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$499+ Cheap flights from Knoxville (TYS) to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PRG
Dec 10 — Dec 171
Wed 12/10
Wed 12/17
1 adult, Economy
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Find flight deals from Knoxville to Prague

Cheapest flights from Knoxville to Prague
Explore the most affordable flight options available from Knoxville to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:25 pmTYS - PRG
2 stops21h 00mUnited Airlines
Mon 12/153:10 pmPRG - TYS
2 stops25h 03mUnited Airlines
Deal found 11/8$505
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:45 amTYS - PRG
2 stops34h 40mUnited Airlines
Fri 1/93:15 pmPRG - TYS
2 stops49h 17mUnited Airlines
Deal found 11/10$841
This Brussels Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/82:30 pmTYS - PRG
3 stops25h 40mBrussels Airlines
Mon 12/156:50 amPRG - TYS
2 stops18h 39mBrussels Airlines
Deal found 11/8$847
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:45 amTYS - PRG
2 stops30h 10mUnited Airlines
Wed 12/313:10 pmPRG - TYS
2 stops31h 50mUnited Airlines
Deal found 11/9$868
This Brussels Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/152:30 pmTYS - PRG
3 stops25h 40mBrussels Airlines
Sat 12/276:50 amPRG - TYS
3 stops43h 01mBrussels Airlines
Deal found 11/9$1,408
This Gotogate deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/152:30 pmTYS - PRG
2 stops19h 35mLufthansa
Sat 12/274:45 pmPRG - TYS
2 stops37h 14mLufthansa
Deal found 11/9$1,471
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:45 amTYS - PRG
2 stops25h 55mUnited Airlines
Thu 1/11:45 pmPRG - TYS
2 stops14h 54mUnited Airlines
Deal found 11/10$2,032
This Air Canada deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:00 pmTYS - PRG
3 stops17h 55mAir Canada
Fri 1/97:35 amPRG - TYS
3 stops17h 52mAir Canada
Deal found 11/10$2,079
This Brussels Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:00 pmTYS - PRG
3 stops46h 05mBrussels Airlines
Fri 1/96:50 amPRG - TYS
2 stops18h 37mBrussels Airlines
Deal found 11/10$2,909
This Arangrant deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arangrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:52 pmTYS - PRG
2 stops16h 13mLufthansa
Sun 11/167:25 amPRG - TYS
2 stops18h 55mLufthansa
Deal found 11/9$9,649

Cheap flight deals from Knoxville to Prague

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Prague (PRG). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$500
(Cheapflightsfares)

One-way from

$499
(American Airlines)

Popular in

November

Cheapest in

January

Average price

$1,567
Provider with most accurate pricing for Knoxville McGhee Tyson-Václav Havel Prague flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Václav Havel Prague flights.
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From Knoxville McGhee Tyson to Václav Havel Prague
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One-way flight from Knoxville McGhee Tyson to Václav Havel Prague
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($55 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Knoxville to Prague that are best for you.

Fly from

Knoxville

Fly to

Prague

Route

Depart

Return

Price

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Sat 1/31

1:59 pm-10:25 pm

2 stops26h 26m

Václav Havel Prague

Sat 2/7

10:30 am-7:27 pm

2 stops14h 57m

$500

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Mon 12/8

7:25 pm-10:25 pm

2 stops21h 00m

Václav Havel Prague

Mon 12/15

3:10 pm-10:13 am

2 stops25h 03m

$505

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Sun 2/8

6:45 am-10:25 pm

2 stops33h 40m

Václav Havel Prague

Sat 2/14

1:45 pm-3:15 pm

2 stops55h 30m

$519

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Fri 2/27

4:06 pm-9:45 am

2 stops35h 39m

Václav Havel Prague

Sun 3/8

8:50 pm-11:44 pm

2 stops31h 54m

$570

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Sat 1/31

2:25 pm-1:55 pm

3 stops17h 30m

Václav Havel Prague

Sat 2/7

7:35 am-7:27 pm

3 stops17h 52m

$720

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Sat 1/31

2:25 pm-10:10 pm

3 stops25h 45m

Václav Havel Prague

Sat 2/7

6:50 am-7:27 pm

2 stops18h 37m

$747

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Sun 2/8

2:25 pm-10:10 pm

3 stops25h 45m

Václav Havel Prague

Sat 2/14

11:40 am-7:29 pm

2 stops37h 49m

$760

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Thu 4/16

10:50 am-4:05 pm

2 stops23h 15m

Václav Havel Prague

Tue 4/21

6:00 am-7:31 pm

2 stops19h 31m

$805

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Fri 12/26

5:45 am-10:25 pm

2 stops34h 40m

Václav Havel Prague

Fri 1/9

3:15 pm-10:32 am

2 stops49h 17m

$841

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Mon 12/8

2:30 pm-10:10 pm

3 stops25h 40m

Václav Havel Prague

Mon 12/15

6:50 am-7:29 pm

2 stops18h 39m

$847

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 15 results
1
2

Compare providers for flights from Knoxville to Prague

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Prague in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Prague flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Prague flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Prague flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Prague flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Prague flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Prague

What is the cheapest month to book a flight from Knoxville to Prague?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Prague (average of $626). Flying from Knoxville to Prague in June is currently the most expensive (average of $1,441). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to PRG?

Find hourly flight availability from Knoxville to Prague. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 10, 2025.

It’s typically best to fly out from Knoxville to Prague in the morning. Doing so could potentially save you 11% on the flight price compared to flying at noon, which is usually more expensive.

How much does it cost to fly round-trip from Knoxville to Prague?

Reviews of airlines servicing Prague

Get insights into the airlines that provide service to Prague. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Prague. Reviews last updated November 10, 2025.
Read through reviews of airlines operating flights from Knoxville to Prague, such as Delta, United Airlines, and Lufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,003 reviews

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,003 reviews
Delta
7.9
Good
8,003 reviews

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,012 reviews
Delta
7.9
Good
8,003 reviews

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,564 reviews
Delta
7.9
Good
8,003 reviews

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Prague?

    Departing from Knoxville to Prague will take you 21h. The distance from Knoxville to Prague is about 4697 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Prague round-trip?

    Flying on Lufthansa is currently your cheapest option to Prague, with prices starting at $634. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $650 and $666, respectively. Lufthansa is priced at 34% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Knoxville to Prague one-way?

    One-way options have recently been found by users for as low as $499 on American Airlines. Other airlines that offer cheap prices include Air Canada from $608 and British Airways from $947 one-way.

  • Can I find deals for flights from Knoxville to Prague that include hotel bookings?

    Yes. In addition to deals on Knoxville to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Prague.

  • Can I find deals for business class flights from Knoxville to Prague?

    Yes. Cheapflights offers flight deals from Knoxville to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Prague?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Prague (average of $626). Flying from Knoxville to Prague in June is currently the most expensive (average of $1,441). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Prague

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Prague flights
Blountville to Prague flights
Chattanooga to Prague flights
Memphis to Prague flights

Top 3 airlines flying from Knoxville to Prague

Discover the top 3 airlines that operate flights from Knoxville to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$634Average$1,136FlexibilityNo cancel feeOn-time76%
DeltaCheapest$650Average$909FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$666Average$948FlexibilityNo cancel feeOn-time69%

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