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Cheap flights from Des Moines to St. Louis (DSM - STL) from $135

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — STL
Jun 4 — Jun 111
From?
To?
Tue 6/4
Tue 6/11
1 adult, Economy
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Cheap flight deals from Des Moines to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 30, 2024.

Popular in

February

Cheapest in

November

Round-trip from

$319

One-way from

$135
High demand for flights, 31% potential price rise
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Best time to find cheap flights, 43% potential price drop
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From Des Moines to Lambert-St Louis
Search Deals
One-way flight from Des Moines to Lambert-St Louis
Search Deals

What is the cheapest day to fly round-trip from Des Moines to St. Louis?

Flights from Des Moines to St. Louis are found to be more expensive on Monday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to St. Louis.

What is the cheapest month to fly from Des Moines to St. Louis?

Flights from Des Moines to St. Louis lean towards being more expensive in February. Prices are generally better when you fly from Des Moines to St. Louis in November, with the cheapest ticket starting at $198.

What is the cheapest time of day to fly from DSM to STL?

One of the essential ways to save on airfare from Des Moines to St. Louis is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 40% on airfare.

Cheap Delta flights from Des Moines to St. Louis

Explore cheap flight options specifically provided by Delta for the route between Des Moines and St. Louis. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,784,634 searches. Data last updated May 30, 2024.
Consider these cheap Delta flights we've found departing from Des Moines to St. Louis. Deals update often to give you more flight options matching your criteria
Fri 8/236:29 pmDSM - STL
1 stop5h 10mDelta
Sun 8/256:06 amSTL - DSM
1 stop5h 06mDelta
Deal found 5/29$212
Mon 8/56:29 pmDSM - STL
1 stop5h 10mDelta
Wed 8/76:06 amSTL - DSM
1 stop5h 06mDelta
Deal found 5/29$253
Fri 8/236:29 pmDSM - STL
1 stop5h 10mDelta
Sun 8/256:30 amSTL - DSM
2 stops10h 14mDelta
Deal found 5/29$339
Thu 6/206:32 amDSM - STL
1 stop6h 54mDelta
Sun 6/236:06 amSTL - DSM
1 stop5h 07mDelta
Deal found 5/30$350
Thu 7/186:35 amDSM - STL
2 stops9h 45mDelta
Mon 7/225:26 pmSTL - DSM
1 stop4h 53mDelta
Deal found 5/30$431
Fri 8/2311:52 amDSM - STL
2 stops8h 44mDelta
Sun 8/256:30 amSTL - DSM
2 stops10h 14mDelta
Deal found 5/29$500
Mon 9/1612:20 pmDSM - STL
2 stops8h 11mDelta
Fri 9/2011:51 amSTL - DSM
1 stop6h 00mDelta
Deal found 5/30$583
Thu 7/186:35 amDSM - STL
2 stops9h 45mDelta
Mon 7/2211:28 amSTL - DSM
2 stops9h 37mDelta
Deal found 5/30$587
Tue 6/47:05 amDSM - STL
2 stops6h 03mDelta
Thu 6/66:11 amSTL - DSM
1 stop5h 07mDelta
Deal found 5/29$603

Cheap American Airlines flights from Des Moines to St. Louis

Explore cheap flight options specifically provided by American Airlines for the route between Des Moines and St. Louis. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,784,634 searches. Data last updated May 30, 2024.
Browse through some of the cheapest American Airlines flights traveling from Des Moines to St. Louis. If these deals don't fit your criteria, make sure to check back soon as new deals are always added.
Tue 8/612:02 pmDSM - STL
1 stop3h 30mAmerican Airlines
Thu 8/84:22 pmSTL - DSM
1 stop5h 57mAmerican Airlines
Deal found 5/30$213
Tue 6/412:23 pmDSM - STL
1 stop7h 07mAmerican Airlines
Thu 6/65:38 pmSTL - DSM
1 stop6h 27mAmerican Airlines
Deal found 5/29$463
Tue 8/67:02 amDSM - STL
2 stops12h 45mAmerican Airlines
Thu 8/84:22 pmSTL - DSM
1 stop5h 57mAmerican Airlines
Deal found 5/30$526
Thu 6/205:54 amDSM - STL
2 stops13h 35mAmerican Airlines
Sun 6/236:00 amSTL - DSM
1 stop3h 29mAmerican Airlines
Deal found 5/30$580
Tue 6/46:40 amDSM - STL
2 stops9h 37mAmerican Airlines
Thu 6/66:00 amSTL - DSM
2 stops9h 17mAmerican Airlines
Deal found 5/29$1,520

Cheap Des Moines to St. Louis flights in May & June 2024

Find cheap flight options from Des Moines to St. Louis specifically for the months of May and June 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,784,634 searches. Prices were last updated on May 30, 2024.
These are some of the best deals we've found on flights to St. Louis in 2024 at this time. For more flight deals, be sure to check back very soon.
Thu 6/206:32 amDSM - STL
1 stop6h 54mDelta
Sun 6/236:06 amSTL - DSM
1 stop5h 07mDelta
Deal found 5/30$350
Tue 6/412:23 pmDSM - STL
1 stop7h 07mAmerican Airlines
Thu 6/65:38 pmSTL - DSM
1 stop6h 27mAmerican Airlines
Deal found 5/29$463
Fri 5/3111:40 amDSM - STL
1 stop7h 48mAmerican Airlines
Tue 6/45:04 amSTL - DSM
1 stop6h 34mAmerican Airlines
Deal found 5/29$465
Fri 5/319:00 amDSM - STL
2 stops7h 05mMultiple Airlines
Wed 6/51:55 pmSTL - DSM
2 stops24h 57mMultiple Airlines
Deal found 5/28$476
Fri 5/319:00 amDSM - STL
2 stops7h 05mMultiple Airlines
Wed 6/512:15 pmSTL - DSM
3 stops26h 37mMultiple Airlines
Deal found 5/28$485
Thu 6/201:14 pmDSM - STL
3 stops25h 02mMultiple Airlines
Sun 6/235:22 pmSTL - DSM
1 stop16h 37mMultiple Airlines
Deal found 5/30$511
Thu 6/201:14 pmDSM - STL
3 stops25h 02mMultiple Airlines
Sun 6/236:15 pmSTL - DSM
2 stops21h 18mMultiple Airlines
Deal found 5/30$514
Thu 6/205:54 amDSM - STL
2 stops13h 35mAmerican Airlines
Sun 6/236:00 amSTL - DSM
1 stop3h 29mAmerican Airlines
Deal found 5/30$580
Tue 6/47:05 amDSM - STL
2 stops6h 03mDelta
Thu 6/66:11 amSTL - DSM
1 stop5h 07mDelta
Deal found 5/29$603

Des Moines to St. Louis 2024 flight deals

Discover exclusive flight deals for travel between Des Moines and St. Louis in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,784,634 searches. Data last updated May 30, 2024.
These are some of the best deals we've found on flights to St. Louis in 2024 at this time. For more flight deals, be sure to check back very soon.
Fri 8/236:29 pmDSM - STL
1 stop5h 10mDelta
Sun 8/256:06 amSTL - DSM
1 stop5h 06mDelta
Deal found 5/29$212
Tue 8/612:02 pmDSM - STL
1 stop3h 30mAmerican Airlines
Thu 8/84:22 pmSTL - DSM
1 stop5h 57mAmerican Airlines
Deal found 5/30$213
Mon 8/56:29 pmDSM - STL
1 stop5h 10mDelta
Wed 8/76:06 amSTL - DSM
1 stop5h 06mDelta
Deal found 5/29$253
Thu 7/182:25 pmDSM - STL
1 stop19h 00mFrontier
Mon 7/227:33 pmSTL - DSM
1 stop22h 11mFrontier
Deal found 5/30$258
Thu 7/184:08 pmDSM - STL
1 stop16h 28mFrontier
Mon 7/227:33 pmSTL - DSM
1 stop22h 11mFrontier
Deal found 5/30$268
Fri 8/236:29 pmDSM - STL
1 stop5h 10mDelta
Sun 8/256:30 amSTL - DSM
2 stops10h 14mDelta
Deal found 5/29$339
Thu 6/206:32 amDSM - STL
1 stop6h 54mDelta
Sun 6/236:06 amSTL - DSM
1 stop5h 07mDelta
Deal found 5/30$350
Thu 7/186:35 amDSM - STL
2 stops9h 45mDelta
Mon 7/225:26 pmSTL - DSM
1 stop4h 53mDelta
Deal found 5/30$431
Tue 6/412:23 pmDSM - STL
1 stop7h 07mAmerican Airlines
Thu 6/65:38 pmSTL - DSM
1 stop6h 27mAmerican Airlines
Deal found 5/29$463

Des Moines to St. Louis flights leaving soon

Find last-minute flight options from Des Moines to St. Louis for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 2,784,634 searches. Data last updated May 30, 2024.
Check out these flights departing soon from Des Moines to St. Louis. To prevent any unwanted surprises, users should verify their flight info before booking.
Tue 6/412:23 pmDSM - STL
1 stop7h 07mAmerican Airlines
Thu 6/65:38 pmSTL - DSM
1 stop6h 27mAmerican Airlines
Deal found 5/29$463
Tue 6/47:05 amDSM - STL
2 stops6h 03mDelta
Thu 6/66:11 amSTL - DSM
1 stop5h 07mDelta
Deal found 5/29$603
Tue 6/46:40 amDSM - STL
2 stops9h 37mAmerican Airlines
Thu 6/66:00 amSTL - DSM
2 stops9h 17mAmerican Airlines
Deal found 5/29$1,520

One-way flights to St. Louis from Des Moines

Search for one-way flight options from Des Moines to St. Louis. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 2,784,634 searches. Data last updated May 30, 2024.
Take a look at some of the one-way flights we've detected from Des Moines to St. Louis. Users needing a return flight from Des Moines to St. Louis should utilize the search form above.
Thu 6/276:57 pmDSM - STL
1 stop12h 10mFrontier
Deal found 5/28$135
Wed 6/55:33 amDSM - STL
1 stop6h 15mDelta
Deal found 5/29$186
Sat 6/84:00 pmDSM - STL
1 stop5h 55mDelta
Deal found 5/29$187
Fri 6/76:40 amDSM - STL
2 stops9h 25mMultiple Airlines
Deal found 5/29$205
Tue 6/412:23 pmDSM - STL
1 stop7h 07mAmerican Airlines
Deal found 5/29$232
Fri 6/76:40 amDSM - STL
3 stops34h 48mMultiple Airlines
Deal found 5/29$257
Thu 6/277:30 amDSM - STL
3 stops29h 10mMultiple Airlines
Deal found 5/28$281
Thu 6/273:59 pmDSM - STL
2 stops20h 41mMultiple Airlines
Deal found 5/28$307
Sat 6/85:14 pmDSM - STL
2 stops21h 02mUnited Airlines
Deal found 5/29$312

Find flights from Des Moines to St. Louis within your budget

Customize your flight search to find flights from Des Moines to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,784,634 searches. Data last updated May 30, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$212 - $526

Route

Depart

Return

Price

Des MoinesLambert-St Louis

DSM - STL

DSMSTL

Des Moines

Fri 8/23

1 stop5h 10m

Lambert-St Louis

Sun 8/25

1 stop5h 06m

$212

Des MoinesLambert-St Louis

DSM - STL

DSMSTL

Des Moines

Tue 8/6

1 stop3h 30m

Lambert-St Louis

Thu 8/8

1 stop5h 57m

$213

Des MoinesLambert-St Louis

DSM - STL

DSMSTL

Des Moines

Mon 8/5

1 stop5h 10m

Lambert-St Louis

Wed 8/7

1 stop5h 06m

$253

Des MoinesLambert-St Louis

DSM - STL

DSMSTL

Des Moines

Thu 7/18

1 stop19h 00m

Lambert-St Louis

Mon 7/22

1 stop22h 11m

$258

Des MoinesLambert-St Louis

DSM - STL

DSMSTL

Des Moines

Fri 8/23

1 stop5h 10m

Lambert-St Louis

Sun 8/25

2 stops10h 14m

$339

Des MoinesLambert-St Louis

DSM - STL

DSMSTL

Des Moines

Thu 6/20

1 stop6h 54m

Lambert-St Louis

Sun 6/23

1 stop5h 07m

$350

Des MoinesLambert-St Louis

DSM - STL

DSMSTL

Des Moines

Thu 6/20

3 stops25h 02m

Lambert-St Louis

Sun 6/23

1 stop16h 37m

$511

Des MoinesLambert-St Louis

DSM - STL

DSMSTL

Des Moines

Thu 6/20

3 stops25h 02m

Lambert-St Louis

Sun 6/23

2 stops21h 18m

$514

Des MoinesLambert-St Louis

DSM - STL

DSMSTL

Des Moines

Tue 8/6

2 stops12h 45m

Lambert-St Louis

Thu 8/8

1 stop5h 57m

$526

Flights are sorted by cheapest first

Deals found on 5/29

What is the cheapest day to fly from Des Moines to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to St. Louis. Price data was last updated on May 26, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their Des Moines to St. Louis flight should consider departing on Saturday mornings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Best time to book a flight from Des Moines to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Temperature and rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature and rainfall totals by month.

STL

Temperature

32 - 80.6 °F

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated May 30, 2024.
Read reviews from past customers who have flown Delta and American Airlines from Des Moines to St. Louis. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
10,457 reviews
Check prices

Food

7.4

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

8.0

Crew

8.6

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Delta
8.0
Very good
10,457 reviews
Delta
8.0
Very good
10,457 reviews
Check prices

Food

7.4

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

8.0

Crew

8.6

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

United Airlines
7.4
Good
10,777 reviews
Delta
8.0
Very good
10,457 reviews
Check prices

Food

7.4

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

8.0

Crew

8.6

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

American Airlines
7.3
Good
14,284 reviews
Delta
8.0
Very good
10,457 reviews
Check prices

Food

7.4

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

8.0

Crew

8.6

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Frontier
6.3
Okay
4,016 reviews
Delta
8.0
Very good
10,457 reviews
Check prices

Food

7.4

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

8.0

Crew

8.6

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Des Moines to St. Louis?

    Lambert-St Louis is the airport most travelers will use when flying to St. Louis from Des Moines. Booking flights from Des Moines (DSM) to Lambert-St Louis (STL) should be relatively easy as there is 1 daily flight to St. Louis from 3 different airlines. 4h 25m is how long a flight from Des Moines to Lambert-St Louis will take if you book a nonstop flight.

  • Can I find flights from Des Moines to St. Louis for under $300 on Cheapflights?

    Yes, there are multiple flights from Des Moines to St. Louis for under $300. The cheapest flight booked recently is on Delta for just $212, but on average you can expect to pay $525.

  • Are there last-minute flights available from Des Moines to St. Louis for under $500?

    There are currently 3+ open flights from Des Moines to St. Louis within the next 7 days for less than $500.

  • What days are nonstop flights available from Des Moines to St. Louis?

    You can find nonstop flights on the following days: Saturday.

  • How many flights depart from Des Moines to St. Louis on average per day?

    Per day, 2 flights depart from Des Moines to St. Louis on average.
    Early Morning (Midnight to 6am) - 50% of flight departures
    Evening (6pm - Midnight) - 50% of flight departures

  • How long is the flight from Des Moines to St. Louis?

    A quick flight from Des Moines to St. Louis can take about 3h 30m. Delta provides one of the quickest options available for as low as $212. Airlines will cover a distance of 260 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to St. Louis round-trip?

    Cheapflights users have booked flights from Des Moines to St. Louis round-trip from $212. Other airlines that can offer you cheap pricing are American Airlines, from $213, and Frontier, from $258. Users have found that Delta is 47% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Des Moines to St. Louis one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $135. Delta flights start at $186 while deals on American Airlines start at $232 one-way.

  • What does DSM to STL mean?

    Des Moines Airport is DSM and Lambert-St Louis Airport is STL. These codes are created by the International Air Transport Association (IATA) and airlines use them to identify the departing and arrival airports in the flight routes they service.

  • Can I find deals for flights from Des Moines to St. Louis that include extra baggage allowance?

    The amount of baggage you can bring on your Des Moines to St. Louis flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Des Moines to St. Louis with specific airlines?

    Yes, Cheapflights allows you to browse and filter Des Moines to St. Louis flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Des Moines to St. Louis that include hotel bookings?

    Yes. In addition to deals on Des Moines to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to St. Louis.

  • Can I find deals for business class flights from Des Moines to St. Louis?

    Yes. Cheapflights offers flight deals from Des Moines to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Des Moines to St. Louis that allow pets onboard?

    Many airlines flying from Des Moines to St. Louis offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Des Moines to St. Louis?

    Yes, you can often find last-minute deals on Des Moines to St. Louis flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Des Moines to St. Louis flight deals updated?

    The Des Moines to St. Louis flight deals you see on this page were last updated on 5/30.

  • What are the most popular airlines that fly from Des Moines to St. Louis?

    Before booking your flight from Des Moines to St. Louis check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

  • What is the cheapest month to book a flight from Des Moines to St. Louis?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to St. Louis (average of $319). Flying from Des Moines to St. Louis in July is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.

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Top 3 airlines flying from Des Moines to St. Louis

Discover the top 3 airlines that operate flights from Des Moines to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,784,634 searches. Data last updated May 30, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$177Average$286FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
United AirlinesCheapest$211Average$311FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
American AirlinesCheapest$244Average$434FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
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Search flights from Des Moines to St. Louis by cabin class

Find flights from Des Moines to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
First Class
Business Class
Prem Econ Class
Economy Class

Hourly flight availability from Des Moines to St. Louis

Find hourly flight availability from Des Moines to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 30, 2024.
62%of flight departuresEarly morningMidnight to 6 am
0%of flight departuresMorning6 am to noon
38%of flight departuresAfternoonNoon to 6 pm
0%of flight departuresEvening6 pm to midnight
Midnight
6 AM
Noon
6 PM

Weekly flight availability from Des Moines to St. Louis

Explore weekly flight availability from Des Moines to St. Louis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 30, 2024.
Sunday2daily flights
Monday2daily flights
Tuesday2daily flights
Wednesday2daily flights
Thursday2daily flights
Friday2daily flights
Saturday1daily flight

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Des Moines to St. Louis?

Cheapflights makes it easy to find Des Moines to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Des Moines to St. Louis?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Des Moines to St. Louis for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Des Moines to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Des Moines to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Des Moines to St. Louis become cheaper?

Yes! Start tracking prices for Des Moines to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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