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$344+ Cheap flights from Santa Fe to Indianapolis (SAF - IND)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — IND
Sep 1 — Sep 81
Tue 9/1
Tue 9/8
1 adult, Economy
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Cheap flight deals from Santa Fe to Indianapolis

Cheapest flights from Santa Fe to Indianapolis
Explore the most affordable flight options available from Santa Fe to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:08 pm
SAF
-
IND
1 stop7h 35m
American Airlines
Tue 9/86:04 am
IND
-
SAF
1 stop5h 37m
American Airlines
Deal found 7/30$344
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:10 am
SAF
-
IND
1 stop8h 07m
American Airlines
Mon 8/173:56 pm
IND
-
SAF
1 stop7h 33m
American Airlines
Deal found 7/29$374
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:21 pm
SAF
-
IND
1 stop4h 51m
United Airlines
Wed 9/96:00 am
IND
-
SAF
2 stops8h 37m
United Airlines
Deal found 7/31$402
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:21 pm
SAF
-
IND
1 stop4h 51m
United Airlines
Sat 8/298:00 am
IND
-
SAF
1 stop6h 47m
United Airlines
Deal found 8/1$414
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:05 am
SAF
-
IND
2 stops11h 10m
American Airlines
Mon 9/216:00 am
IND
-
SAF
1 stop5h 43m
American Airlines
Deal found 7/30$465
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:58 pm
SAF
-
IND
1 stop7h 25m
American Airlines
Sun 8/26:01 am
IND
-
SAF
1 stop5h 40m
American Airlines
Deal found 7/28$484
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:22 pm
SAF
-
IND
2 stops8h 34m
United Airlines
Mon 8/178:00 am
IND
-
SAF
1 stop6h 47m
United Airlines
Deal found 7/29$490
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:22 pm
SAF
-
IND
1 stop6h 50m
United Airlines
Tue 9/86:53 am
IND
-
SAF
2 stops12h 03m
United Airlines
Deal found 8/2$548
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:30 am
SAF
-
IND
2 stops11h 26m
United Airlines
Wed 9/99:00 am
IND
-
SAF
2 stops13h 28m
United Airlines
Deal found 7/31$553

Find flight deals from Santa Fe to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$344
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$578
Provider with most accurate pricing for Santa Fe-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Fe-Indianapolis flights.
Search Deals
From Santa Fe to Indianapolis
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($80 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
Use the filters below to find and compare flights from Santa Fe to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Thu 9/3

3:21 pm-10:12 pm

1 stop4h 51m

Indianapolis

Wed 9/9

6:00 am-12:37 pm

2 stops8h 37m

$402

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Fri 9/4

3:21 pm-10:12 pm

1 stop4h 51m

Indianapolis

Wed 9/9

6:00 am-12:37 pm

2 stops8h 37m

$424
Quickest round-trip

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Tue 8/25

3:21 pm-10:12 pm

1 stop4h 51m

Indianapolis

Sat 8/29

7:00 am-12:47 pm

2 stops7h 47m

$424

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Wed 9/16

6:05 am-7:15 pm

2 stops11h 10m

Indianapolis

Mon 9/21

6:00 am-9:43 am

1 stop5h 43m

$465

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Thu 8/13

1:22 pm-11:56 pm

2 stops8h 34m

Indianapolis

Mon 8/17

8:00 am-12:47 pm

1 stop6h 47m

$490

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Fri 9/4

1:22 pm-10:12 pm

1 stop6h 50m

Indianapolis

Tue 9/8

6:53 am-4:56 pm

2 stops12h 03m

$548

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Thu 9/3

7:10 am-2:41 pm

1 stop5h 31m

Indianapolis

Tue 9/8

6:53 am-4:56 pm

2 stops12h 03m

$604

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Santa Fe-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Fe-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Fe-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Fe-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Fe-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Fe to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated August 2, 2026.
Get a feel of what it's like to fly with American Airlines from Santa Fe to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,845 reviews

Entertainment

6.8

Comfort

7.2

Boarding

7.5

Crew

7.9

Food

6.4

Overall

7.1

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go
American Airlines
7.1
Good
11,845 reviews
American Airlines
7.1
Good
11,845 reviews

Entertainment

6.8

Comfort

7.2

Boarding

7.5

Crew

7.9

Food

6.4

Overall

7.1

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to Indianapolis?

    Departing from Santa Fe to Indianapolis will take you 4h 51m. The distance between Santa Fe and Indianapolis is about 1116 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Santa Fe to Indianapolis round-trip?

    Currently priced at $254, American Airlines will fly you from Santa Fe to Indianapolis and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is priced at 48% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Santa Fe to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Indianapolis.

  • Can I find deals for business class flights from Santa Fe to Indianapolis?

    Yes. Cheapflights offers flight deals from Santa Fe to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Kokomo
Fishers
Westfield
Franklin
Mooresville
Plainfield
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
Speedway

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Santa Fe to Indianapolis

Discover the top airline that operate flights from Santa Fe to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$254Average$444FlexibilityNo cancel feeOn-time71%

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