To save up to 43% on this flight, we recommend booking at least 57 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Islip, New York to Italy from $619 1-2 weeks out and tickets from $731 for flights departing within the next 72 hours.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Islip, New York to Italy as you normally would.