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It’s generally more expensive to depart on a Wednesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santa Fe to León, Guanajuato as you normally would.
Related info for your journey
Useful info, stats and facts about Santa Fe to León flights.
Santa Fe Airport is SAF and León Del Bajio Airport is BJX. These codes are created by the International Air Transport Association (IATA) and airlines use them to identify the departing and arrival airports in the flight routes they service.