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$306+ Cheap flights from La Crosse to Charleston (LSE - CHS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — CHS
Jul 6 — Jul 131
Mon 7/6
Mon 7/13
1 adult, Economy
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Cheap flight deals from La Crosse to Charleston

Cheapest flights from La Crosse to Charleston
Explore the most affordable flight options available from La Crosse to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 6, 2026.

This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:19 pm
LSE
-
CHS
1 stop4h 56m
American Airlines
Sat 10/178:01 pm
CHS
-
LSE
1 stop4h 18m
American Airlines
Deal found 6/3$306
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:52 am
LSE
-
CHS
2 stops10h 55m
American Airlines
Sat 6/207:24 am
CHS
-
LSE
1 stop4h 43m
American Airlines
Deal found 6/1$348
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:01 pm
LSE
-
CHS
2 stops8h 53m
American Airlines
Tue 7/218:21 pm
CHS
-
LSE
1 stop4h 38m
American Airlines
Deal found 6/3$351
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:01 pm
LSE
-
CHS
1 stop6h 30m
American Airlines
Sat 8/17:30 am
CHS
-
LSE
1 stop5h 01m
American Airlines
Deal found 6/3$398
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 am
LSE
-
CHS
1 stop4h 54m
American Airlines
Wed 7/88:21 pm
CHS
-
LSE
1 stop4h 38m
American Airlines
Deal found 6/5$400

Find flight deals from La Crosse to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$306
(American Airlines)
Provider with most accurate pricing for La Crosse-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for La Crosse-Charleston flights.
Search Deals
From La Crosse to Charleston
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
Use the filters below to find and compare flights from La Crosse to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

Wed 10/14

6:19 pm-12:15 am

1 stop4h 56m

Charleston

Sat 10/17

8:01 pm-11:19 pm

1 stop4h 18m

$306

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

Tue 6/16

11:52 am-11:47 pm

2 stops10h 55m

Charleston

Sat 6/20

7:24 am-11:07 am

1 stop4h 43m

$348

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

Fri 7/17

12:01 pm-9:54 pm

2 stops8h 53m

Charleston

Tue 7/21

8:21 pm-11:59 pm

1 stop4h 38m

$351

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

Wed 7/29

12:01 pm-7:31 pm

1 stop6h 30m

Charleston

Sat 8/1

7:30 am-11:31 am

1 stop5h 01m

$398

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

Thu 7/2

6:00 am-11:54 am

1 stop4h 54m

Charleston

Wed 7/8

8:21 pm-11:59 pm

1 stop4h 38m

$400

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/3

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on La Crosse-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on La Crosse-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from La Crosse to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated June 6, 2026.
Read through reviews of airlines operating flights from La Crosse to Charleston, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,649 reviews

Overall

7.1

Food

6.4

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,649 reviews
American Airlines
7.1
Good
11,649 reviews

Overall

7.1

Food

6.4

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from La Crosse to Charleston?

    American Airlines can get you from La Crosse to Charleston in just under 4h 56m. Your travel time can differ by up to . The distance from La Crosse to Charleston is about 970 mi.

  • What is the cheapest airline to fly from La Crosse to Charleston round-trip?

    According to our current data, American Airlines ($299), offers the cheapest pricing from La Crosse to Charleston.

  • Can I find deals for flights from La Crosse to Charleston that include hotel bookings?

    Yes. In addition to deals on La Crosse to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Charleston.

  • Can I find deals for business class flights from La Crosse to Charleston?

    Yes. Cheapflights offers flight deals from La Crosse to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach

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Top airline flying from La Crosse to Charleston

Discover the top airline that operate flights from La Crosse to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$299Average$604FlexibilityNo cancel feeOn-time71%

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