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San Diego

$128+ Cheap flights from Mississippi to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
Jul 17 — Jul 241
Fri 7/17
Fri 7/24
1 adult, Economy
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Cheap flight deals from Mississippi to San Diego

Cheapest flights from Mississippi to San Diego
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.

This Priceline deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:59 pm
MEM
-
SAN
1 stop5h 54m
Frontier
Wed 9/29:37 am
SAN
-
MEM
1 stop7h 37m
Frontier
Deal found 6/13$258
This Expedia deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:48 pm
MEM
-
SAN
1 stop15h 17m
Frontier
Wed 7/156:25 am
SAN
-
MEM
1 stop10h 38m
Frontier
Deal found 6/16$272
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:31 pm
MEM
-
SAN
1 stop25h 27m
Multiple Airlines
Sat 8/229:37 am
SAN
-
MEM
2 stops22h 33m
Multiple Airlines
Deal found 6/16$273
This Frontier deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:48 pm
MEM
-
SAN
1 stop6h 03m
Frontier
Wed 8/196:25 am
SAN
-
MEM
1 stop10h 49m
Frontier
Deal found 6/12$278
This Expedia deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:48 pm
MEM
-
SAN
1 stop15h 17m
Frontier
Wed 7/156:25 am
SAN
-
MEM
1 stop10h 38m
Frontier
Deal found 6/12$288
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:28 pm
MEM
-
SAN
1 stop18h 40m
Multiple Airlines
Thu 7/308:51 pm
SAN
-
MEM
1 stop21h 47m
Multiple Airlines
Deal found 6/16$296
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/209:28 pm
MEM
-
SAN
1 stop18h 40m
Multiple Airlines
Wed 7/2210:00 am
SAN
-
MEM
1 stop7h 03m
Multiple Airlines
Deal found 6/14$297
This Expedia deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:48 pm
MEM
-
SAN
1 stop15h 17m
Frontier
Mon 7/276:25 am
SAN
-
MEM
1 stop10h 38m
Frontier
Deal found 6/12$308
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:21 pm
MEM
-
SAN
1 stop8h 36m
Delta
Tue 7/2810:30 pm
SAN
-
MEM
1 stop8h 57m
Delta
Deal found 6/15$311
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:25 pm
MEM
-
SAN
2 stops7h 55m
Southwest
Tue 7/218:05 am
SAN
-
MEM
1 stop5h 30m
Southwest
Deal found 6/16$316
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:09 pm
AEX
-
SAN
1 stop7h 48m
Delta
Thu 8/612:32 pm
SAN
-
AEX
1 stop7h 09m
Delta
Deal found 6/15$318
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:16 pm
BTR
-
SAN
1 stop7h 43m
American Airlines
Tue 8/41:55 pm
SAN
-
BTR
1 stop7h 02m
American Airlines
Deal found 6/14$321

Find flight deals from Mississippi to San Diego

Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated June 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$258
(Priceline)

One-way from

$128
(Kiwi.com)

Popular in

May

Cheapest in

December

Average price

$817
Provider with most accurate pricing for Jackson-Evers Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-San Diego flights.
Search Deals
From Mississippi to San Diego
Search Deals
One-way flight from Mississippi to San Diego
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($211 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Tue 7/14

4:21 pm-10:57 pm

1 stop8h 36m

San Diego

Tue 7/28

10:30 pm-9:27 am

1 stop8h 57m

$311

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Wed 9/9

2:09 pm-8:37 pm

1 stop8h 28m

San Diego

Wed 9/16

6:15 am-4:56 pm

1 stop8h 41m

$311

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Sat 11/7

5:55 pm-11:03 pm

1 stop7h 08m

San Diego

Tue 11/10

12:50 pm-11:06 pm

1 stop8h 16m

$324

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Wed 9/9

12:25 pm-6:20 pm

1 stop7h 55m

San Diego

Sat 9/12

11:10 am-8:55 pm

2 stops7h 45m

$329

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

Tue 7/14

5:08 pm-9:24 pm

1 stop6h 16m

San Diego

Tue 7/21

6:15 am-4:19 pm

1 stop8h 04m

$331

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Sat 8/8

2:05 pm-5:41 pm

1 stop5h 36m

San Diego

Mon 8/10

7:41 pm-8:43 am

2 stops11h 02m

$334

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Sat 10/10

11:32 am-5:46 pm

1 stop8h 14m

San Diego

Sat 10/17

3:00 pm-10:40 pm

1 stop5h 40m

$337

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Fri 9/4

10:26 am-5:04 pm

1 stop8h 38m

San Diego

Sun 9/6

6:15 am-3:08 pm

1 stop6h 53m

$337

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Thu 9/17

1:44 pm-9:05 pm

1 stop9h 21m

San Diego

Sun 9/20

9:45 pm-9:21 am

1 stop9h 36m

$337

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Thu 9/10

6:59 pm-10:55 pm

1 stop5h 56m

San Diego

Mon 9/14

2:00 pm-11:19 pm

1 stop7h 19m

$337

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/14

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Mississippi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Diego

What is the cheapest month to book a flight from Mississippi to San Diego?

Currently, February is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $145). Flying from Mississippi to San Diego in June is currently the most expensive (average of $457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Mississippi to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mississippi?

    For a flight from Mississippi to San Diego, you will be flying into San Diego. San Diego (SAN) is just 2.6 mi from the center of the city.

  • How long is the flight from Mississippi to San Diego?

    Delta, Southwest, and United Airlines can get you from Mississippi to San Diego in just under 6h 16m. Your travel time can differ by up to 2h 20m. Mississippi and San Diego are separated by a distance of 1701 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to San Diego one-way?

    One-way options have recently been found by users for as low as $138 on American Airlines. Other airlines that offer cheap prices include Delta from $168 and United Airlines from $188 one-way.

  • What are the most popular routes from Mississippi to San Diego?

    The most popular flight routes from Mississippi to San Diego are Memphis - San Diego, Gulfport Biloxi Regional - San Diego and Jackson-Evers Intl - San Diego.

  • Can I find deals for flights from Mississippi to San Diego that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Diego.

  • Can I find deals for business class flights from Mississippi to San Diego?

    Yes. Cheapflights offers flight deals from Mississippi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Diego?

    Currently, February is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $145). Flying from Mississippi to San Diego in June is currently the most expensive (average of $457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
National City
Chula Vista
Poway
Coronado
La Mesa
Santee
Julian
Lemon Grove

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Top 4 airlines flying from Mississippi to San Diego

Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$472FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$529FlexibilityNo cancel feeOn-time69%
DeltaCheapest$276Average$327FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$336Average$568FlexibilityNo cancel feeOn-time63%

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