$349+ Cheap flights from Des Moines (DSM) to Istanbul
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IST
Jul 9 — Jul 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Istanbul with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Istanbul
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to IstanbulExplore the most affordable flight options available from Des Moines to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from Des Moines to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:59 am
DSM
- IST
2 stops32h 31m
Delta
Wed 8/195:20 pm
IST
- DSM
2 stops32h 30m
Delta
Deal found 6/7![Delta logo]()
$638
This Billigflug deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:32 pm
DSM
- IST
2 stops23h 48m
Multiple Airlines
Wed 7/225:20 pm
IST
- DSM
2 stops31h 52m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$670
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/122:45 pm
DSM
- IST
2 stops28h 45m
Delta
Thu 7/234:25 am
IST
- DSM
2 stops24h 24m
Delta
Deal found 6/8![Delta logo]()
$683
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:52 pm
DSM
- IST
2 stops25h 38m
Delta
Mon 7/274:25 am
IST
- DSM
2 stops24h 24m
Delta
Deal found 6/5![Delta logo]()
$753
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:41 pm
DSM
- IST
2 stops28h 49m
Delta
Tue 9/294:25 am
IST
- DSM
2 stops26h 04m
Delta
Deal found 6/8![Delta logo]()
$808
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/33:24 pm
DSM
- IST
2 stops22h 01m
United Airlines
Wed 8/191:55 pm
IST
- DSM
2 stops56h 19m
United Airlines
Deal found 6/5![United Airlines logo]()
$872
This United deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:50 pm
DSM
- IST
2 stops18h 35m
Multiple Airlines
Wed 8/191:55 pm
IST
- DSM
3 stops56h 21m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$878
This Justfly.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:45 pm
DSM
- IST
2 stops23h 20m
Lufthansa
Sat 12/196:30 am
IST
- DSM
2 stops25h 31m
Lufthansa
Deal found 6/4![Lufthansa logo]()
$924
This United deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am
DSM
- IST
3 stops29h 45m
Multiple Airlines
Sat 12/196:30 am
IST
- DSM
2 stops23h 47m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$946
This Bravofly deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:50 pm
DSM
- IST
2 stops23h 15m
Lufthansa
Tue 7/285:40 am
IST
- DSM
2 stops23h 42m
Lufthansa
Deal found 6/8![Lufthansa logo]()
$955
Best flights from Des Moines to IstanbulDiscover carefully curated flight deals from Des Moines to Istanbul that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from Des Moines to Istanbul that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:59 am
DSM
- IST
2 stops32h 31m
Delta
Wed 8/195:20 pm
IST
- DSM
2 stops32h 30m
Delta
Deal found 6/7![Delta logo]()
$638
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/33:24 pm
DSM
- IST
2 stops22h 01m
United Airlines
Wed 8/191:55 pm
IST
- DSM
2 stops56h 19m
United Airlines
Deal found 6/5![United Airlines logo]()
$872
This United deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:50 pm
DSM
- IST
2 stops18h 35m
Multiple Airlines
Wed 8/191:55 pm
IST
- DSM
3 stops56h 21m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$878
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:52 pm
DSM
- IST
2 stops25h 38m
Delta
Thu 7/234:25 am
IST
- DSM
2 stops24h 24m
Delta
Deal found 6/9![Delta logo]()
$683
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:52 pm
DSM
- IST
2 stops25h 38m
Delta
Mon 7/274:25 am
IST
- DSM
2 stops24h 24m
Delta
Deal found 6/5![Delta logo]()
$753
This United deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am
DSM
- IST
3 stops29h 45m
Multiple Airlines
Sat 12/196:30 am
IST
- DSM
2 stops23h 47m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$946
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:23 am
DSM
- IST
2 stops17h 37m
United Airlines
Tue 7/281:55 pm
IST
- DSM
2 stops17h 01m
United Airlines
Deal found 6/6![United Airlines logo]()
$1,009
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/212:45 pm
DSM
- IST
2 stops28h 45m
Delta
Tue 7/284:25 am
IST
- DSM
2 stops24h 24m
Delta
Deal found 6/7![Delta logo]()
$1,018
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:52 pm
DSM
- IST
2 stops25h 38m
Delta
Sun 7/265:20 pm
IST
- DSM
2 stops31h 32m
Delta
Deal found 6/4![Delta logo]()
$1,059
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:45 pm
DSM
- IST
2 stops28h 45m
Delta
Thu 7/304:25 am
IST
- DSM
2 stops24h 24m
Delta
Deal found 6/8![Delta logo]()
$1,078
Last-minute flights from Des Moines to IstanbulDiscover last-minute flight deals from Des Moines to Istanbul. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Istanbul. Data last updated June 9, 2026 and is based on user searches.
This Billigflug deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:32 pm
DSM
- IST
2 stops23h 48m
Multiple Airlines
Wed 7/225:20 pm
IST
- DSM
2 stops31h 52m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$670
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/122:45 pm
DSM
- IST
2 stops28h 45m
Delta
Thu 7/234:25 am
IST
- DSM
2 stops24h 24m
Delta
Deal found 6/8![Delta logo]()
$683
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:52 pm
DSM
- IST
2 stops25h 38m
Delta
Sat 7/255:20 pm
IST
- DSM
2 stops31h 32m
Delta
Deal found 6/8![Delta logo]()
$1,053
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:52 pm
DSM
- IST
2 stops25h 38m
Delta
Sun 7/265:20 pm
IST
- DSM
2 stops31h 32m
Delta
Deal found 6/4![Delta logo]()
$1,059
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:52 pm
DSM
- IST
2 stops25h 38m
Delta
Mon 7/274:25 am
IST
- DSM
2 stops24h 24m
Delta
Deal found 6/5![Delta logo]()
$753
This Bravofly deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:50 pm
DSM
- IST
2 stops23h 15m
Lufthansa
Tue 7/285:40 am
IST
- DSM
2 stops23h 42m
Lufthansa
Deal found 6/8![Lufthansa logo]()
$955
This Flysmarter deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:23 am
DSM
- IST
3 stops21h 32m
Multiple Airlines
Tue 7/281:55 pm
IST
- DSM
2 stops17h 01m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$989
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:23 am
DSM
- IST
2 stops17h 37m
United Airlines
Tue 7/281:55 pm
IST
- DSM
2 stops17h 01m
United Airlines
Deal found 6/6![United Airlines logo]()
$1,009
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/212:45 pm
DSM
- IST
2 stops28h 45m
Delta
Tue 7/284:25 am
IST
- DSM
2 stops24h 24m
Delta
Deal found 6/7![Delta logo]()
$1,018
One-way flights from Des Moines to IstanbulSearch for one-way flight options from Des Moines to Istanbul. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from Des Moines to Istanbul. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:45 pm
DSM
- IST
2 stops28h 45m
Delta
Deal found 6/8![Delta logo]()
$349
This Lufthansa deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:23 am
DSM
- IST
2 stops26h 02m
Lufthansa
Deal found 6/9![Lufthansa logo]()
$544
This Air Canada deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:00 am
DSM
- IST
3 stops21h 00m
Air Canada
Deal found 6/8![Air Canada logo]()
$691
This Air Canada deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:00 am
DSM
- IST
3 stops21h 00m
Air Canada
Deal found 6/9![Air Canada logo]()
$850
This Qatar Airways deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:35 pm
DSM
- IST
2 stops38h 20m
Qatar Airways
Deal found 6/8![Qatar Airways logo]()
$4,908
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:48 pm
DSM
- IST
2 stops23h 37m
American Airlines
Deal found 6/7![American Airlines logo]()
$6,995
Find flight deals from Des Moines to Istanbul
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Istanbul (TR5). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.
Round-trip from | $638 (Delta) |
|---|---|
One-way from | $349 (Delta) |
Popular in | July |
Cheapest in | March |
Average price | $1,446 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Des Moines to Istanbul that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Mon 8/3
10:59 am-3:30 am
2 stops32h 31m
Istanbul
Wed 8/19
5:20 pm-5:50 pm
2 stops32h 30m
$638
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Sun 7/12
5:52 pm-3:30 am
2 stops25h 38m
Istanbul
Thu 7/23
4:25 am-8:49 pm
2 stops24h 24m
$683
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Mon 7/20
5:52 pm-3:30 am
2 stops25h 38m
Istanbul
Mon 7/27
4:25 am-8:49 pm
2 stops24h 24m
$753
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Mon 8/3
3:24 pm-9:25 pm
2 stops22h 01m
Istanbul
Wed 8/19
1:55 pm-2:14 pm
2 stops56h 19m
$872
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Mon 8/3
6:50 pm-9:25 pm
2 stops18h 35m
Istanbul
Wed 8/19
1:55 pm-2:16 pm
3 stops56h 21m
$878
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Fri 12/4
8:00 am-10:45 pm
3 stops29h 45m
Istanbul
Sat 12/19
6:30 am-9:17 pm
2 stops23h 47m
$946
Quickest round-trip
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Tue 7/21
11:23 am-1:00 pm
2 stops17h 37m
Istanbul
Tue 7/28
1:55 pm-10:56 pm
2 stops17h 01m
$1,009
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Tue 7/21
2:45 pm-3:30 am
2 stops28h 45m
Istanbul
Tue 7/28
4:25 am-8:49 pm
2 stops24h 24m
$1,018
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Sun 7/19
5:52 pm-3:30 am
2 stops25h 38m
Istanbul
Sun 7/26
5:20 pm-4:52 pm
2 stops31h 32m
$1,059
Des MoinesIstanbul
DSM - IST
DSMIST
Des Moines
Thu 7/23
2:45 pm-3:30 am
2 stops28h 45m
Istanbul
Thu 7/30
4:25 am-8:49 pm
2 stops24h 24m
$1,078
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Istanbul
Have a flexible travel schedule? Discover the best time to fly to Istanbul from Des Moines with our price prediction graph.
DSM-TR5
DSM-IST
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Istanbul
DSM-TR5
DSM-IST
How much does it cost to fly round-trip from Des Moines to Istanbul?
Reviews of airlines servicing Istanbul
Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated June 9, 2026.
Get a feel of what it's like to fly with Delta and United Airlines from Des Moines to Istanbul by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Complete your trip
Flights by cabin class
Other flight options
Other flights from Des Moines
Popular flights
Complete your trip
Complete your trip to Istanbul by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Istanbul by cabin class
Find flights from Des Moines to Istanbul, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Istanbul flights
Browse other Des Moines and Istanbul flight options. Last updated on June 9, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on June 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Istanbul
Discover the top 2 airlines that operate flights from Des Moines to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$572 | Average$807 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$638 | Average$1,181 | FlexibilityNo cancel fee | On-timeN/A |