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Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Jackson, Mississippi to Sicily as you normally would.
Related info for your journey
Useful info, stats and facts about Jackson to Sicily flights.
For a flight from Jackson to Sicily, you will be flying from Jackson-Evers Intl. Jackson-Evers Intl (JAN) is just 6.3 mi from the center of the city.
This is defined as Jackson-Evers Intl Airport (JAN) and Catania Fontanarossa Airport (CTA). Codes like Catania Fontanarossa Airport are often used to just call airports uniquely. Palermo Punta Raisi Airport (PMO), Trapani Birgi Airport (TPS), Lampedusa Airport (LMP), Comiso Airport (CIY), Pantelleria Airport (PNL) are other airports near this flight route and their unique identifiers/IATA codes.