$177+ Cheap flights from Buffalo to Des Moines (BUF - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — DSM
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Des Moines
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Best
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Cheapest flights from Buffalo to Des MoinesExplore the most affordable flight options available from Buffalo to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from Buffalo to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:10 am
BUF
- DSM
1 stop7h 21m
American Airlines
Thu 9/246:00 am
DSM
- BUF
1 stop7h 26m
American Airlines
Deal found 6/8![American Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:54 pm
BUF
- DSM
1 stop5h 55m
Delta
Tue 7/2810:25 am
DSM
- BUF
1 stop3h 48m
Delta
Deal found 6/8![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:50 am
BUF
- DSM
1 stop4h 21m
United Airlines
Tue 11/176:15 am
DSM
- BUF
2 stops6h 31m
United Airlines
Deal found 6/4![United Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:45 pm
BUF
- DSM
2 stops10h 20m
Southwest
Tue 11/176:00 am
DSM
- BUF
2 stops8h 10m
Southwest
Deal found 6/4![Southwest logo]()
$366
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:45 am
BUF
- DSM
1 stop8h 35m
United Airlines
Wed 10/73:11 pm
DSM
- BUF
1 stop4h 36m
United Airlines
Deal found 6/8![United Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:54 pm
BUF
- DSM
1 stop5h 55m
Delta
Fri 7/245:32 pm
DSM
- BUF
1 stop5h 26m
Delta
Deal found 6/8![Delta logo]()
$381
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:20 am
BUF
- DSM
1 stop8h 14m
American Airlines
Thu 7/95:00 am
DSM
- BUF
2 stops8h 19m
American Airlines
Deal found 6/5![American Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:29 am
BUF
- DSM
1 stop4h 16m
Delta
Wed 7/296:00 am
DSM
- BUF
1 stop4h 22m
Delta
Deal found 6/8![Delta logo]()
$391
Best flights from Buffalo to Des MoinesDiscover carefully curated flight deals from Buffalo to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from Buffalo to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:30 am
BUF
- DSM
1 stop8h 44m
United Airlines
Tue 11/178:00 am
DSM
- BUF
1 stop4h 10m
United Airlines
Deal found 6/4![United Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:45 pm
BUF
- DSM
2 stops10h 20m
Southwest
Tue 11/176:00 am
DSM
- BUF
2 stops8h 10m
Southwest
Deal found 6/4![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:29 am
BUF
- DSM
1 stop4h 16m
Delta
Fri 7/245:32 pm
DSM
- BUF
1 stop5h 26m
Delta
Deal found 6/8![Delta logo]()
$381
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:32 am
BUF
- DSM
1 stop7h 32m
American Airlines
Mon 7/201:04 pm
DSM
- BUF
2 stops7h 51m
American Airlines
Deal found 6/4![American Airlines logo]()
$440
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:45 am
BUF
- DSM
1 stop8h 35m
United Airlines
Wed 10/73:11 pm
DSM
- BUF
1 stop4h 36m
United Airlines
Deal found 6/8![United Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:29 am
BUF
- DSM
1 stop4h 16m
Delta
Sun 7/265:32 pm
DSM
- BUF
1 stop5h 26m
Delta
Deal found 6/8![Delta logo]()
$391
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:55 pm
BUF
- DSM
1 stop4h 40m
Southwest
Mon 7/275:10 am
DSM
- BUF
1 stop4h 15m
Southwest
Deal found 6/7![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:29 am
BUF
- DSM
1 stop4h 16m
Delta
Mon 7/206:00 am
DSM
- BUF
1 stop4h 22m
Delta
Deal found 6/8![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:55 pm
BUF
- DSM
1 stop4h 40m
Southwest
Sun 7/195:10 am
DSM
- BUF
2 stops8h 15m
Southwest
Deal found 6/5![Southwest logo]()
$432
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:04 pm
BUF
- DSM
1 stop4h 18m
United Airlines
Tue 7/286:00 am
DSM
- BUF
2 stops7h 25m
United Airlines
Deal found 6/8![United Airlines logo]()
$440
Last-minute flights from Buffalo to Des MoinesDiscover last-minute flight deals from Buffalo to Des Moines. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Des Moines. Data last updated June 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:20 am
BUF
- DSM
1 stop8h 14m
American Airlines
Thu 7/95:00 am
DSM
- BUF
2 stops8h 19m
American Airlines
Deal found 6/5![American Airlines logo]()
$386
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:55 pm
BUF
- DSM
1 stop4h 40m
Southwest
Sun 7/195:10 am
DSM
- BUF
2 stops8h 15m
Southwest
Deal found 6/5![Southwest logo]()
$432
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:29 am
BUF
- DSM
1 stop4h 16m
Delta
Mon 7/206:00 am
DSM
- BUF
1 stop4h 22m
Delta
Deal found 6/8![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:55 pm
BUF
- DSM
1 stop4h 40m
Southwest
Mon 7/274:40 pm
DSM
- BUF
2 stops6h 35m
Southwest
Deal found 6/5![Southwest logo]()
$412
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:54 pm
BUF
- DSM
1 stop5h 55m
Delta
Tue 7/2810:25 am
DSM
- BUF
1 stop3h 48m
Delta
Deal found 6/8![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:54 pm
BUF
- DSM
1 stop5h 55m
Delta
Fri 7/245:32 pm
DSM
- BUF
1 stop5h 26m
Delta
Deal found 6/8![Delta logo]()
$381
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:29 am
BUF
- DSM
1 stop4h 16m
Delta
Wed 7/296:00 am
DSM
- BUF
1 stop4h 22m
Delta
Deal found 6/8![Delta logo]()
$391
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:29 am
BUF
- DSM
1 stop4h 16m
Delta
Fri 7/245:32 pm
DSM
- BUF
1 stop5h 26m
Delta
Deal found 6/8![Delta logo]()
$417
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:29 am
BUF
- DSM
1 stop4h 16m
Delta
Sun 7/265:32 pm
DSM
- BUF
1 stop5h 26m
Delta
Deal found 6/8![Delta logo]()
$427
This CheapTicketsDeal deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapTicketsDeal is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:02 pm
BUF
- DSM
1 stop4h 40m
Undisclosed Carrier
Thu 7/305:17 am
DSM
- BUF
1 stop4h 15m
Undisclosed Carrier
Deal found 6/7![Undisclosed Carrier logo]()
$430
One-way flights from Buffalo to Des MoinesSearch for one-way flight options from Buffalo to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from Buffalo to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:48 pm
BUF
- DSM
2 stops31h 39m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$177
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:54 pm
BUF
- DSM
1 stop4h 14m
United Airlines
Deal found 6/8![United Airlines logo]()
$178
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:51 am
BUF
- DSM
2 stops8h 12m
American Airlines
Deal found 6/9![American Airlines logo]()
$183
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:59 am
BUF
- DSM
1 stop7h 00m
American Airlines
Deal found 6/5![American Airlines logo]()
$190
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:29 am
BUF
- DSM
1 stop4h 16m
Delta
Deal found 6/8![Delta logo]()
$204
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:20 am
BUF
- DSM
2 stops8h 43m
American Airlines
Deal found 6/8![American Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:32 am
BUF
- DSM
1 stop7h 33m
American Airlines
Deal found 6/6![American Airlines logo]()
$214
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:34 am
BUF
- DSM
2 stops11h 48m
United Airlines
Deal found 6/9![United Airlines logo]()
$219
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:04 pm
BUF
- DSM
1 stop4h 18m
United Airlines
Deal found 6/8![United Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:32 am
BUF
- DSM
1 stop7h 33m
American Airlines
Deal found 6/6![American Airlines logo]()
$232
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1612:40 pm
BUF
- DSM
2 stops11h 55m
Southwest
Deal found 6/5![Southwest logo]()
$243
Find flight deals from Buffalo to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $317 (American Airlines) |
One-way from | $177 (Kiwi.com) |
Popular in | March |
Cheapest in | April |
Average price | $438 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Buffalo to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Tue 11/10
8:30 am-4:14 pm
1 stop8h 44m
Des Moines
Tue 11/17
8:00 am-1:10 pm
1 stop4h 10m
$355
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Tue 11/10
12:45 pm-10:05 pm
2 stops10h 20m
Des Moines
Tue 11/17
6:00 am-3:10 pm
2 stops8h 10m
$366
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Tue 10/6
8:45 am-4:20 pm
1 stop8h 35m
Des Moines
Wed 10/7
3:11 pm-8:47 pm
1 stop4h 36m
$370
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Wed 7/22
6:29 am-9:45 am
1 stop4h 16m
Des Moines
Fri 7/24
5:32 pm-11:58 pm
1 stop5h 26m
$381
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Wed 7/22
6:29 am-9:45 am
1 stop4h 16m
Des Moines
Sun 7/26
5:32 pm-11:58 pm
1 stop5h 26m
$391
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Mon 7/20
7:55 pm-11:35 pm
1 stop4h 40m
Des Moines
Mon 7/27
5:10 am-10:25 am
1 stop4h 15m
$407
Quickest round-trip
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Fri 7/17
6:29 am-9:45 am
1 stop4h 16m
Des Moines
Mon 7/20
6:00 am-11:22 am
1 stop4h 22m
$407
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Thu 7/16
7:55 pm-11:35 pm
1 stop4h 40m
Des Moines
Sun 7/19
5:10 am-2:25 pm
2 stops8h 15m
$432
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Fri 7/17
6:32 am-1:04 pm
1 stop7h 32m
Des Moines
Mon 7/20
1:04 pm-9:55 pm
2 stops7h 51m
$440
BuffaloDes Moines
BUF - DSM
BUFDSM
Buffalo
Tue 7/21
6:04 pm-9:22 pm
1 stop4h 18m
Des Moines
Tue 7/28
6:00 am-2:25 pm
2 stops7h 25m
$440
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Buffalo to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Des Moines in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Buffalo with our price prediction graph.
BUF-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 9, 2026.
Read through reviews of airlines operating flights from Buffalo to Des Moines, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 9, 2026.
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Buffalo and Des Moines flights
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Top 2 airlines flying from Buffalo to Des Moines
Discover the top 2 airlines that operate flights from Buffalo to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$427 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$319 | Average$479 | FlexibilityNo cancel fee | On-timeN/A |