$460+ Cheap flights from Greenville (GSP) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — PTY
Jul 6 — Jul 131
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to Panama with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Panama
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Cheapest flights from Greenville to PanamaExplore the most affordable flight options available from Greenville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 6, 2026.
Explore the most affordable flight options available from Greenville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 6, 2026.
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:55 am
GSP
- PTY
1 stop7h 00m
Delta
Tue 8/252:20 pm
PTY
- GSP
1 stop7h 39m
Delta
Deal found 6/1![Delta logo]()
$527
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
GSP
- PTY
1 stop8h 14m
United Airlines
Wed 8/193:30 pm
PTY
- GSP
2 stops17h 05m
United Airlines
Deal found 6/1![United Airlines logo]()
$531
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:46 am
GSP
- PTY
1 stop8h 09m
Delta
Wed 8/192:20 pm
PTY
- GSP
1 stop7h 39m
Delta
Deal found 6/2![Delta logo]()
$547
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:00 am
GSP
- PTY
1 stop6h 24m
American Airlines
Thu 10/153:35 pm
PTY
- GSP
1 stop6h 39m
American Airlines
Deal found 6/1![American Airlines logo]()
$564
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:30 am
GSP
- PTY
1 stop14h 01m
United Airlines
Mon 7/2710:55 pm
PTY
- GSP
1 stop10h 42m
United Airlines
Deal found 6/5![United Airlines logo]()
$565
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:49 pm
GSP
- PTY
1 stop24h 42m
United Airlines
Mon 7/1310:55 pm
PTY
- GSP
2 stops21h 31m
United Airlines
Deal found 6/2![United Airlines logo]()
$566
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:32 pm
GSP
- PTY
2 stops18h 42m
American Airlines
Mon 7/131:14 pm
PTY
- GSP
2 stops20h 36m
American Airlines
Deal found 6/1![American Airlines logo]()
$575
Best flights from Greenville to PanamaDiscover carefully curated flight deals from Greenville to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 6, 2026.
Discover carefully curated flight deals from Greenville to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 6, 2026.
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:00 am
GSP
- PTY
1 stop8h 14m
United Airlines
Wed 8/510:55 pm
PTY
- GSP
1 stop10h 42m
United Airlines
Deal found 6/1![United Airlines logo]()
$527
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:46 am
GSP
- PTY
1 stop8h 09m
Delta
Wed 8/192:20 pm
PTY
- GSP
1 stop7h 39m
Delta
Deal found 6/5![Delta logo]()
$557
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
GSP
- PTY
1 stop8h 14m
United Airlines
Wed 8/193:30 pm
PTY
- GSP
2 stops17h 05m
United Airlines
Deal found 6/1![United Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:33 am
GSP
- PTY
2 stops18h 31m
United Airlines
Tue 8/2510:00 am
PTY
- GSP
2 stops22h 35m
United Airlines
Deal found 6/1![United Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:18 am
GSP
- PTY
1 stop9h 13m
United Airlines
Mon 10/129:45 am
PTY
- GSP
1 stop12h 44m
United Airlines
Deal found 6/3![United Airlines logo]()
$547
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:00 pm
GSP
- PTY
1 stop8h 31m
United Airlines
Tue 9/223:30 pm
PTY
- GSP
2 stops17h 05m
United Airlines
Deal found 6/5![United Airlines logo]()
$561
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:49 pm
GSP
- PTY
1 stop24h 42m
United Airlines
Mon 7/1310:55 pm
PTY
- GSP
1 stop10h 42m
United Airlines
Deal found 6/2![United Airlines logo]()
$561
Last-minute flights from Greenville to PanamaDiscover last-minute flight deals from Greenville to Panama. Data last updated June 6, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Panama. Data last updated June 6, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:20 am
GSP
- PTY
1 stop14h 11m
United Airlines
Wed 6/2410:00 am
PTY
- GSP
1 stop10h 59m
United Airlines
Deal found 6/2![United Airlines logo]()
$605
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:15 pm
GSP
- PTY
1 stop16h 58m
American Airlines
Fri 6/261:15 pm
PTY
- GSP
1 stop21h 27m
American Airlines
Deal found 6/1![American Airlines logo]()
$616
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:40 pm
GSP
- PTY
2 stops23h 57m
United Airlines
Tue 7/79:45 am
PTY
- GSP
2 stops23h 10m
United Airlines
Deal found 6/2![United Airlines logo]()
$614
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:49 pm
GSP
- PTY
1 stop24h 42m
United Airlines
Mon 7/1310:55 pm
PTY
- GSP
1 stop10h 42m
United Airlines
Deal found 6/2![United Airlines logo]()
$561
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:32 pm
GSP
- PTY
2 stops18h 42m
American Airlines
Mon 7/131:14 pm
PTY
- GSP
2 stops20h 36m
American Airlines
Deal found 6/1![American Airlines logo]()
$575
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:30 am
GSP
- PTY
1 stop14h 01m
United Airlines
Mon 7/2710:55 pm
PTY
- GSP
1 stop10h 42m
United Airlines
Deal found 6/5![United Airlines logo]()
$565
One-way flights from Greenville to PanamaSearch for one-way flight options from Greenville to Panama. Find affordable one-way fares based on user searches. Data last updated June 6, 2026.
Search for one-way flight options from Greenville to Panama. Find affordable one-way fares based on user searches. Data last updated June 6, 2026.
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:20 am
GSP
- PTY
1 stop14h 11m
United Airlines
Deal found 6/5![United Airlines logo]()
$460
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:49 pm
GSP
- PTY
1 stop24h 42m
United Airlines
Deal found 6/5![United Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:49 pm
GSP
- PTY
1 stop9h 15m
United Airlines
Deal found 6/5![United Airlines logo]()
$480
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 pm
GSP
- PTY
2 stops19h 13m
American Airlines
Deal found 6/5![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/232:35 pm
GSP
- PTY
2 stops22h 38m
American Airlines
Deal found 6/5![American Airlines logo]()
$581
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:45 am
GSP
- PTY
2 stops23h 20m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$1,068
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:00 pm
GSP
- PTY
2 stops19h 13m
American Airlines
Deal found 6/5![American Airlines logo]()
$1,165
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2211:07 am
GSP
- PTY
3 stops51h 53m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$1,257
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/231:09 pm
GSP
- PTY
3 stops49h 56m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$1,707
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:44 am
GSP
- PTY
3 stops36h 18m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$2,104
Find flight deals from Greenville to Panama
Keep the following information in mind while searching for Greenville to Panama flight deals. Data was last updated June 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $527 (United Airlines) |
Popular in | December |
Cheapest in | August |
Average price | $648 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
Use the filters below to find and compare flights from Greenville to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Tue 8/4
7:00 am-2:14 pm
1 stop8h 14m
Panama City Tocumen Intl
Wed 8/5
10:55 pm-10:37 am
1 stop10h 42m
$527
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Tue 8/11
7:00 am-2:14 pm
1 stop8h 14m
Panama City Tocumen Intl
Wed 8/19
3:30 pm-9:35 am
2 stops17h 05m
$531
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Tue 8/11
10:33 am-4:04 am
2 stops18h 31m
Panama City Tocumen Intl
Tue 8/25
10:00 am-9:35 am
2 stops22h 35m
$531
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Thu 10/8
11:18 am-7:31 pm
1 stop9h 13m
Panama City Tocumen Intl
Mon 10/12
9:45 am-11:29 pm
1 stop12h 44m
$547
Quickest round-trip
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Tue 8/11
5:46 am-12:55 pm
1 stop8h 09m
Panama City Tocumen Intl
Wed 8/19
2:20 pm-10:59 pm
1 stop7h 39m
$557
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Wed 9/16
12:00 pm-7:31 pm
1 stop8h 31m
Panama City Tocumen Intl
Tue 9/22
3:30 pm-9:35 am
2 stops17h 05m
$561
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Mon 7/6
7:49 pm-7:31 pm
1 stop24h 42m
Panama City Tocumen Intl
Mon 7/13
10:55 pm-10:37 am
1 stop10h 42m
$561
Cheapest one-way
Quickest one-way
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Tue 6/23
6:30 am-7:31 pm
1 stop14h 01m
$460
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Thu 6/25
6:00 am-7:31 pm
1 stop14h 31m
$460
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Wed 6/24
7:49 pm-7:31 pm
1 stop24h 42m
$477
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from Greenville to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Greenville with our price prediction graph.
GSP-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Panama
GSP-PA0
GSP-PTY
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated June 6, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Greenville to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Entertainment
7.1
Crew
8.1
Comfort
7.3
Overall
7.4
Food
6.6
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Entertainment
7.1
Crew
8.1
Comfort
7.3
Overall
7.4
Food
6.6
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Entertainment
7.1
Crew
8.1
Comfort
7.3
Overall
7.4
Food
6.6
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from Greenville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Alternative routes for Greenville to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to Panama by cabin class
Find flights from Greenville to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and Panama flights
Browse other Greenville and Panama flight options. Last updated on June 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Greenville to Panama
Discover the top 2 airlines that operate flights from Greenville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$391 | Average$485 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$421 | Average$664 | FlexibilityNo cancel fee | On-time71% |