To save on the cost of your flight from Mesa to John Wayne/Orange County, book at least 33 days before your planned departure. Booking around this time can save you about 72% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $375 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $533.
August can be a great time to fly to John Wayne/Orange County from Mesa with a flight ticket averaging about $307. Cheapflights users have found deals in the month of August for as cheap as $107. The most expensive prices can be found in the month of December.