — DSM
Jul 12 — Jul 191
Sun 7/12
Sun 7/19
1 adult, Economy
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Cheap flight deals from Fort Myers to Des Moines

Cheapest flights from Fort Myers to Des Moines
Explore the most affordable flight options available from Fort Myers to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:38 pm
RSW
-
DSM
Nonstop3h 15m
Multiple Airlines
Thu 10/158:43 am
DSM
-
RSW
1 stop26h 07m
Multiple Airlines
Deal found 6/12$300
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:39 pm
RSW
-
DSM
1 stop7h 12m
United Airlines
Tue 7/78:00 am
DSM
-
RSW
1 stop5h 44m
United Airlines
Deal found 6/8$359
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:16 am
RSW
-
DSM
2 stops8h 05m
American Airlines
Tue 7/71:41 pm
DSM
-
RSW
1 stop5h 52m
American Airlines
Deal found 6/8$372
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:22 am
RSW
-
DSM
1 stop7h 34m
American Airlines
Thu 7/96:30 am
DSM
-
RSW
1 stop5h 54m
American Airlines
Deal found 6/12$390
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/132:32 pm
RSW
-
DSM
1 stop7h 36m
Delta
Tue 7/142:45 pm
DSM
-
RSW
1 stop7h 09m
Delta
Deal found 6/10$393
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:01 am
RSW
-
DSM
1 stop6h 33m
American Airlines
Wed 7/155:12 am
DSM
-
RSW
2 stops8h 57m
American Airlines
Deal found 6/10$406

Find flight deals from Fort Myers to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$300
(Kiwi.com)

One-way from

$167
(American Airlines)

Popular in

March

Cheapest in

December

Average price

$417
Provider with most accurate pricing for Fort Myers SW Florida Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Des Moines flights.
Search Deals
From Fort Myers SW Florida Intl to Des Moines
Search Deals
One-way flight from Fort Myers SW Florida Intl to Des Moines
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($112 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Fort Myers to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Mon 10/12

7:38 pm-9:53 pm

Nonstop3h 15m

Des Moines

Thu 10/15

8:43 am-11:50 am

1 stop26h 07m

$300

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Tue 7/7

7:00 am-2:05 pm

1 stop8h 05m

Des Moines

Thu 7/9

6:37 pm-12:23 am

1 stop4h 46m

$393

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Thu 7/9

7:01 am-12:34 pm

1 stop6h 33m

Des Moines

Wed 7/15

5:12 am-3:09 pm

2 stops8h 57m

$406

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Wed 6/24

6:34 pm-10:31 pm

1 stop4h 57m

Des Moines

Wed 7/1

2:45 pm-11:22 pm

1 stop7h 37m

$433

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Tue 7/7

2:47 pm-10:04 pm

1 stop8h 17m

Des Moines

Thu 7/9

6:11 am-3:09 pm

2 stops7h 58m

$442

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Thu 7/30

5:10 pm-11:35 pm

1 stop7h 25m

Des Moines

Sun 8/2

4:15 pm-11:20 pm

1 stop6h 05m

$456

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Mon 11/2

7:00 am-7:25 pm

3 stops13h 25m

Des Moines

Fri 11/6

1:45 pm-11:08 pm

1 stop8h 23m

$461
Quickest round-trip

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Thu 9/24

8:45 am-2:15 pm

1 stop6h 30m

Des Moines

Sun 9/27

6:00 am-1:01 pm

1 stop6h 01m

$470

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Mon 7/13

11:40 am-10:25 pm

2 stops11h 45m

Des Moines

Tue 7/14

5:20 am-4:40 pm

2 stops10h 20m

$477

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Thu 7/30

5:10 pm-11:35 pm

1 stop7h 25m

Des Moines

Mon 8/3

5:10 am-4:30 pm

2 stops10h 20m

$478

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Fort Myers to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Des Moines in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Fort Myers-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Fort Myers-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Des Moines

What is the cheapest month to book a flight from Fort Myers to Des Moines?

Currently, December is the cheapest month in which you can book a flight from Fort Myers to Des Moines (average of $148). Flying from Fort Myers to Des Moines in March is currently the most expensive (average of $499). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Fort Myers to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 12, 2026.
Peruse reviews from past customers who have flown with Delta,Allegiant Air, andAmerican Airlines from Fort Myers to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,399 reviews

Boarding

8.1

Comfort

7.8

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,399 reviews
Delta
7.9
Good
8,399 reviews

Boarding

8.1

Comfort

7.8

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Allegiant Air
7.3
Good
703 reviews
Delta
7.9
Good
8,399 reviews

Boarding

8.1

Comfort

7.8

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.1
Good
11,644 reviews
Delta
7.9
Good
8,399 reviews

Boarding

8.1

Comfort

7.8

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Fort Myers to Des Moines?

    There are many flights that can get you from Fort Myers to Des Moines in 6h 33m. Fly via Delta or American Airlines to get the fastest option. The distance between Fort Myers and Des Moines is about 1237 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Fort Myers to Des Moines round-trip?

    Allegiant Air, at $100, was found to be the cheapest airline from Fort Myers to Des Moines.Alternate airlines to your destination round-trip include Delta and American Airlines. You may be able to fly from Fort Myers to Des Moines for 71% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Fort Myers to Des Moines one-way?

    $53 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $118 and $118, respectively.

  • Can I find deals for flights from Fort Myers to Des Moines that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Des Moines.

  • Can I find deals for business class flights from Fort Myers to Des Moines?

    Yes. Cheapflights offers flight deals from Fort Myers to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Des Moines?

    Currently, December is the cheapest month in which you can book a flight from Fort Myers to Des Moines (average of $148). Flying from Fort Myers to Des Moines in March is currently the most expensive (average of $499). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Clive
Boone
West Des Moines
Ankeny

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Top 3 airlines flying from Fort Myers to Des Moines

Discover the top 3 airlines that operate flights from Fort Myers to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$100Average$200FlexibilityNo cancel feeOn-time88%
DeltaCheapest$152Average$428FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$364FlexibilityNo cancel feeOn-time71%

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