$95+ Cheap flights from Iowa to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SFO
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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Cheapest flights from Iowa to San FranciscoExplore the most affordable flight options available from Iowa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from Iowa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:15 pm
OMA
- SFO
1 stop6h 08m
Frontier
Wed 7/296:00 am
SFO
- OMA
1 stop11h 15m
Frontier
Deal found 6/4![Frontier logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:00 pm
OMA
- SFO
1 stop6h 23m
Frontier
Wed 7/296:00 am
SFO
- OMA
1 stop11h 15m
Frontier
Deal found 6/4![Frontier logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:38 pm
DSM
- SFO
1 stop25h 18m
Multiple Airlines
Tue 9/15:11 pm
SFO
- DSM
2 stops18h 20m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:15 pm
OMA
- SFO
1 stop17h 12m
Frontier
Tue 7/286:00 am
SFO
- OMA
1 stop11h 15m
Frontier
Deal found 6/4![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- SFO
1 stop19h 24m
Multiple Airlines
Tue 7/214:30 pm
SFO
- DSM
1 stop18h 29m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$236
This Super.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:00 pm
OMA
- SFO
1 stop6h 23m
Frontier
Sun 7/269:39 pm
SFO
- OMA
1 stop19h 36m
Frontier
Deal found 6/4![Frontier logo]()
$238
This Frontier deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:00 pm
OMA
- SFO
1 stop6h 23m
Frontier
Sun 7/126:00 am
SFO
- OMA
1 stop11h 15m
Frontier
Deal found 6/8![Frontier logo]()
$239
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:15 pm
OMA
- SFO
1 stop5h 30m
Southwest
Wed 10/141:20 pm
SFO
- OMA
1 stop5h 50m
Southwest
Deal found 6/8![Southwest logo]()
$242
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:15 pm
OMA
- SFO
1 stop6h 12m
Frontier
Sat 7/46:00 am
SFO
- OMA
1 stop11h 30m
Frontier
Deal found 6/6![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:06 pm
OMA
- SFO
1 stop13h 40m
Multiple Airlines
Mon 8/249:35 pm
SFO
- OMA
1 stop19h 59m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$246
This Super.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
OMA
- SFO
1 stop6h 23m
Frontier
Sat 7/119:39 pm
SFO
- OMA
1 stop19h 36m
Frontier
Deal found 6/6![Frontier logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:13 pm
DSM
- SFO
1 stop20h 28m
Multiple Airlines
Tue 7/214:30 pm
SFO
- DSM
1 stop18h 29m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$273
Best flights from Iowa to San FranciscoDiscover carefully curated flight deals from Iowa to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from Iowa to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:15 pm
OMA
- SFO
1 stop5h 30m
Southwest
Wed 10/1410:20 am
SFO
- OMA
2 stops8h 25m
Southwest
Deal found 6/8![Southwest logo]()
$247
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:38 am
OMA
- SFO
Nonstop3h 50m
United Airlines
Tue 7/74:10 pm
SFO
- OMA
Nonstop3h 34m
United Airlines
Deal found 6/5![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:09 pm
MLI
- SFO
1 stop8h 49m
Delta
Wed 9/910:30 pm
SFO
- MLI
1 stop9h 56m
Delta
Deal found 6/8![Delta logo]()
$331
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:06 am
ALO
- SFO
2 stops13h 37m
American Airlines
Fri 7/106:04 am
SFO
- ALO
1 stop16h 25m
American Airlines
Deal found 6/8![American Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:38 am
OMA
- SFO
Nonstop3h 50m
United Airlines
Sun 7/56:45 pm
SFO
- OMA
Nonstop3h 34m
United Airlines
Deal found 6/8![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:09 pm
MLI
- SFO
1 stop8h 49m
Delta
Mon 8/1710:00 pm
SFO
- MLI
1 stop10h 25m
Delta
Deal found 6/8![Delta logo]()
$345
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/233:35 pm
OMA
- SFO
Nonstop3h 44m
United Airlines
Mon 8/3111:30 pm
SFO
- OMA
1 stop8h 52m
United Airlines
Deal found 6/8![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:15 am
DSM
- SFO
1 stop5h 35m
Southwest
Sun 9/69:10 am
SFO
- DSM
2 stops10h 05m
Southwest
Deal found 6/8![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:55 am
MLI
- SFO
1 stop9h 47m
Delta
Mon 11/210:30 pm
SFO
- MLI
1 stop9h 56m
Delta
Deal found 6/6![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am
OMA
- SFO
1 stop5h 21m
United Airlines
Mon 9/288:10 am
SFO
- OMA
Nonstop3h 23m
United Airlines
Deal found 6/7![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:05 pm
DSM
- SFO
1 stop7h 30m
Southwest
Mon 8/316:20 am
SFO
- DSM
1 stop5h 25m
Southwest
Deal found 6/8![Southwest logo]()
$363
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:19 pm
CID
- SFO
1 stop6h 55m
Delta
Thu 9/243:16 pm
SFO
- CID
1 stop5h 33m
Delta
Deal found 6/8![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:55 am
DSM
- SFO
2 stops9h 10m
Southwest
Tue 10/1311:40 pm
SFO
- DSM
1 stop9h 45m
Southwest
Deal found 6/8![Southwest logo]()
$395
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:38 am
OMA
- SFO
Nonstop3h 50m
United Airlines
Sun 8/95:00 am
SFO
- OMA
1 stop5h 42m
United Airlines
Deal found 6/6![United Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:05 pm
MLI
- SFO
1 stop9h 31m
Delta
Tue 7/1411:59 pm
SFO
- MLI
1 stop8h 13m
Delta
Deal found 6/4![Delta logo]()
$373
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/223:45 pm
DSM
- SFO
2 stops9h 45m
Southwest
Wed 7/295:30 am
SFO
- DSM
1 stop7h 35m
Southwest
Deal found 6/9![Southwest logo]()
$400
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:10 pm
MLI
- SFO
1 stop8h 47m
Delta
Sun 9/276:00 am
SFO
- MLI
1 stop8h 22m
Delta
Deal found 6/6![Delta logo]()
$382
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:46 pm
CID
- SFO
1 stop7h 44m
United Airlines
Sun 10/45:00 am
SFO
- CID
1 stop6h 07m
United Airlines
Deal found 6/5![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:49 pm
LSE
- SFO
1 stop7h 03m
American Airlines
Fri 7/102:36 pm
SFO
- LSE
1 stop7h 23m
American Airlines
Deal found 6/5![American Airlines logo]()
$575
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:15 am
OMA
- SFO
2 stops7h 45m
Southwest
Sat 7/115:00 am
SFO
- OMA
1 stop5h 25m
Southwest
Deal found 6/6![Southwest logo]()
$404
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:05 pm
MLI
- SFO
1 stop7h 44m
Delta
Mon 8/310:10 pm
SFO
- MLI
1 stop10h 15m
Delta
Deal found 6/5![Delta logo]()
$382
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:38 am
OMA
- SFO
Nonstop3h 50m
United Airlines
Mon 8/36:45 pm
SFO
- OMA
Nonstop3h 34m
United Airlines
Deal found 6/8![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:10 pm
DSM
- SFO
2 stops9h 25m
Southwest
Thu 9/179:55 am
SFO
- DSM
2 stops9h 20m
Southwest
Deal found 6/7![Southwest logo]()
$425
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:18 am
LSE
- SFO
1 stop7h 03m
American Airlines
Fri 10/1611:56 pm
SFO
- LSE
1 stop7h 27m
American Airlines
Deal found 6/5![American Airlines logo]()
$624
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:16 pm
CID
- SFO
1 stop6h 46m
Delta
Mon 8/176:13 am
SFO
- CID
1 stop7h 22m
Delta
Deal found 6/8![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:00 pm
OMA
- SFO
1 stop5h 55m
United Airlines
Tue 10/208:10 am
SFO
- OMA
Nonstop3h 23m
United Airlines
Deal found 6/5![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:00 pm
ALO
- SFO
1 stop20h 19m
American Airlines
Sat 6/2711:10 pm
SFO
- ALO
1 stop13h 13m
American Airlines
Deal found 6/6![American Airlines logo]()
$632
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:10 pm
DSM
- SFO
2 stops7h 05m
Southwest
Thu 7/92:35 pm
SFO
- DSM
1 stop5h 50m
Southwest
Deal found 6/6![Southwest logo]()
$436
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:09 pm
MLI
- SFO
1 stop8h 49m
Delta
Thu 8/2710:00 pm
SFO
- MLI
1 stop10h 25m
Delta
Deal found 6/9![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
OMA
- SFO
1 stop7h 25m
United Airlines
Fri 7/316:45 pm
SFO
- OMA
Nonstop3h 34m
United Airlines
Deal found 6/4![United Airlines logo]()
$409
Last-minute flights from Iowa to San FranciscoDiscover last-minute flight deals from Iowa to San Francisco. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to San Francisco. Data last updated June 9, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:15 pm
OMA
- SFO
1 stop6h 12m
Frontier
Sat 7/46:00 am
SFO
- OMA
1 stop11h 30m
Frontier
Deal found 6/6![Frontier logo]()
$245
This Super.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:15 pm
OMA
- SFO
1 stop6h 12m
Frontier
Fri 7/39:43 pm
SFO
- OMA
1 stop19h 47m
Frontier
Deal found 6/8![Frontier logo]()
$248
This Super.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
OMA
- SFO
1 stop6h 23m
Frontier
Sat 7/119:39 pm
SFO
- OMA
1 stop19h 36m
Frontier
Deal found 6/6![Frontier logo]()
$247
This Frontier deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:00 pm
OMA
- SFO
1 stop6h 23m
Frontier
Sun 7/126:00 am
SFO
- OMA
1 stop11h 15m
Frontier
Deal found 6/8![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:13 pm
DSM
- SFO
1 stop20h 28m
Multiple Airlines
Tue 7/214:30 pm
SFO
- DSM
1 stop18h 29m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- SFO
1 stop19h 24m
Multiple Airlines
Tue 7/214:30 pm
SFO
- DSM
1 stop18h 29m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- SFO
1 stop19h 24m
Multiple Airlines
Mon 7/2010:23 pm
SFO
- DSM
2 stops36h 36m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:15 pm
OMA
- SFO
1 stop6h 08m
Frontier
Wed 7/296:00 am
SFO
- OMA
1 stop11h 15m
Frontier
Deal found 6/4![Frontier logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:15 pm
OMA
- SFO
1 stop17h 12m
Frontier
Tue 7/286:00 am
SFO
- OMA
1 stop11h 15m
Frontier
Deal found 6/4![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:15 pm
OMA
- SFO
1 stop6h 08m
Frontier
Mon 7/279:39 pm
SFO
- OMA
1 stop19h 36m
Frontier
Deal found 6/4![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:00 pm
OMA
- SFO
1 stop6h 23m
Frontier
Wed 7/296:00 am
SFO
- OMA
1 stop11h 15m
Frontier
Deal found 6/4![Frontier logo]()
$186
This Super.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:00 pm
OMA
- SFO
1 stop6h 23m
Frontier
Sun 7/269:39 pm
SFO
- OMA
1 stop19h 36m
Frontier
Deal found 6/4![Frontier logo]()
$238
One-way flights from Iowa to San FranciscoSearch for one-way flight options from Iowa to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from Iowa to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:15 pm
OMA
- SFO
1 stop6h 08m
Frontier
Deal found 6/4![Frontier logo]()
$95
This Trip.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- SFO
1 stop14h 29m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$119
This Frontier deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:15 pm
OMA
- SFO
1 stop6h 12m
Frontier
Deal found 6/8![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:01 pm
DSM
- SFO
2 stops25h 37m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$121
This Super.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:15 pm
OMA
- SFO
1 stop6h 12m
Frontier
Deal found 6/8![Frontier logo]()
$124
This Priceline deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:15 pm
OMA
- SFO
1 stop6h 12m
Frontier
Deal found 6/8![Frontier logo]()
$125
This Frontier deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/288:15 pm
OMA
- SFO
1 stop6h 12m
Frontier
Deal found 6/4![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:19 pm
DSM
- SFO
2 stops32h 21m
Frontier
Deal found 6/9![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:00 pm
OMA
- SFO
2 stops24h 23m
Frontier
Deal found 6/6![Frontier logo]()
$129
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:15 pm
OMA
- SFO
1 stop5h 05m
Southwest
Deal found 6/8![Southwest logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- SFO
1 stop25h 14m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$130
This Super.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:19 pm
OMA
- SFO
1 stop6h 03m
Frontier
Deal found 6/6![Frontier logo]()
$131
Find flight deals from Iowa to San Francisco
Keep the following information in mind while searching for Iowa to San Francisco flight deals. Data was last updated June 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $183 (Kiwi.com) |
One-way from | $95 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $484 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Iowa to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaSan Francisco
OMA - SFO
OMASFO
Omaha Eppley Airfield
Wed 10/7
6:15 pm-9:45 pm
1 stop5h 30m
San Francisco
Wed 10/14
10:20 am-8:45 pm
2 stops8h 25m
$247
Quickest round-trip
OmahaSan Francisco
OMA - SFO
OMASFO
Omaha Eppley Airfield
Fri 7/3
7:38 am-9:28 am
Nonstop3h 50m
San Francisco
Tue 7/7
4:10 pm-9:44 pm
Nonstop3h 34m
$309
OmahaSan Francisco
OMA - SFO
OMASFO
Omaha Eppley Airfield
Wed 7/1
7:38 am-9:28 am
Nonstop3h 50m
San Francisco
Sun 7/5
6:45 pm-12:19 am
Nonstop3h 34m
$319
OmahaSan Francisco
OMA - SFO
OMASFO
Omaha Eppley Airfield
Sun 8/23
3:35 pm-5:19 pm
Nonstop3h 44m
San Francisco
Mon 8/31
11:30 pm-10:22 am
1 stop8h 52m
$319
OmahaSan Francisco
OMA - SFO
OMASFO
Omaha Eppley Airfield
Sat 9/26
6:00 am-9:21 am
1 stop5h 21m
San Francisco
Mon 9/28
8:10 am-1:33 pm
Nonstop3h 23m
$329
MolineSan Francisco
MLI - SFO
MLISFO
Moline Quad-City
Tue 9/1
5:09 pm-11:58 pm
1 stop8h 49m
San Francisco
Wed 9/9
10:30 pm-10:26 am
1 stop9h 56m
$331
MolineSan Francisco
MLI - SFO
MLISFO
Moline Quad-City
Wed 8/12
5:09 pm-11:58 pm
1 stop8h 49m
San Francisco
Mon 8/17
10:00 pm-10:25 am
1 stop10h 25m
$345
Des MoinesSan Francisco
DSM - SFO
DSMSFO
Des Moines
Wed 9/2
7:15 am-10:50 am
1 stop5h 35m
San Francisco
Sun 9/6
9:10 am-9:15 pm
2 stops10h 05m
$353
MolineSan Francisco
MLI - SFO
MLISFO
Moline Quad-City
Fri 10/30
5:55 am-1:42 pm
1 stop9h 47m
San Francisco
Mon 11/2
10:30 pm-10:26 am
1 stop9h 56m
$359
Cedar RapidsSan Francisco
CID - SFO
CIDSFO
Cedar Rapids
Sat 9/19
12:19 pm-5:14 pm
1 stop6h 55m
San Francisco
Thu 9/24
3:16 pm-10:49 pm
1 stop5h 33m
$359
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Iowa with our price prediction graph.
OMA-SFO
DSM-SFO
MLI-SFO
CID-SFO
LSE-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to San Francisco
USIA-SFO
OMA-SFO
DSM-SFO
MLI-SFO
CID-SFO
What is the cheapest month to book a flight from Iowa to San Francisco?
Currently, February is the cheapest month in which you can book a flight from Iowa to San Francisco (average of $91). Flying from Iowa to San Francisco in January is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to San Francisco?
How far ahead should I book a flight from Iowa to San Francisco?
The price you pay for your flight from Iowa to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 57 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Iowa to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
Cupertino
Emeryville
Newark
Watsonville
San Bruno
San Ramon
Vacaville
Roseville
San Carlos
Redwood City
Daly City
Turlock
Sunnyvale
Vallejo
San Lorenzo
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Iowa to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to San Francisco by cabin class
Find flights from Iowa to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and San Francisco flights
Browse other Iowa and San Francisco flight options. Last updated on June 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 9, 2026.
Iowa to San Francisco flights
Consider these flights traveling from Iowa to San Francisco.
Top 5 airlines flying from Iowa to San Francisco
Discover the top 5 airlines that operate flights from Iowa to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$129 | Average$245 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$263 | Average$375 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$288 | Average$478 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$288 | Average$454 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$336 | Average$486 | FlexibilityNo cancel fee | On-time63% |