$132+ Cheap flights from Des Moines to San Antonio (DSM - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Jul 8 — Jul 151
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
One-way
Cheapest flights from Des Moines to San AntonioExplore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- SAT
1 stop23h 16m
Multiple Airlines
Tue 8/117:49 pm
SAT
- DSM
1 stop17h 45m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$236
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:30 pm
DSM
- SAT
1 stop5h 58m
Delta
Wed 11/1810:45 am
SAT
- DSM
1 stop6h 57m
Delta
Deal found 6/8![Delta logo]()
$263
This CheapOair deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:31 pm
DSM
- SAT
1 stop19h 41m
Frontier
Thu 10/2911:08 am
SAT
- DSM
1 stop26h 48m
Frontier
Deal found 6/4![Frontier logo]()
$268
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:54 pm
DSM
- SAT
1 stop6h 10m
Delta
Mon 8/102:43 pm
SAT
- DSM
1 stop7h 54m
Delta
Deal found 6/8![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:25 pm
DSM
- SAT
1 stop7h 00m
Southwest
Tue 8/112:35 pm
SAT
- DSM
1 stop7h 20m
Southwest
Deal found 6/8![Southwest logo]()
$318
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:25 pm
DSM
- SAT
2 stops9h 00m
Southwest
Mon 8/105:00 am
SAT
- DSM
1 stop6h 25m
Southwest
Deal found 6/8![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:15 pm
DSM
- SAT
1 stop7h 53m
United Airlines
Wed 11/185:30 am
SAT
- DSM
2 stops8h 41m
United Airlines
Deal found 6/8![United Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:33 pm
DSM
- SAT
1 stop5h 37m
American Airlines
Tue 7/75:01 am
SAT
- DSM
1 stop4h 10m
American Airlines
Deal found 6/4![American Airlines logo]()
$355
Best flights from Des Moines to San AntonioDiscover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from Des Moines to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:50 pm
DSM
- SAT
1 stop6h 10m
Southwest
Mon 10/262:20 pm
SAT
- DSM
1 stop9h 10m
Southwest
Deal found 6/8![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/711:34 am
DSM
- SAT
1 stop5h 21m
United Airlines
Tue 8/119:10 am
SAT
- DSM
1 stop7h 09m
United Airlines
Deal found 6/5![United Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:04 am
DSM
- SAT
1 stop6h 14m
Delta
Tue 10/274:25 pm
SAT
- DSM
1 stop6h 04m
Delta
Deal found 6/3![Delta logo]()
$391
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:10 am
DSM
- SAT
2 stops7h 00m
Southwest
Fri 7/102:10 pm
SAT
- DSM
1 stop8h 15m
Southwest
Deal found 6/5![Southwest logo]()
$392
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:25 am
DSM
- SAT
1 stop4h 55m
Southwest
Tue 7/211:40 pm
SAT
- DSM
1 stop8h 05m
Southwest
Deal found 6/6![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:05 am
DSM
- SAT
1 stop5h 00m
Southwest
Wed 11/181:55 pm
SAT
- DSM
1 stop6h 50m
Southwest
Deal found 6/6![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
DSM
- SAT
2 stops7h 20m
Southwest
Mon 11/161:55 pm
SAT
- DSM
1 stop6h 50m
Southwest
Deal found 6/7![Southwest logo]()
$412
Last-minute flights from Des Moines to San AntonioDiscover last-minute flight deals from Des Moines to San Antonio. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to San Antonio. Data last updated June 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:33 pm
DSM
- SAT
1 stop5h 37m
American Airlines
Tue 7/75:01 am
SAT
- DSM
1 stop4h 10m
American Airlines
Deal found 6/4![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:40 pm
DSM
- SAT
2 stops8h 20m
Southwest
Tue 7/72:40 pm
SAT
- DSM
2 stops8h 10m
Southwest
Deal found 6/4![Southwest logo]()
$402
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/49:14 am
DSM
- SAT
1 stop7h 45m
United Airlines
Fri 7/105:32 pm
SAT
- DSM
1 stop5h 24m
United Airlines
Deal found 6/7![United Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:45 am
DSM
- SAT
2 stops9h 44m
American Airlines
Fri 7/105:01 am
SAT
- DSM
1 stop4h 10m
American Airlines
Deal found 6/7![American Airlines logo]()
$386
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:10 am
DSM
- SAT
2 stops7h 00m
Southwest
Fri 7/102:10 pm
SAT
- DSM
1 stop8h 15m
Southwest
Deal found 6/5![Southwest logo]()
$392
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:24 pm
DSM
- SAT
2 stops7h 18m
United Airlines
Fri 7/105:57 pm
SAT
- DSM
1 stop4h 38m
United Airlines
Deal found 6/5![United Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/234:48 pm
DSM
- SAT
1 stop4h 15m
American Airlines
Thu 7/305:01 am
SAT
- DSM
1 stop4h 10m
American Airlines
Deal found 6/8![American Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:01 pm
DSM
- SAT
1 stop22h 36m
Multiple Airlines
Fri 8/711:30 am
SAT
- DSM
2 stops27h 05m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$406
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:17 pm
DSM
- SAT
1 stop6h 38m
United Airlines
Tue 8/45:40 am
SAT
- DSM
1 stop5h 02m
United Airlines
Deal found 6/8![United Airlines logo]()
$335
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/314:40 pm
DSM
- SAT
1 stop7h 30m
Southwest
Tue 8/43:15 pm
SAT
- DSM
2 stops6h 40m
Southwest
Deal found 6/8![Southwest logo]()
$341
One-way flights from Des Moines to San AntonioSearch for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from Des Moines to San Antonio. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:13 pm
DSM
- SAT
1 stop5h 47m
American Airlines
Deal found 6/8![American Airlines logo]()
$132
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:00 am
DSM
- SAT
2 stops7h 43m
United Airlines
Deal found 6/8![United Airlines logo]()
$137
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:55 am
DSM
- SAT
1 stop4h 54m
Delta
Deal found 6/8![Delta logo]()
$159
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/21:35 pm
DSM
- SAT
2 stops9h 04m
United Airlines
Deal found 6/8![United Airlines logo]()
$177
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:48 pm
DSM
- SAT
1 stop7h 11m
American Airlines
Deal found 6/7![American Airlines logo]()
$178
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:24 pm
DSM
- SAT
2 stops7h 18m
United Airlines
Deal found 6/7![United Airlines logo]()
$183
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:00 am
DSM
- SAT
1 stop5h 52m
United Airlines
Deal found 6/8![United Airlines logo]()
$199
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:37 pm
DSM
- SAT
1 stop5h 43m
Delta
Deal found 6/8![Delta logo]()
$204
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:50 pm
DSM
- SAT
2 stops7h 05m
Southwest
Deal found 6/6![Southwest logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:56 pm
DSM
- SAT
2 stops12h 16m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:33 pm
DSM
- SAT
1 stop23h 04m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$214
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:40 pm
DSM
- SAT
1 stop4h 15m
American Airlines
Deal found 6/6![American Airlines logo]()
$219
Find flight deals from Des Moines to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $236 (Kiwi.com) |
One-way from | $178 (American Airlines) |
Popular in | March |
Cheapest in | August |
Average price | $537 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Des Moines to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Thu 10/22
1:50 pm-8:00 pm
1 stop6h 10m
San Antonio
Mon 10/26
2:20 pm-11:30 pm
1 stop9h 10m
$323
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Fri 8/7
11:34 am-4:55 pm
1 stop5h 21m
San Antonio
Tue 8/11
9:10 am-4:19 pm
1 stop7h 09m
$381
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Thu 10/22
11:04 am-5:18 pm
1 stop6h 14m
San Antonio
Tue 10/27
4:25 pm-10:29 pm
1 stop6h 04m
$391
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Sat 7/4
6:10 am-1:10 pm
2 stops7h 00m
San Antonio
Fri 7/10
2:10 pm-10:25 pm
1 stop8h 15m
$392
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Tue 7/7
6:25 am-11:20 am
1 stop4h 55m
San Antonio
Tue 7/21
1:40 pm-9:45 pm
1 stop8h 05m
$407
Quickest round-trip
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Tue 11/10
7:05 am-12:05 pm
1 stop5h 00m
San Antonio
Wed 11/18
1:55 pm-8:45 pm
1 stop6h 50m
$407
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Wed 11/11
6:00 am-1:20 pm
2 stops7h 20m
San Antonio
Mon 11/16
1:55 pm-8:45 pm
1 stop6h 50m
$412
Cheapest one-way
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Wed 9/2
6:55 am-11:49 am
1 stop4h 54m
$132
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Tue 6/30
4:48 pm-11:59 pm
1 stop7h 11m
$178
Des MoinesSan Antonio
DSM - SAT
DSMSAT
Des Moines
Tue 6/30
3:24 pm-10:42 pm
2 stops7h 18m
$183
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Des Moines to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Antonio in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Des Moines with our price prediction graph.
DSM-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to San Antonio
How far ahead should I book a flight from Des Moines to San Antonio?
The price you pay for your flight from Des Moines to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to San Antonio?
Currently, July is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $299). Flying from Des Moines to San Antonio in June is currently the most expensive (average of $760). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to San Antonio?
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated June 8, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to San Antonio. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
7.9
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Overall
7.9
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Overall
7.9
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Overall
7.9
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Overall
7.9
Food
7.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
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Top 4 airlines flying from Des Moines to San Antonio
Discover the top 4 airlines that operate flights from Des Moines to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$213 | Average$406 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$262 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$431 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$359 | Average$421 | FlexibilityNo cancel fee | On-time63% |