To save up to 26% on this flight, we recommend booking at least 44 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Sanford to Houston from $118 1-2 weeks out and tickets from $157 for flights departing within the next 72 hours.
Flights from Sanford to Houston lean towards being more expensive in December. Prices are generally better when you fly from Sanford to Houston in February, with the cheapest ticket starting at $68.