To save up to 13% on this flight, we recommend booking at least 21 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from San Francisco to Sanford from $197 1-2 weeks out and tickets from $229 for flights departing within the next 72 hours.
Due to multiple factors, expect to potentially pay more when booking in December. For low rates, August can be a great choice for travel to Sanford. Flights to Sanford from San Francisco in August are about $202 on average during August, but can be found for as low as $76.