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San Diego

$99+ Cheap flights from Mississippi to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
Jul 13 — Jul 201
Mon 7/13
Mon 7/20
1 adult, Economy
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Cheap flight deals from Mississippi to San Diego

Cheapest flights from Mississippi to San Diego
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.

This Frontier deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:48 pm
MEM
-
SAN
1 stop6h 03m
Frontier
Wed 8/196:25 am
SAN
-
MEM
1 stop10h 49m
Frontier
Deal found 6/9$242
This CheapOair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:48 pm
MEM
-
SAN
1 stop15h 17m
Frontier
Wed 7/156:25 am
SAN
-
MEM
1 stop10h 38m
Frontier
Deal found 6/11$250
This Expedia deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:48 pm
MEM
-
SAN
1 stop15h 17m
Frontier
Wed 8/56:25 am
SAN
-
MEM
1 stop10h 38m
Frontier
Deal found 6/9$269
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:44 am
MEM
-
SAN
1 stop6h 41m
American Airlines
Mon 10/51:22 pm
SAN
-
MEM
1 stop8h 30m
American Airlines
Deal found 6/11$285
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am
JAN
-
SAN
1 stop5h 29m
American Airlines
Sat 8/2912:06 pm
SAN
-
JAN
1 stop8h 13m
American Airlines
Deal found 6/11$287
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:20 am
MEM
-
SAN
2 stops7h 15m
Southwest
Tue 8/1110:40 pm
SAN
-
MEM
1 stop8h 20m
Southwest
Deal found 6/8$290
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:20 am
JAN
-
SAN
2 stops10h 06m
United Airlines
Sat 8/2912:01 pm
SAN
-
JAN
1 stop6h 04m
United Airlines
Deal found 6/11$292
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:49 pm
MEM
-
SAN
1 stop8h 06m
Delta
Tue 10/62:00 pm
SAN
-
MEM
1 stop7h 06m
Delta
Deal found 6/10$294
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:05 am
JAN
-
SAN
2 stops9h 20m
Southwest
Sat 8/298:50 am
SAN
-
JAN
2 stops8h 15m
Southwest
Deal found 6/11$297
This Expedia deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:48 pm
MEM
-
SAN
1 stop6h 03m
Frontier
Fri 7/246:25 am
SAN
-
MEM
1 stop10h 38m
Frontier
Deal found 6/8$308
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:53 pm
MEM
-
SAN
1 stop9h 12m
Delta
Mon 9/289:45 pm
SAN
-
MEM
1 stop8h 02m
Delta
Deal found 6/11$311
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:35 pm
MEM
-
SAN
1 stop5h 40m
Southwest
Tue 10/68:55 am
SAN
-
MEM
2 stops9h 10m
Southwest
Deal found 6/10$312

Find flight deals from Mississippi to San Diego

Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated June 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$242
(Frontier)

One-way from

$99
(Kiwi.com)

Popular in

May

Cheapest in

August

Average price

$817
Provider with most accurate pricing for Jackson-Evers Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-San Diego flights.
Search Deals
From Mississippi to San Diego
Search Deals
One-way flight from Mississippi to San Diego
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($215 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Sat 8/15

4:10 pm-9:25 pm

1 stop7h 15m

San Diego

Sat 8/22

7:41 pm-8:43 am

2 stops11h 02m

$326

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Fri 9/4

10:26 am-5:04 pm

1 stop8h 38m

San Diego

Sun 9/6

6:15 am-3:08 pm

1 stop6h 53m

$337

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Thu 9/10

6:59 pm-10:55 pm

1 stop5h 56m

San Diego

Mon 9/14

2:00 pm-11:19 pm

1 stop7h 19m

$337

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

Sat 10/3

12:00 pm-5:06 pm

1 stop7h 06m

San Diego

Mon 10/19

10:40 pm-8:30 am

1 stop7h 50m

$340

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Fri 9/11

11:44 am-8:02 pm

2 stops10h 18m

San Diego

Sat 9/12

10:11 am-6:49 pm

1 stop6h 38m

$342

AlexandriaSan Diego

AEX - SAN

AEXSAN

Alexandria

Mon 6/29

4:00 pm-7:50 pm

1 stop5h 50m

San Diego

Mon 7/6

6:15 am-3:25 pm

1 stop7h 10m

$363

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

Thu 12/10

6:00 am-1:08 pm

1 stop9h 08m

San Diego

Mon 12/14

10:40 pm-8:30 am

1 stop7h 50m

$384

AlexandriaSan Diego

AEX - SAN

AEXSAN

Alexandria

Fri 6/26

4:00 pm-9:24 pm

1 stop7h 24m

San Diego

Sun 7/12

6:15 am-3:25 pm

1 stop7h 10m

$388

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

Thu 12/3

12:10 pm-6:42 pm

1 stop8h 32m

San Diego

Mon 12/7

10:40 pm-8:30 am

1 stop7h 50m

$389

JacksonSan Diego

JAN - SAN

JANSAN

Jackson-Evers Intl

Tue 9/22

2:05 pm-5:46 pm

1 stop5h 41m

San Diego

Wed 9/23

10:11 am-8:20 pm

1 stop8h 09m

$399

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Mississippi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Diego

What is the cheapest month to book a flight from Mississippi to San Diego?

Currently, February is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $145). Flying from Mississippi to San Diego in June is currently the most expensive (average of $457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Mississippi to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mississippi?

    For a flight from Mississippi to San Diego, you will be flying into San Diego. San Diego (SAN) is just 2.6 mi from the center of the city.

  • How long is the flight from Mississippi to San Diego?

    United Airlines, Delta, and Southwest can get you from Mississippi to San Diego in just under 5h 35m. Your travel time can differ by up to 3h 03m. Mississippi and San Diego are separated by a distance of 1563 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to San Diego one-way?

    One-way options have recently been found by users for as low as $138 on American Airlines. Other airlines that offer cheap prices include Delta from $168 and United Airlines from $188 one-way.

  • What are the most popular routes from Mississippi to San Diego?

    The most popular flight routes from Mississippi to San Diego are Memphis - San Diego, Gulfport Biloxi Regional - San Diego and Jackson-Evers Intl - San Diego.

  • Can I find deals for flights from Mississippi to San Diego that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Diego.

  • Can I find deals for business class flights from Mississippi to San Diego?

    Yes. Cheapflights offers flight deals from Mississippi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Diego?

    Currently, February is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $145). Flying from Mississippi to San Diego in June is currently the most expensive (average of $457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
National City
Chula Vista
Poway
Coronado
La Mesa
Santee
Julian
Lemon Grove

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Alternative routes for Mississippi to San Diego

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Top 4 airlines flying from Mississippi to San Diego

Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$472FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$529FlexibilityNo cancel feeOn-time69%
DeltaCheapest$276Average$327FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$336Average$568FlexibilityNo cancel feeOn-time63%

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