$119+ Cheap flights from Mesa, AZ to Buffalo (BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — BUF
Jul 13 — Jul 201
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Buffalo are usually found in March or February, booked 71 days in advance, depart on a Monday or Thursday and return on a Friday
Cheap flight deals from Mesa to Buffalo
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Cheapest flights from Mesa to BuffaloExplore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.
Explore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/313:28 pm
PHX
- BUF
1 stop5h 30m
Delta
Thu 8/63:53 pm
BUF
- PHX
1 stop10h 44m
Delta
Deal found 6/10![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:05 pm
PHX
- BUF
1 stop9h 35m
Southwest
Sat 9/1210:50 am
BUF
- PHX
2 stops8h 40m
Southwest
Deal found 6/10![Southwest logo]()
$269
This Frontier deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:35 pm
PHX
- BUF
1 stop8h 05m
Frontier
Sat 9/121:16 pm
BUF
- PHX
1 stop11h 23m
Frontier
Deal found 6/11![Frontier logo]()
$271
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:45 am
PHX
- BUF
1 stop6h 05m
Southwest
Sun 11/84:00 pm
BUF
- PHX
1 stop10h 35m
Southwest
Deal found 6/10![Southwest logo]()
$272
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Wed 7/292:48 pm
BUF
- PHX
1 stop7h 56m
Frontier
Deal found 6/10![Frontier logo]()
$273
This Frontier deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2711:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Mon 8/32:48 pm
BUF
- PHX
1 stop7h 56m
Frontier
Deal found 6/11![Frontier logo]()
$274
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1011:23 pm
PHX
- BUF
1 stop9h 10m
Frontier
Tue 7/149:09 pm
BUF
- PHX
1 stop16h 21m
Frontier
Deal found 6/11![Frontier logo]()
$275
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:10 pm
PHX
- BUF
1 stop11h 45m
Southwest
Tue 10/208:35 am
BUF
- PHX
2 stops7h 45m
Southwest
Deal found 6/11![Southwest logo]()
$277
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:29 am
PHX
- BUF
1 stop10h 11m
Delta
Fri 9/113:50 pm
BUF
- PHX
1 stop9h 24m
Delta
Deal found 6/11![Delta logo]()
$278
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:25 am
PHX
- BUF
2 stops8h 50m
Southwest
Mon 10/55:45 pm
BUF
- PHX
1 stop9h 20m
Southwest
Deal found 6/10![Southwest logo]()
$279
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:12 am
PHX
- BUF
1 stop13h 20m
Frontier
Thu 7/169:29 pm
BUF
- PHX
1 stop16h 01m
Frontier
Deal found 6/12![Frontier logo]()
$281
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2412:35 am
PHX
- BUF
1 stop15h 37m
Frontier
Wed 7/17:57 pm
BUF
- PHX
1 stop17h 30m
Frontier
Deal found 6/10![Frontier logo]()
$283
Best flights from Mesa to BuffaloDiscover carefully curated flight deals from Mesa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 13, 2026.
Discover carefully curated flight deals from Mesa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 13, 2026.
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:00 am
PHX
- BUF
1 stop7h 25m
Southwest
Sun 11/84:00 pm
BUF
- PHX
1 stop10h 35m
Southwest
Deal found 6/10![Southwest logo]()
$290
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:06 am
PHX
- BUF
2 stops9h 52m
United Airlines
Tue 8/46:04 pm
BUF
- PHX
1 stop7h 23m
United Airlines
Deal found 6/9![United Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:15 pm
PHX
- BUF
1 stop12h 10m
Southwest
Mon 8/36:25 am
BUF
- PHX
1 stop9h 35m
Southwest
Deal found 6/8![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:00 am
PHX
- BUF
1 stop9h 07m
United Airlines
Sat 8/226:55 am
BUF
- PHX
2 stops14h 05m
United Airlines
Deal found 6/8![United Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:00 am
PHX
- BUF
2 stops9h 15m
Southwest
Mon 10/2611:55 am
BUF
- PHX
2 stops10h 15m
Southwest
Deal found 6/8![Southwest logo]()
$328
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:20 am
PHX
- BUF
1 stop7h 36m
United Airlines
Sat 9/510:30 am
BUF
- PHX
2 stops9h 40m
United Airlines
Deal found 6/8![United Airlines logo]()
$342
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/249:45 am
PHX
- BUF
1 stop9h 55m
United Airlines
Sat 6/2710:57 am
BUF
- PHX
1 stop7h 17m
United Airlines
Deal found 6/9![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:55 am
PHX
- BUF
2 stops9h 10m
Southwest
Tue 8/188:55 am
BUF
- PHX
2 stops9h 10m
Southwest
Deal found 6/9![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:15 pm
PHX
- BUF
1 stop12h 05m
Southwest
Tue 7/142:55 pm
BUF
- PHX
2 stops9h 05m
Southwest
Deal found 6/11![Southwest logo]()
$359
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:05 am
PHX
- BUF
2 stops7h 55m
Southwest
Thu 7/306:05 am
BUF
- PHX
2 stops16h 35m
Southwest
Deal found 6/10![Southwest logo]()
$415
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:25 am
PHX
- BUF
1 stop6h 25m
Southwest
Sat 8/16:25 pm
BUF
- PHX
Nonstop4h 35m
Southwest
Deal found 6/12![Southwest logo]()
$447
Last-minute flights from Mesa to BuffaloDiscover last-minute flight deals from Mesa to Buffalo. Data last updated June 13, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Buffalo. Data last updated June 13, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:35 am
PHX
- BUF
1 stop15h 37m
Frontier
Tue 6/239:02 pm
BUF
- PHX
1 stop16h 25m
Frontier
Deal found 6/9![Frontier logo]()
$287
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2212:35 am
PHX
- BUF
1 stop15h 37m
Frontier
Tue 6/309:02 pm
BUF
- PHX
1 stop16h 25m
Frontier
Deal found 6/10![Frontier logo]()
$295
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2412:35 am
PHX
- BUF
1 stop15h 37m
Frontier
Wed 7/17:57 pm
BUF
- PHX
1 stop17h 30m
Frontier
Deal found 6/10![Frontier logo]()
$283
This CheapOair deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:40 pm
PHX
- BUF
1 stop8h 54m
Frontier
Mon 7/137:57 pm
BUF
- PHX
1 stop17h 33m
Frontier
Deal found 6/13![Frontier logo]()
$284
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1011:23 pm
PHX
- BUF
1 stop9h 10m
Frontier
Tue 7/149:09 pm
BUF
- PHX
1 stop16h 21m
Frontier
Deal found 6/11![Frontier logo]()
$275
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:12 am
PHX
- BUF
1 stop13h 20m
Frontier
Thu 7/169:29 pm
BUF
- PHX
1 stop16h 01m
Frontier
Deal found 6/12![Frontier logo]()
$281
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Wed 7/292:48 pm
BUF
- PHX
1 stop7h 56m
Frontier
Deal found 6/10![Frontier logo]()
$273
This Frontier deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2711:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Mon 8/32:48 pm
BUF
- PHX
1 stop7h 56m
Frontier
Deal found 6/11![Frontier logo]()
$274
This Trip.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2712:12 am
PHX
- BUF
1 stop15h 54m
Frontier
Thu 8/69:33 pm
BUF
- PHX
1 stop15h 57m
Frontier
Deal found 6/12![Frontier logo]()
$293
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:02 pm
PHX
- BUF
1 stop9h 14m
American Airlines
Thu 7/306:01 am
BUF
- PHX
1 stop8h 03m
American Airlines
Deal found 6/11![American Airlines logo]()
$297
This Frontier deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:12 am
PHX
- BUF
1 stop13h 20m
Frontier
Sat 8/112:28 pm
BUF
- PHX
1 stop10h 09m
Frontier
Deal found 6/11![Frontier logo]()
$305
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/313:28 pm
PHX
- BUF
1 stop5h 30m
Delta
Thu 8/63:53 pm
BUF
- PHX
1 stop10h 44m
Delta
Deal found 6/10![Delta logo]()
$267
One-way flights from Mesa to BuffaloSearch for one-way flight options from Mesa to Buffalo. Find affordable one-way fares based on user searches. Data last updated June 13, 2026.
Search for one-way flight options from Mesa to Buffalo. Find affordable one-way fares based on user searches. Data last updated June 13, 2026.
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:05 pm
PHX
- BUF
1 stop6h 10m
Delta
Deal found 6/11![Delta logo]()
$119
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/411:40 pm
PHX
- BUF
1 stop7h 49m
Frontier
Deal found 6/10![Frontier logo]()
$120
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/812:12 am
PHX
- BUF
1 stop13h 20m
Frontier
Deal found 6/10![Frontier logo]()
$126
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2011:40 pm
PHX
- BUF
1 stop8h 00m
Frontier
Deal found 6/10![Frontier logo]()
$131
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:30 am
PHX
- BUF
2 stops7h 30m
Southwest
Deal found 6/11![Southwest logo]()
$135
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/711:29 am
PHX
- BUF
1 stop10h 11m
Delta
Deal found 6/11![Delta logo]()
$136
This Expedia deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2012:35 am
PHX
- BUF
1 stop15h 37m
Frontier
Deal found 6/12![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:04 am
PHX
- BUF
2 stops25h 49m
Frontier
Deal found 6/11![Frontier logo]()
$146
This Booking.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2212:35 am
PHX
- BUF
1 stop15h 37m
Frontier
Deal found 6/9![Frontier logo]()
$148
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:28 pm
PHX
- BUF
1 stop5h 30m
Delta
Deal found 6/8![Delta logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/59:04 am
PHX
- BUF
2 stops22h 25m
Frontier
Deal found 6/10![Frontier logo]()
$150
Find flight deals from Mesa to Buffalo
Keep the following information in mind while searching for Mesa to Buffalo flight deals. Data was last updated June 13, 2026.
Round-trip from | $267 (Delta) |
|---|---|
One-way from | $119 (Delta) |
Popular in | November |
Cheapest in | March |
Average price | $398 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
Use the filters below to find and compare flights from Mesa to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Fri 11/6
5:00 am-2:25 pm
1 stop7h 25m
Buffalo
Sun 11/8
4:00 pm-12:35 am
1 stop10h 35m
$290
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Thu 7/30
7:15 pm-10:25 am
1 stop12h 10m
Buffalo
Mon 8/3
6:25 am-1:00 pm
1 stop9h 35m
$323
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Fri 10/23
7:00 am-7:15 pm
2 stops9h 15m
Buffalo
Mon 10/26
11:55 am-7:10 pm
2 stops10h 15m
$328
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 7/28
10:06 am-10:58 pm
2 stops9h 52m
Buffalo
Tue 8/4
6:04 pm-10:27 pm
1 stop7h 23m
$341
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 8/18
9:00 am-9:07 pm
1 stop9h 07m
Buffalo
Sat 8/22
6:55 am-6:00 pm
2 stops14h 05m
$342
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Sat 8/29
6:20 am-4:56 pm
1 stop7h 36m
Buffalo
Sat 9/5
10:30 am-5:10 pm
2 stops9h 40m
$342
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Wed 6/24
9:45 am-10:40 pm
1 stop9h 55m
Buffalo
Sat 6/27
10:57 am-3:14 pm
1 stop7h 17m
$348
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 8/11
8:55 am-9:05 pm
2 stops9h 10m
Buffalo
Tue 8/18
8:55 am-3:05 pm
2 stops9h 10m
$349
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Fri 7/10
7:15 pm-10:20 am
1 stop12h 05m
Buffalo
Tue 7/14
2:55 pm-9:00 pm
2 stops9h 05m
$359
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 7/28
9:05 am-8:00 pm
2 stops7h 55m
Buffalo
Thu 7/30
6:05 am-7:40 pm
2 stops16h 35m
$415
Showing 1-10 of 23 resultsSorted by cheapest first
Best time to book a flight from Mesa to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mesa with our price prediction graph.
PHX-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Buffalo
MS9-BUF
PHX-BUF
What is the cheapest time of day to fly from MS9 to BUF?
Find hourly flight availability from Mesa to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 13, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Buffalo as you normally would.
How much does it cost to fly round-trip from Mesa to Buffalo?
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated June 13, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Mesa to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Mesa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
Batavia
Williamsville
Orchard Park
Eden
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Mesa to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 13, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mesa to Buffalo by cabin class
Find flights from Mesa to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mesa and Buffalo flights
Browse other Mesa and Buffalo flight options. Last updated on June 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mesa to Buffalo flights
Consider these flights traveling from Mesa to Buffalo.
Top 6 airlines flying from Mesa to Buffalo
Discover the top 6 airlines that operate flights from Mesa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$125 | Average$310 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$148 | Average$337 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$198 | Average$324 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$236 | Average$366 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$262 | Average$462 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$296 | Average$438 | FlexibilityNo cancel fee | On-time71% |